102 research outputs found
A Sequence-to-Sequence&Set Model for Text-to-Table Generation
Recently, the text-to-table generation task has attracted increasing
attention due to its wide applications. In this aspect, the dominant model
formalizes this task as a sequence-to-sequence generation task and serializes
each table into a token sequence during training by concatenating all rows in a
top-down order. However, it suffers from two serious defects: 1) the predefined
order introduces a wrong bias during training, which highly penalizes shifts in
the order between rows; 2) the error propagation problem becomes serious when
the model outputs a long token sequence. In this paper, we first conduct a
preliminary study to demonstrate the generation of most rows is
order-insensitive. Furthermore, we propose a novel sequence-to-sequence&set
text-to-table generation model. Specifically, in addition to a text encoder
encoding the input text, our model is equipped with a table header generator to
first output a table header, i.e., the first row of the table, in the manner of
sequence generation. Then we use a table body generator with learnable row
embeddings and column embeddings to generate a set of table body rows in
parallel. Particularly, to deal with the issue that there is no correspondence
between each generated table body row and target during training, we propose a
target assignment strategy based on the bipartite matching between the first
cells of generated table body rows and targets. Experiment results show that
our model significantly surpasses the baselines, achieving state-of-the-art
performance on commonly-used datasets
Preparation of Flame Retardant Modified with Titanate for Asphalt Binder
Improving the compatibility between flame retardant and asphalt is a difficult task due to the complex nature of the materials. This study explores a low dosage compound flame retardant and seeks to improve the compatibility between flame retardants and asphalt. An orthogonal experiment was designed taking magnesium hydroxide, ammonium polyphosphate, and melamine as factors. The oil absorption and activation index were tested to determine the effect of titanate on the flame retardant additive. The pavement performance test was conducted to evaluate the effect of the flame retardant additive. Oxygen index test was conducted to confirm the effect of flame retardant on flame ability of asphalt binder. The results of this study showed that the new composite flame retardant is more effective in improving the compatibility between flame retardant and asphalt and reducing the limiting oxygen index of asphalt binder tested in this study
Influence of coal characteristics on laser-induced plasmas
peer reviewedEight kinds of typical coal samples were chosen for studying the influence of coal
characteristics on laser—induced plasmas.Element analysis and industry analysis were carried out for every sample.Experimental study on the interaction between laser and different coal samples was completed,and factors affecting laser plasma were analyzed,such as coal moisture and coal dust.The experiment result indicates that the coal samples with different coalification degrees have different plasma time—resolved spectral characteristics,all of them tend to rise at the beginning of plasma formation (< 1us),then with the decay of plasmas emission.they tend to decrease in about 1us,while secondary ionization occurs in highly coalificated coals after 2 us.The plasma temperature differs from one kind to another,the higher the coalification degree is,the higher the plasma temperature will be
Inhibitory Effects of Dopamine Receptor D1 Agonist on Mammary Tumor and Bone Metastasis
Dopaminergic signaling plays a critical role in the nervous system, but little is known about its potential role in breast cancer and bone metabolism. A screening of ~1,000 biologically active compounds revealed that a selective agonist of dopamine receptor D1 (DRD1), A77636, inhibited proliferation of 4T1.2 mammary tumor cells as well as MDA-MB-231 breast cancer cells. Herein, we examined the effect of A77636 on bone quality using a mouse model of bone metastasis from mammary tumor. A77636 inhibited migration of cancer cells in a DRD1-dependent fashion and suppressed development of bone-resorbing osteoclasts by downregulating NFATc1 through the elevation of phosphorylation of eIF2α. In the mouse model of bone metastasis, A77636 reduced osteolytic lesions and prevented mechanical weakening of the femur and tibia. Collectively, we expect that dopaminergic signaling might provide a novel therapeutic target for breast cancer and bone metastasis
Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes
Aim. This study aimed to evaluate the association between cardiovascular autonomic neuropathy (CAN) and left ventricular diastolic dysfunction (LVDD) in type 2 diabetes patients. Methods. 315 type 2 diabetes patients from inpatients of Drum Tower Hospital were included and classified into no CAN (NCAN), possible CAN (PCAN), and definite CAN (DCAN) based on cardiovascular autonomic reflex tests. The left ventricular diastolic function was assessed by tissue Doppler imaging echocardiography. Results. The distribution of NCAN, PCAN, and DCAN was 11.4%, 51.1%, and 37.5%, respectively. The proportion of LVDD increased among the groups of NCAN, PCAN, and DCAN (39.4%, 45.3%, and 68.0%, = 0.001). Patients with DCAN had higher filling pressure ( / ratio) (10.9 ± 2.7 versus 9.4 ± 2.8, = 0.013) and impaired diastolic performance ( ) (6.8 ± 1.7 versus 8.6±2.4, = 0.004) compared with NCAN. CAN was found to be an independent risk factor for LVDD from the multivariate regression analysis (OR = 1.628, = 0.009, 95% CI 1.131-2.344). Conclusions. Our results indicated that CAN was an independent risk marker for the presence of LVDD in patients with diabetes. Early diagnosis and treatment of CAN are advocated for preventing LVDD in type 2 diabetes
Analysis of the Lovemarks Concept in Sport Industry
Import 05/08/2014Bakalářská práce se zabývá analýzou konceptu lovemarks ve sportovním průmyslu. Práce je rozdělena na dvě základní části, na část teoretickou a praktickou. V teoretické části práce jsou vymezeny pojmy nutné k pochopení dané problematiky. V praktické části byla pomocí metody dotazníkového šetření provedena analýza konceptu lovemarks. V závěrečné části jsou shrnuty výsledky šetření a doporučení.Bachelor thesis deals with the analysis of the lovemarks concept in sport industry. The thesis is structured into two fundamental sections, theoretical and practical. In the theoretical section are defined terms, which are necessary to understand given issue. In the practical section was used the questionnaire method to analyse lovemarks concept. In the final part are summarized results of research and recommendations.115 - Katedra managementuvýborn
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Dent Disease in Chinese Children and Findings from Heterozygous Mothers: Phenotypic Heterogeneity, Fetal Growth, and 10 Novel Mutations.
Par Antoine Blanchard et Mélodie Faury pour le collectif Révoluscience Billet publié simultanément sur Sciences et Démocratie et Knowtex Blog Les "lieux" des réactions Plusieurs dispositifs avaient été mis en place pour recueillir les réactions des lecteurs, d'abord sur le blog du manifeste où les commentaires étaient possibles sous chaque proposition, puis sur un site de travail collaboratif permettant d’en annoter le texte, paragraphe par paragraphe. On alliait ainsi critique d'un côté et..
Application of Angiotensin Receptor–Neprilysin Inhibitor in Chronic Kidney Disease Patients: Chinese Expert Consensus
Chronic kidney disease (CKD) is a global public health problem, and cardiovascular disease is the most common cause of death in patients with CKD. The incidence and prevalence of cardiovascular events during the early stages of CKD increases significantly with a decline in renal function. More than 50% of dialysis patients die from cardiovascular disease, including coronary heart disease, heart failure, arrhythmia, and sudden cardiac death. Therefore, developing effective methods to control risk factors and improve prognosis is the primary focus during the diagnosis and treatment of CKD. For example, the SPRINT study demonstrated that CKD drugs are effective in reducing cardiovascular and cerebrovascular events by controlling blood pressure. Uncontrolled blood pressure not only increases the risk of these events but also accelerates the progression of CKD. A co-crystal complex of sacubitril, which is a neprilysin inhibitor, and valsartan, which is an angiotensin receptor blockade, has the potential to be widely used against CKD. Sacubitril inhibits neprilysin, which further reduces the degradation of natriuretic peptides and enhances the beneficial effects of the natriuretic peptide system. In contrast, valsartan alone can block the angiotensin II-1 (AT1) receptor and therefore inhibit the renin–angiotensin–aldosterone system. These two components can act synergistically to relax blood vessels, prevent and reverse cardiovascular remodeling, and promote natriuresis. Recent studies have repeatedly confirmed that the first and so far the only angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan can reduce blood pressure more effectively than renin–angiotensin system inhibitors and improve the prognosis of heart failure in patients with CKD. Here, we propose clinical recommendations based on an expert consensus to guide ARNI-based therapeutics and reduce the occurrence of cardiovascular events in patients with CKD
Dent Disease in Chinese Children and Findings from Heterozygous Mothers: Phenotypic Heterogeneity, Fetal Growth, and 10 Novel Mutations.
OBJECTIVE: To characterize the phenotypes of Dent disease in Chinese children and their heterozygous mothers and to establish genetic diagnoses. STUDY DESIGN: Using a modified protocol, we screened 1288 individuals with proteinuria. A diagnosis of Dent disease was established in 19 boys from 16 families by the presence of loss of function/deleterious mutations in CLCN5 or OCRL1. We also analyzed 16 available patients' mothers and examined their pregnancy records. RESULTS: We detected 14 loss of function/deleterious mutations of CLCN5 in 15 boys and 2 mutations of OCRL1 in 4 boys. Of the patients, 16 of 19 had been wrongly diagnosed with other diseases and 11 of 19 had incorrect or unnecessary treatment. None of the patients, but 6 of 14 mothers, had nephrocalcinosis or nephrolithiasis at diagnosis. Of the patients, 8 of 14 with Dent disease 1 were large for gestational age (>90th percentile); 8 of 15 (53.3%) had rickets. We also present predicted structural changes for 4 mutant proteins. CONCLUSIONS: Pediatric Dent disease often is misdiagnosed; genetic testing achieves a correct diagnosis. Nephrocalcinosis or nephrolithiasis may not be sensitive diagnostic criteria. We identified 10 novel mutations in CLCN5 and OCRL1. The possibility that altered CLCN5 function could affect fetal growth and a possible link between a high rate of rickets and low calcium intake are discussed
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