117 research outputs found

    An Improved Sideband Current Harmonic Model of Interior PMSM Drive by Considering Magnetic Saturation and Cross-Coupling Effects

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    The sideband current harmonics, as parasitic characteristics in permanent-magnet synchronous machine (PMSM) drives with space vector pulsewidth modulation technique, will increase the corresponding electromagnetic loss, torque ripple, vibration, and acoustic noises. Therefore, fast yet accurate evaluation of the resultant sideband current harmonic components is of particular importance during the design stage of the drive system. However, the inevitable magnetic saturation and cross-coupling effects in interior PMSM drives would have a significant impact on the current components, while the existing analytical sideband current harmonic model neglects those effects. This paper introduces a significant improvement on the analytical model by taking into account these effects with corresponding nonlinear factors. Experimental results are carried out to underpin the accuracy improvements of the predictions from the proposed model over the existing analytical one. The proposed model can offer a very detailed and insightful revelation of impacts of the magnetic saturation and cross-coupling effects on the corresponding sideband current harmonics

    Protective behavior of an SO2/CO2 gas mixture for molten AZ91D alloy

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    The protective behavior for a molten AZ91D alloy in an open melting furnace was investigated under a protective gas mixture containing 3% SO2 and 97% CO2, and the protection mechanism was discussed. Experimental results show that the gas mixture provides effective protection for AZ91D melt in the temperature range from 680 ìC to 730 ìC. The microstructure, chemical composition and phase composition of the surface film formed on the molten AZ91D alloy were analyzed using scanning electron microscopy (SEM) with energy dispersive spectrometer (EDS) and X-ray diffraction (XRD). The SEM results demonstrate that the surface films with an average thickness between 0.5 レm and 2 レm are dense and coherent in the protected temperature range. The EDS results reveal that the surface film mainly contains elements S, C, O, Al and Mg. The XRD results show that the surface film consists of MgO, MgS and a small amount of C phase

    The analytical study of stator tooth modulation on electromagnetic radial force in permanent magnet synchronous machines

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    The electromagnetic radial force acting on the stator inner periphery will induce radial vibration and acoustic noise in permanent magnet machines. The radial force components are transmitted through the stator teeth to the yoke to introduce deformations. The influence of the stator tooth structure can be considered as an equivalent mechanical modulation effect on these electromagnetic radial force components. As a result, high-order electromagnetic radial force components can be modulated and potentially result in eminent stator low-mode vibration. In this paper, an analytical model is developed to offer an intuitive knowledge of stator tooth modulation effect on electromagnetic radial force. The validity of the proposed analytical method has been underpinned by both finite element analysis and experimental results. Such an effective yet simple analytical model can be of significant benefit for the stator radial vibration analysis. It can be employed to not only promptly investigate the stator radial vibration characteristics but also perform effective optimization on stator radial vibration reduction in permanent magnet machine

    Remote Attestation on Function Execution

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    Singapore Management Universit

    Model-Driven Remote Attestation: Attesting Remote System from Behavioral Aspect

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    Ministry of Education, Singapore under its Academic Research Funding Tier 1, Singapore Management Universit

    A Novel Integrated Multifunction Micro-Sensor for Three-Dimensional Micro-Force Measurements

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    An integrated multifunction micro-sensor for three-dimensional micro-force precision measurement under different pressure and temperature conditions is introduced in this paper. The integrated sensor consists of three kinds of sensors: a three-dimensional micro-force sensor, an absolute pressure sensor and a temperature sensor. The integrated multifunction micro-sensor is fabricated on silicon wafers by micromachining technology. Different doping doses of boron ion, placement and structure of resistors are tested for the force sensor, pressure sensor and temperature sensor to minimize the cross interference and optimize the properties. A glass optical fiber, with a ladder structure and sharp tip etched by buffer oxide etch solution, is glued on the micro-force sensor chip as the tactile probe. Experimental results show that the minimum force that can be detected by the force sensor is 300 nN; the lateral sensitivity of the force sensor is 0.4582 mV/μN; the probe length is linearly proportional to sensitivity of the micro-force sensor in lateral; the sensitivity of the pressure sensor is 0.11 mv/KPa; the sensitivity of the temperature sensor is 5.836 × 10−3 KΩ/°C. Thus it is a cost-effective method to fabricate integrated multifunction micro-sensors with different measurement ranges that could be used in many fields

    Differential Responses of MET Activations to MET kinase Inhibitor and Neutralizing Antibody

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    Background: Aberrant MET tyrosine kinase signaling is known to cause cancer initiation and progression. While MET inhibitors are in clinical trials against several cancer types, the clinical efficacies are controversial and the molecular mechanisms toward sensitivity remain elusive. Methods: With the goal to investigate the molecular basis of MET amplification (MET amp ) and hepatocyte growth factor (HGF) autocrine-driven tumors in response to MET tyrosine kinase inhibitors (TKI) and neutralizing antibodies, we compared cancer cells harboring MET amp (MKN45 and MHCCH97H) or HGF-autocrine (JHH5 and U87) for their sensitivity and downstream biological responses to a MET-TKI (INC280) and an anti-MET monoclonal antibody (MetMab) in vitro, and for tumor inhibition in vivo. Results: We find that cancer cells driven by MET amp are more sensitive to INC280 than are those driven by HGF-autocrine activation. In MET amp cells, INC280 induced a DNA damage response with activation of repair through the p53BP1/ATM signaling pathway. Although MetMab failed to inhibit MET amp cell proliferation and tumor growth, both INC280 and MetMab reduced HGF-autocrine tumor growth. In addition, we also show that HGF stimulation promoted human HUVEC cell tube formation via the Src pathway, which was inhibited by either INC280 or MetMab. These observations suggest that in HGF-autocrine tumors, the endothelial cells are the secondary targets MET inhibitors. Conclusions: Our results demonstrate that MET amp and HGF-autocrine activation favor different molecular mechanisms. While combining MET TKIs and ATM inhibitors may enhance the efficacy for treating tumors harboring MET amp , a combined inhibition of MET and angiogenesis pathways may improve the therapeutic efficacy against HGF-autocrine tumors

    Genome-wide characterization of SOS1 gene family in potato (Solanum tuberosum) and expression analyses under salt and hormone stress

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    Salt Overly Sensitive 1 (SOS1) is one of the members of the Salt Overly Sensitive (SOS) signaling pathway and plays critical salt tolerance determinant in plants, while the characterization of the SOS1 family in potato (Solanum tuberosum) is lacking. In this study, 37 StSOS1s were identified and found to be unevenly distributed across 10 chromosomes, with most of them located on the plasma membrane. Promoter analysis revealed that the majority of these StSOS1 genes contain abundant cis-elements involved in various abiotic stress responses. Tissue specific expression showed that 21 of the 37 StSOS1s were widely expressed in various tissues or organs of the potato. Molecular interaction network analysis suggests that 25 StSOS1s may interact with other proteins involved in potassium ion transmembrane transport, response to salt stress, and cellular processes. In addition, collinearity analysis showed that 17, 8, 1 and 5 of orthologous StSOS1 genes were paired with those in tomato, pepper, tobacco, and Arabidopsis, respectively. Furthermore, RT-qPCR results revealed that the expression of StSOS1s were significant modulated by various abiotic stresses, in particular salt and abscisic acid stress. Furthermore, subcellular localization in Nicotiana benthamiana suggested that StSOS1-13 was located on the plasma membrane. These results extend the comprehensive overview of the StSOS1 gene family and set the stage for further analysis of the function of genes in SOS and hormone signaling pathways

    Time series analysis of dengue fever and weather in Guangzhou, China

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    <p>Abstract</p> <p>Background</p> <p>Monitoring and predicting dengue incidence facilitates early public health responses to minimize morbidity and mortality. Weather variables are potential predictors of dengue incidence. This study explored the impact of weather variability on the transmission of dengue fever in the subtropical city of Guangzhou, China.</p> <p>Methods</p> <p>Time series Poisson regression analysis was performed using data on monthly weather variables and monthly notified cases of dengue fever in Guangzhou, China for the period of 2001-2006. Estimates of the Poisson model parameters was implemented using the Generalized Estimating Equation (GEE) approach; the quasi-likelihood based information criterion (QICu) was used to select the most parsimonious model.</p> <p>Results</p> <p>Two best fitting models, with the smallest QICu values, are selected to characterize the relationship between monthly dengue incidence and weather variables. Minimum temperature and wind velocity are significant predictors of dengue incidence. Further inclusion of minimum humidity in the model provides a better fit.</p> <p>Conclusion</p> <p>Minimum temperature and minimum humidity, at a lag of one month, are positively associated with dengue incidence in the subtropical city of Guangzhou, China. Wind velocity is inversely associated with dengue incidence of the same month. These findings should be considered in the prediction of future patterns of dengue transmission.</p
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