875 research outputs found
Connecting Software Metrics across Versions to Predict Defects
Accurate software defect prediction could help software practitioners
allocate test resources to defect-prone modules effectively and efficiently. In
the last decades, much effort has been devoted to build accurate defect
prediction models, including developing quality defect predictors and modeling
techniques. However, current widely used defect predictors such as code metrics
and process metrics could not well describe how software modules change over
the project evolution, which we believe is important for defect prediction. In
order to deal with this problem, in this paper, we propose to use the
Historical Version Sequence of Metrics (HVSM) in continuous software versions
as defect predictors. Furthermore, we leverage Recurrent Neural Network (RNN),
a popular modeling technique, to take HVSM as the input to build software
prediction models. The experimental results show that, in most cases, the
proposed HVSM-based RNN model has a significantly better effort-aware ranking
effectiveness than the commonly used baseline models
Application of Blind Deblurring Reconstruction Technique to SPECT Imaging
An SPECT image can be approximated as the convolution of the ground truth spatial radioactivity with the system point spread function (PSF). The PSF of an SPECT system is determined by the combined effect of several factors, including the gamma camera PSF, scattering, attenuation, and collimator response. It is hard to determine the SPECT system PSF
analytically, although it may be measured experimentally. We formulated a blind deblurring reconstruction algorithm to
estimate both the spatial radioactivity distribution and the system PSF from the set of blurred projection images. The
algorithm imposes certain spatial-frequency domain constraints on the reconstruction volume and the PSF and does
not otherwise assume knowledge of the PSF. The algorithm alternates between two iterative update sequences that
correspond to the PSF and radioactivity estimations, respectively. In simulations and a small-animal study, the algorithm
reduced image blurring and preserved the edges without introducing extra artifacts. The localized measurement shows
that the reconstruction efficiency of SPECT images improved more than 50% compared to conventional expectation
maximization (EM) reconstruction. In experimental studies, the contrast and quality of reconstruction was substantially
improved with the blind deblurring reconstruction algorithm
WeSinger 2: Fully Parallel Singing Voice Synthesis via Multi-Singer Conditional Adversarial Training
This paper aims to introduce a robust singing voice synthesis (SVS) system to
produce very natural and realistic singing voices efficiently by leveraging the
adversarial training strategy. On one hand, we designed simple but generic
random area conditional discriminators to help supervise the acoustic model,
which can effectively avoid the over-smoothed spectrogram prediction and
improve the expressiveness of SVS. On the other hand, we subtly combined the
spectrogram with the frame-level linearly-interpolated F0 sequence as the input
for the neural vocoder, which is then optimized with the help of multiple
adversarial conditional discriminators in the waveform domain and multi-scale
distance functions in the frequency domain. The experimental results and
ablation studies concluded that, compared with our previous auto-regressive
work, our new system can produce high-quality singing voices efficiently by
fine-tuning different singing datasets covering from several minutes to a few
hours. A large number of synthesized songs with different timbres are available
online https://zzw922cn.github.io/wesinger2 and we highly recommend readers to
listen to them.Comment: accepted at ICASSP 202
Brain MRI Super Resolution Using 3D Deep Densely Connected Neural Networks
Magnetic resonance image (MRI) in high spatial resolution provides detailed
anatomical information and is often necessary for accurate quantitative
analysis. However, high spatial resolution typically comes at the expense of
longer scan time, less spatial coverage, and lower signal to noise ratio (SNR).
Single Image Super-Resolution (SISR), a technique aimed to restore
high-resolution (HR) details from one single low-resolution (LR) input image,
has been improved dramatically by recent breakthroughs in deep learning. In
this paper, we introduce a new neural network architecture, 3D Densely
Connected Super-Resolution Networks (DCSRN) to restore HR features of
structural brain MR images. Through experiments on a dataset with 1,113
subjects, we demonstrate that our network outperforms bicubic interpolation as
well as other deep learning methods in restoring 4x resolution-reduced images.Comment: Accepted by ISBI'1
Prioritization and aggregation of intuitionistic preference relations: A multiplicative- transitivity-based transformation from intuitionistic judgment data to priority weights
Magnetic resonance multitasking for motion-resolved quantitative cardiovascular imaging.
Quantitative cardiovascular magnetic resonance (CMR) imaging can be used to characterize fibrosis, oedema, ischaemia, inflammation and other disease conditions. However, the need to reduce artefacts arising from body motion through a combination of electrocardiography (ECG) control, respiration control, and contrast-weighting selection makes CMR exams lengthy. Here, we show that physiological motions and other dynamic processes can be conceptualized as multiple time dimensions that can be resolved via low-rank tensor imaging, allowing for motion-resolved quantitative imaging with up to four time dimensions. This continuous-acquisition approach, which we name cardiovascular MR multitasking, captures - rather than avoids - motion, relaxation and other dynamics to efficiently perform quantitative CMR without the use of ECG triggering or breath holds. We demonstrate that CMR multitasking allows for T1 mapping, T1-T2 mapping and time-resolved T1 mapping of myocardial perfusion without ECG information and/or in free-breathing conditions. CMR multitasking may provide a foundation for the development of setup-free CMR imaging for the quantitative evaluation of cardiovascular health
p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner.
Bone mass is determined by the balance between bone formation, carried out by mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte-derived osteoclasts. Here we investigated the potential roles of p38 MAPKs, which are activated by growth factors and cytokines including RANKL and BMPs, in osteoclastogenesis and bone resorption by ablating p38α MAPK in LysM+monocytes. p38α deficiency promoted monocyte proliferation but regulated monocyte osteoclastic differentiation in a cell-density dependent manner, with proliferating p38α-/- cultures showing increased differentiation. While young mutant mice showed minor increase in bone mass, 6-month-old mutant mice developed osteoporosis, associated with an increase in osteoclastogenesis and bone resorption and an increase in the pool of monocytes. Moreover, monocyte-specific p38α ablation resulted in a decrease in bone formation and the number of bone marrow mesenchymal stem/stromal cells, likely due to decreased expression of PDGF-AA and BMP2. The expression of PDGF-AA and BMP2 was positively regulated by the p38 MAPK-Creb axis in osteoclasts, with the promoters of PDGF-AA and BMP2 having Creb binding sites. These findings uncovered the molecular mechanisms by which p38α MAPK regulates osteoclastogenesis and coordinates osteoclastogenesis and osteoblastogenesis
Parametric data-parallel architectures for TLM acceleration
We discuss the architecture and
microarchitecture of a scalable, parametric vector
accelerator for the TLM algorithm. Architecture-level
experimentation demonstrates an order of
magnitude complexity reduction for vector
lengths of 16 32-bit single-precision elements. We
envisage the proposed architecture replicated in a
SOC environment thus, forming a multiprocessor
system capable of tapping parallelism at the
thread level as well as the data level
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