Bis(2-amino-5-methyl-1,3,4-thia­diazole-κN 3)dichloridocobalt(II)

In the monomeric title complex, [CoCl2(C3H5N3S)2], the CoII atom is tetra­coordinated by two chloride anions and two N atoms from two monodentate 2-amino-5-methyl-1,3,4-thia­diazole ligands, giving a slightly distorted tetra­hedral stereochemistry [bond angle range about Co = 105.16 (12)–112.50 (10)°]. In the complex, the dihedral angle between the 1,3,4-thia­diazole planes in the two ligands is 72.8 (1)°. There are two intra­molecular N—H⋯Cl inter­actions in the complex unit, while in the crystal, inter­molecular N—H⋯N and N—H⋯Cl hydrogen bonds link these units into a two-dimensional layered structure parallel to (011)

High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention

Receiver-operating characteristic curve predicting stent thrombosis. (TIFF 5134 kb

Ising Hamiltonians for Constrained Combinatorial Optimization Problems and the Metropolis-Hastings Warm-Starting Algorithm

Quantum approximate optimization algorithm (QAOA) is a promising variational quantum algorithm for combinatorial optimization problems. However, the implementation of QAOA is limited due to the requirement that the problems be mapped to Ising Hamiltonians and the nonconvex optimization landscapes. Although the Ising Hamiltonians for many NP hard problems have been obtained, a general method to obtain the Ising Hamiltonians for constrained combinatorial optimization problems (CCOPs) has not yet been investigated. In this paper, a general method is introduced to obtain the Ising Hamiltonians for CCOPs and the Metropolis-Hastings warm-starting algorithm for QAOA is presented which can provably converge to the global optimal solutions. The effectiveness of this method is demonstrated by tackling the minimum weight vertex cover (MWVC) problem, the minimum vertex cover (MVC) problem, and the maximal independent set problem as examples. The Ising Hamiltonian for the MWVC problem is obtained first time by using this method. The advantages of the Metropolis-Hastings warm-starting algorithm presented here is numerically analyzed through solving 30 randomly generated MVC cases with 1-depth QAOA

Broad bandwidth waveguide polarizer via grating mediated mode conversion

A polarization beam splitter (PBS) based on a four-layer slab waveguide is proposed, where a sub-wavelength grating is embedded between the waveguide core and the cladding. This grating not only affords Bragg momentum to tune the propagation constant of guiding modes but also converts the forward zero-order waveguide mode to the backward first one for a specific polarization. Thus, the incident light with polarization that satisfies the phase-matching condition is highly reflected in the waveguide, while other light with orthogonal polarization keeps intact and passes through it efficiently. Numerical simulations show that one can make the compact PBS for both polarizations with an extinction ratio higher than 35 dB, a waveband larger than 80 nm, a grating period tolerance of 20 nm, and a waveguide height tolerance of 80 nm. The revealed mode conversion mechanism via the sub-wavelength grating enriches the design of PBSs for integrated silicon waveguide chips

Quantum Fisher information and coherence in one-dimensional XYXY spin models with Dzyaloshinsky-Moriya interactions

We investigate quantum phase transitions in $XY$ spin models using Dzyaloshinsky-Moriya (DM) interactions. We identify the quantum critical points via quantum Fisher information and quantum coherence, finding that higher DM couplings suppress quantum phase transitions. However, quantum coherence (characterized by the $l_1$-norm and relative entropy) decreases as the DM coupling increases. Herein, we present both analytical and numerical results.Comment: 7 pages, 5 figure

Discrimination of Coherent States via Atom-Field Interaction without Rotation Wave Approximation

The quantum state discrimination is an important part of quantum information processing. We investigate the discrimination of coherent states through Jaynes-Cummings (JC) model interaction between the field and the ancilla without rotation wave approximation (RWA). We show that the minimum failure probability can be reduced as RWA is eliminated from JC model and the non-RWA terms accompanied by the quantum effects of fields (e.g. the virtual photon process in the JC model without RWA) can enhance the state discrimination. The JC model without RWA for unambiguous state discrimination is superior to ambiguous state discrimination, particularly when the number of sequential measurements increases. Unambiguous state discrimination implemented via the non-RWA JC model is beneficial to saving resource cost.Comment: 8 pages, 4 figures. Accepted for publication in Communications in Theoretical Physic

miR-142-5p Improves Neural Differentiation and Proliferation of Adipose-Derived Stem Cells

Background/Aims: MiRNAs may regulate neurogenic differentiation of adipose-derived stem cells (ADSCs). In this study, we hypothesized that the miR-142-5p can repress the expression of RhoA/ROCK1 pathway on the neurogenesis of ADSCs. Methods: Deregulated miRNA during neurogenic differentiation of ADSCs were identified. The expression of neuron-specific enolase (NSE) and β III tubulin (Neuron-specific class III beta-tubulin) were detected as the markers of neurogenic differentiation by immunostaining and western blot. The targeting of miR-142-5p on RhoA and ROCK1 was verified by dual luciferase assay, qRT-PCR and western blot. The roles of miR-142-5p and the RhoA/ROCK1 signaling pathway were explored by using functional experiments including cell viability and colony formation assays. Results: MiR-142-5p is significantly upregulated during neurogenic differentiation of ADSCs. Knockdown of endogenous miR-142-5p hampered neurogenic differentiation. MiR-142-5p could directly target RhoA and ROCK1 mRNA and repress their expressions, through which it increased the proportion of differentiated cells with positive NSE and β III tubulin. RhoA/ROCK1 signaling pathway is involved in miR-142-5p effect on the process of neurogenic differentiation of ADSCs. Conclusion: Our results demonstrate that miR-142-5p functions as a growth promotive miRNA and plays an important role in neurogenic differentiation by targeting RhoA/ROCK1 in ADSCs

Highly tunable polarized chromatic plasmonic films based on sub-wavelength grating templates

A kind of polarized chromatic plasmonic film is proposed based on subwavelength grating structure, which enables “blue transmission” for the transverse electric light and “red transmission” for the transverse magnetic light. Metal–insulator–metal plasmonic waveguiding and metallic nanowire scattering are revealed to be responsible for the chromatic shift. Based upon the unique transmission spectrum characteristics of such films, polarized chromatic plasmonic tags (PCPTs) can be flexibly fabricated by patterning dielectric grating templates with designed figures and depositing appropriate thickness of metal. These PCPTs, simultaneously possessing directly visible unpolarized transmission colors and concealed distinct polarization‐dependent color shift, can be widely used as anti‐counterfeiting tags with higher security than the diffractive types of holograms

Bis[3-(pyrazin-2-yl)-5-(pyridin-2-yl-κN)-1,2,4-triazol-1-ido-κN 1]copper(II)

In the mononuclear title complex, [Cu(C11H7N6)2], the CuII atom lies on a crystallographic inversion centre and is coordinated by four N atoms from two bidentate chelate monoanionic 3-(pyrazin-2-yl)-5-(pyridin-2-yl-1,2,4-triazol-1-ido ligands, two from the triazolide rings [Cu—N = 1.969 (2) Å] and two from the pyridine rings [Cu—N = 2.027 (2) Å], giving a slightly distorted square-planar geometry