Compartmentalization of incompatible reagents within Pickering emulsion droplets for one-pot cascade reactions

It is a dream that future synthetic chemistry can mimic living systems to process multistep cascade reactions in a one-pot fashion. One of the key challenges is the mutual destruction of incompatible or opposing reagents, for example, acid and base, oxidants and reductants. A conceptually novel strategy is developed here to address this challenge. This strategy is based on a layered Pickering emulsion system, which is obtained through lamination of Pickering emulsions. In this working Pickering emulsion, the dispersed phase can separately compartmentalize the incompatible reagents to avoid their mutual destruction, while the continuous phase allows other reagent molecules to diffuse freely to access the compartmentalized reagents for chemical reactions. The compartmentalization effects and molecular transport ability of the Pickering emulsion were investigated. The deacetalization–reduction, deacetalization–Knoevenagel, deacetalization–Henry and diazotization–iodization cascade reactions demonstrate well the versatility and flexibility of our strategy in processing the one-pot cascade reactions involving mutually destructive reagents

Explicit formula of radiation fields of free waves with applications on channel of energy

In this work we give a few explicit formulas regarding the radiation fields of linear free waves. We then apply these formulas on the channel of energy theory. We characterize all the radial weakly non-radiative solutions in all dimensions and give a few new exterior energy estimates.Comment: 26 pages, 1 figur

Visual Presentation Modes in Online Product Reviews and Their Effects on Consumer Responses

Online product reviews posted by consumers are becoming a staple part of e-commerce websites. Researchers demonstrate that the volume and strength of online reviews, among others, have a significant impact on consumer responses. These studies have focused on the effect of text-based online reviews, but current information technologies enable the posting of online reviews with higher visual content, such as with images and videos. Using the Elaboration Likelihood Model and Dual Coding theory, we examine the effects of three visual modes for presenting online reviews with three products – backpack, digital camera and video game. Our results indicate that video-based online reviews are perceived as being more credible, helpful, persuasive, and providing a great sense of involvement, compared to text-based and image-based online reviews, but with no significant differences among the latter two. The influence of presentation modes on consumer responses is partially moderated by product type

Sensitivity of Penman-Monteith reference crop evapotranspiration in Tao\u27 er River Basin of northeastern China

A non-dimensional relative sensitivity coefficient was employed to predict the responses of reference crop evapotranspiration (ET0) to perturbation of four climate variables in Tao\u27er River Basin of the northeastern China. Mean monthly ET0 and yearly ET0 from 1961 to 2005 were estimated with the FAO-56 Penman-Monteith Equation. A 45-year historical dataset of average monthly maximum/minimum air temperature, mean air temperature, wind speed, sunshine hours and relative humidity from 15 meteorological stations was used in the analysis. Results show that: 1) Sensitivity coefficients of wind speed, air temperature and sunshine hours were positive except for those of air temperature of Arxan Meteorological Station, while those of relative humidity were all negative. Relative humidity was the most sensitive variable in general for the Tao\u27er River Basin, followed by sunshine hours, wind speed and air temperature. 2) Similar to climate variable, monthly sensitivity coefficients exhibit large annual fluctuations. 3) Sensitivity coefficients for four climate variables all showed significant trends in seasonal/yearly series. Also, sensitivity coefficients of air temperature, sunshine hours and wind speed all showed significant trends in spring. 4) Among all sensitivity coefficients, the average yearly sensitivity coefficient of relative humidity was highest throughout the basin and showed largest spatial variability. Longitudinal distribution of sensitivity coefficients for air temperature, relative humidity and sunshine hours was also found, which was similar to the distribution of the three climate variables

MPT: Mesh Pre-Training with Transformers for Human Pose and Mesh Reconstruction

We present Mesh Pre-Training (MPT), a new pre-training framework that leverages 3D mesh data such as MoCap data for human pose and mesh reconstruction from a single image. Existing work in 3D pose and mesh reconstruction typically requires image-mesh pairs as the training data, but the acquisition of 2D-to-3D annotations is difficult. In this paper, we explore how to leverage 3D mesh data such as MoCap data, that does not have RGB images, for pre-training. The key idea is that even though 3D mesh data cannot be used for end-to-end training due to a lack of the corresponding RGB images, it can be used to pre-train the mesh regression transformer subnetwork. We observe that such pre-training not only improves the accuracy of mesh reconstruction from a single image, but also enables zero-shot capability. We conduct mesh pre-training using 2 million meshes. Experimental results show that MPT advances the state-of-the-art results on Human3.6M and 3DPW datasets. We also show that MPT enables transformer models to have zero-shot capability of human mesh reconstruction from real images. In addition, we demonstrate the generalizability of MPT to 3D hand reconstruction, achieving state-of-the-art results on FreiHAND dataset

Beneficial effect of fluid warming in elderly patients with bladder cancer undergoing Da Vinci roboticassisted laparoscopic radical cystectomy

OBJECTIVES: The enhanced recovery after surgery (ERAS) protocol recommends prevention of intraoperative hypothermia. However, the beneficial effect of maintaining normothermia after radical cystectomy has not been evaluated. This study aimed to investigate the efficacy of fluid warming nursing in elderly patients undergoing Da Vinci robotic-assisted laparoscopic radical cystectomy. METHODS: A total of 108 patients with bladder cancer scheduled to undergo DaVinci robotic-assisted laparoscopic radical cystectomy were recruited and randomly divided into the control group (n=55), which received a warming blanket (43o C) during the intraoperative period and the warming group (n=53), in which all intraoperative fluids were administered via a fluid warmer (41o C). The surgical data, body temperature, coagulation function indexes, and postoperative complications were compared between the two groups. RESULTS: Compared to the control group, the warming group had significantly less intraoperative transfusion (p=0.028) and shorter hospitalization days (po0.05). During the entire intraoperative period (from 1 to 6h), body temperature was significantly higher in the warming group than in the control group. There were significant differences in preoperative fibrinogen level, white blood cell count, total bilirubin level, intraoperative lactose level, postoperative thrombin time (TT), and platelet count between the control and warming groups. Multivariate linear regression analysis demonstrated that TT was the only significant factor, suggesting that the warming group had a lower TT than the control group. CONCLUSION: Fluid warming nursing can effectively reduce transfusion requirement and hospitalization days, maintain intraoperative normothermia, and promote postoperative coagulation function in elderly patients undergoing Da Vinci robotic-assisted laparoscopic radical cystectomy

Effect of inspiratory muscle training on hypoxemia in obese patients undergoing painless gastroscopy: protocol for a single-center, double-blind, randomized controlled trial

IntroductionObese patients who undergo painless gastroscopy are particularly prone to suffer from upper airway obstruction, respiratory depression, and subsequent hypoxemia. Despite adequate preoxygenation, the incidence of hypoxemia remains high. Recently, inspiratory muscle training (IMT) has been considered to be a promising strategy to increase respiratory muscle strength and endurance with the attendant improvement of pulmonary function. However, it remains unclear whether IMT is associated with a lower rate of hypoxemia in obese patients during this sedative procedure. This study aims to investigate the effectiveness of IMT used in obese patients who are scheduled for selective painless gastroscopy.Methods and analysisThis prospective, randomized controlled trial (RCT) will enroll 232 obese patients with a body mass index (BMI) of 35–39.9 kg·m−2 who undergo painless gastroscopy at the First Affiliated Hospital of Xiamen University. Subjects will be randomly assigned to two groups with a 1:1 ratio. Participants in both groups will receive IMT for 4 weeks prior to gastroscopy. The intervention group will receive IMT with a load of 30% of the maximal inspiratory pressure (Pi(max)) in the first week, with an increase of 10% per week since the following week, while the counterparts in the control group will not receive any load during the 4-week IMT. The primary outcome is the incidence of hypoxemia during painless gastroscopy. Secondary outcomes include the need for airway maneuvers, blood pressure changes, sleep quality assessment, pro-inflammatory cytokines levels, and monitoring of adverse events.DiscussionsThe outcomes of this study will offer invaluable guidance for the clinical implementation of IMT as a potential non-invasive preventive measure. Additionally, it stands to enrich our comprehension of anesthesia management and airway-related challenges in obese patients undergoing procedural sedation, which we anticipate will further contribute to addressing the turnaround concerns within high-volume, swiftly paced ambulatory endoscopy centers.Ethics and disseminationThis study has been approved by the Ethics Committee of the First Affiliated Hospital of Xiamen University (2022, No.091). The results will be submitted for publication in peer-reviewed journals.Trial registration numberChina Clinical Trial Center (ChiCTR2200067041)