468 research outputs found
Pengaruh Implementasi Kebijakan Tambahan Penghasilan Terhadap Motivasi Kerja Pegawai Dinas Kesehatan Provinsi Sulawesi Tengah
This study was conducted to determine how much influence the implementation of additional policies on work motivation income civil servants in Central Sulawesi province. This study uses the theory of Van Meter and Van Horn with standard dimensions and policy objectives, resources, communication between the implementing agency, the implementing body characteristics, social, economic and political, disposition / attitude implementers. The method used in the study is survay analytic using cross sectional design of a study to study the dynamics of the correlation between risk factors by means of observation or data collection approach as well. The results showed that the magnitude of the effect of the implementation of additional policies on work motivation of employees earning the provincial health bureau in Central Sulawesi was the degree of correlation moderate to very low-level relations with the interval of the correlation coefficient between 0.172 up to 0.457
Topological surface electronic states in candidate nodal-line semimetal CaAgAs
We investigate systematically the bulk and surface electronic structure of
the candidate nodal-line semimetal CaAgAs by angle resolved photoemission
spectroscopy and density functional calculations. We observed a metallic,
linear, non--dispersive surface band that coincides with the
high-binding-energy part of the theoretical topological surface state, proving
the topological nontriviality of the system. An overall downshift of the
experimental Fermi level points to a rigid-band-like -doping of the samples,
due possibly to Ag vacancies in the as-grown crystals.Comment: 6 pages, 5 figure
Abundance ratios of OH/CO and HCO+/CO as probes of the cosmic ray ionization rate in diffuse clouds
The cosmic-ray ionization rate (CRIR, ) is one of the key parameters
controlling the formation and destruction of various molecules in molecular
clouds. However, the current most commonly used CRIR tracers, such as H,
OH, and HO, are hard to detect and require the presence of
background massive stars for absorption measurements. In this work, we propose
an alternative method to infer the CRIR in diffuse clouds using the abundance
ratios of OH/CO and HCO/CO. We have analyzed the response of chemical
abundances of CO, OH, and HCO on various environmental parameters of the
interstellar medium in diffuse clouds and found that their abundances are
proportional to . Our analytic expressions give an excellent
calculation of the abundance of OH for 10 s,
which are potentially useful for modelling chemistry in hydrodynamical
simulations. The abundances of OH and HCO were found to monotonically
decrease with increasing density, while the CO abundance shows the opposite
trend. With high-sensitivity absorption transitions of both CO (1--0) and
(2--1) lines from ALMA, we have derived the H number densities () toward 4 line-of-sights (LOSs); assuming a kinetic temperature of
, we find a range of
(0.140.03--1.20.1)10 cm}. By comparing the
observed and modelled HCO/CO ratios, we find that in our diffuse
gas sample is in the { range of 10 10 s. This is 2 times higher
than the average value measured at higher extinction, supporting an attenuation
of CRs as suggested by theoretical models.Comment: 22 pages, 9 figures, accepted by Ap
Dependence of Chemical Abundance on the Cosmic Ray Ionization Rate in IC 348
Ions (e.g., H, HO) have been used extensively to quantify the
cosmic-ray ionization rate (CRIR) in diffuse sightlines. However, measurements
of CRIR in low-to-intermediate density gas environments are rare, especially
when background stars are absent. In this work, we combine molecular line
observations of CO, OH, CH, and HCO in the star-forming cloud IC~348, and
chemical models to constrain the value of CRIR and study the response of the
chemical abundances distribution. The cloud boundary is found to have an
of approximately 4 mag. From the interior to the exterior of the
cloud, the observed CO line intensities drop by an order of magnitude.
The calculated average abundance of CO (assuming C/C = 65)
is (1.20.9) 10, which increases by a factor of 6 from the
interior to the outside regions. The average abundance of CH (3.30.7
10) is in good agreement with previous findings in diffuse and
translucent clouds ( 5 mag). However, we did not find a decline
in CH abundance in regions of high extinction (8 mag) as
previously reported in Taurus. By comparing the observed molecular abundances
and chemical models, we find a decreasing trend of CRIR as
increases. The inferred CRIR of = (4.71.5)
10 s at low is consistent with H measurements
toward two nearby massive stars.Comment: 21 pages, 11 figures. Submitted to Ap
REST: A Toolkit for Resting-State Functional Magnetic Resonance Imaging Data Processing
Resting-state fMRI (RS-fMRI) has been drawing more and more attention in recent years. However, a publicly available, systematically integrated and easy-to-use tool for RS-fMRI data processing is still lacking. We developed a toolkit for the analysis of RS-fMRI data, namely the RESting-state fMRI data analysis Toolkit (REST). REST was developed in MATLAB with graphical user interface (GUI). After data preprocessing with SPM or AFNI, a few analytic methods can be performed in REST, including functional connectivity analysis based on linear correlation, regional homogeneity, amplitude of low frequency fluctuation (ALFF), and fractional ALFF. A few additional functions were implemented in REST, including a DICOM sorter, linear trend removal, bandpass filtering, time course extraction, regression of covariates, image calculator, statistical analysis, and slice viewer (for result visualization, multiple comparison correction, etc.). REST is an open-source package and is freely available at http://www.restfmri.net
Recommended from our members
A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response.
The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes. We conducted a targeted MHC sequencing in 40 Cantonese NPC patients followed by a two-stage replication in 1065 NPC cases and 2137 controls of Southern Chinese descendent. Quantitative RT-PCR analysis (qRT-PCR) was used to detect gene expression status in 108 NPC and 43 noncancerous nasopharyngeal (NP) samples. Luciferase reporter assay and chromatin immunoprecipitation (ChIP) were used to assess the transcription factor binding site. We discovered that a novel SNP rs117565607_A at TRIM26 displayed the strongest association (OR = 1.909, Pcombined = 2.750 × 10-19 ). We also observed that TRIM26 was significantly downregulated in NPC tissue samples with genotype AA/AT than TT. Immunohistochemistry (IHC) test also found the TRIM26 protein expression in NPC tissue samples with the genotype AA/AT was lower than TT. According to computational prediction, rs117565607 locus was a binding site for the transcription factor Yin Yang 1 (YY1). We observed that the luciferase activity of YY1 which is binding to the A allele of rs117565607 was suppressed. ChIP data showed that YY1 was binding with T not A allele. Significance analysis of microarray suggested that TRIM26 downregulation was related to low immune response in NPC. We have identified a novel gene TRIM26 and a novel SNP rs117565607_A associated with NPC risk by regulating transcriptional process and established a new functional link between TRIM26 downregulation and low immune response in NPC
- …