Advances in the Application of Chromatographic Techniques in Forensic Toxicology Fund

With the gradual advancement of knowledge and civilization, forensic science and technology is steadily developing and evolving. Chromatography, as an important analytical technique with the advantages of simplicity, rapidity and high sensitivity, has been widely used by researchers in various countries in the process of detecting toxic substances and drugs in forensic science. This paper presents a comprehensive analysis and exploration of chromatographic techniques from three perspectives: the development of chromatography, its classification according to the two-phase state, chromatographic separation mechanism and the nature of the stationary phase, and the applications of chromatographic techniques. The future development trend of chromatographic analysis technology is also prospected in order to provide new ideas for the development and research2o2f other technologies in thefield of forensic science

High-mobility graphene on liquid p-block elements by ultra-low-loss CVD growth

The high-quality and low-cost of the graphene preparation method decide whether graphene is put into the applications finally. Enormous efforts have been devoted to understand and optimize the CVD process of graphene over various d-block transition metals (e.g. Cu, Ni and Pt). Here we report the growth of uniform high-quality single-layer, single-crystalline graphene flakes and their continuous films over p-block elements (e.g. Ga) liquid films using ambient-pressure chemical vapor deposition. The graphene shows high crystalline quality with electron mobility reaching levels as high as 7400 cm2 V−1s−1 under ambient conditions. Our employed growth strategy is ultra-low-loss. Only trace amounts of Ga are consumed in the production and transfer of the graphene and expensive film deposition or vacuum systems are not needed. We believe that our research will open up new territory in the field of graphene growth and thus promote its practical application

Real-Time Precise Orbit Determination for LEO between Kinematic and Reduced-Dynamic with Ambiguity Resolution

The real-time integer-ambiguity resolution of the carrier-phase observation is one of the most effective approaches to enhance the accuracy of real-time precise point positioning (PPP), kinematic precise orbit determination (KPOD), and reduced-dynamic precise orbit determination (RPOD) for low earth orbit (LEO) satellites. In this study, the integer phase clock (IPC) and wide-lane satellite bias (WSB) products from CNES (Centre National d’Etudes Spatiales) are used to fix ambiguity in real time. Meanwhile, the three models of real-time PPP, KPOD, and RPOD are applied to validate the contribution of ambiguity resolution. Experimental results show that (1) the average positioning accuracy of IGS stations for ambiguity-fixed solutions is improved from about 7.14 to 5.91 cm, with an improvement of around 17% compared to the real-time float PPP solutions, with enhancement in the east-west direction particularly significant, with an improvement of about 29%; (2) the average accuracy of the estimated LEO orbit with ambiguity-fixed solutions in the real-time KPOD and RPOD mode is improved by about 16% and 10%, respectively, with respect to the corresponding mode with the ambiguity-float solutions; (3) the performance of real-time LEO RPOD is better than that of the corresponding KPOD, regardless of fixed- or float-ambiguity solutions. Moreover, the average ambiguity-fixed ratio can reach more than 90% in real-time PPP, KPOD, and RPO

Global monitoring of ionospheric weather by GIRO and GNSS data fusion

Prompt and accurate imaging of the ionosphere is essential to space weather services, given a broad spectrum of applications that rely on ionospherically propagating radio signals. As the 3D spatial extent of the ionosphere is vast and covered only fragmentarily, data fusion is a strong candidate for solving imaging tasks. Data fusion has been used to blend models and observations for the integrated and consistent views of geosystems. In space weather scenarios, low latency of the sensor data availability is one of the strongest requirements that limits the selection of potential datasets for fusion. Since remote plasma sensing instrumentation for ionospheric weather is complex, scarce, and prone to unavoidable data noise, conventional 3D-var assimilative schemas are not optimal. We describe a novel substantially 4D data fusion service based on near-real-time data feeds from Global Ionosphere Radio Observatory (GIRO) and Global Navigation Satellite System (GNSS) called GAMBIT (Global Assimilative Model of the Bottomside Ionosphere with Topside estimate). GAMBIT operates with a few-minute latency, and it releases, among other data products, the anomaly maps of the effective slab thickness (EST) obtained by fusing GIRO and GNSS data. The anomaly EST mapping aids understanding of the vertical plasma restructuring during disturbed conditionsPeer ReviewedPostprint (published version

The cooperative IGS RT-GIMs: a reliable estimation of the global ionospheric electron content distribution in real time

The Real-Time Working Group (RTWG) of the International GNSS Service (IGS) is dedicated to providing high-quality data and high-accuracy products for Global Navigation Satellite System (GNSS) positioning, navigation, timing and Earth observations. As one part of real-time products, the IGS combined Real-Time Global Ionosphere Map (RT-GIM) has been generated by the real-time weighting of the RT-GIMs from IGS real-time ionosphere centers including the Chinese Academy of Sciences (CAS), Centre National d'Etudes Spatiales (CNES), Universitat Politècnica de Catalunya (UPC) and Wuhan University (WHU). The performance of global vertical total electron content (VTEC) representation in all of the RT-GIMs has been assessed by VTEC from Jason-3 altimeter for 3 months over oceans and dSTEC-GPS technique with 2¿d observations over continental regions. According to the Jason-3 VTEC and dSTEC-GPS assessment, the real-time weighting technique is sensitive to the accuracy of RT-GIMs. Compared with the performance of post-processed rapid global ionosphere maps (GIMs) and IGS combined final GIM (igsg) during the testing period, the accuracy of UPC RT-GIM (after the improvement of the interpolation technique) and IGS combined RT-GIM (IRTG) is equivalent to the rapid GIMs and reaches around 2.7 and 3.0 TECU (TEC unit, 1016¿el¿m-2) over oceans and continental regions, respectively. The accuracy of CAS RT-GIM and CNES RT-GIM is slightly worse than the rapid GIMs, while WHU RT-GIM requires a further upgrade to obtain similar performance. In addition, a strong response to the recent geomagnetic storms has been found in the global electron content (GEC) of IGS RT-GIMs (especially UPC RT-GIM and IGS combined RT-GIM). The IGS RT-GIMs turn out to be reliable sources of real-time global VTEC information and have great potential for real-time applications including range error correction for transionospheric radio signals, the monitoring of space weather, and detection of natural hazards on a global scale. All the IGS combined RT-GIMs generated and analyzed during the testing period are available at https://doi.org/10.5281/zenodo.5042622 (Liu et al., 2021b).his research has been supported by the China Scholarship Council (CSC). The contribution from UPC- IonSAT authors was partially supported by the European Union- funded project PITHIA-NRF (grant no. 101007599) and by the ESSP/ICAO-funded project TEC4SpaW. The work of An- drzej Krankowski is supported by the National Centre for Research and Development, Poland, through grant ARTEMIS (grant nos. DWM/PL-CHN/97/2019 and WPC1/ARTEMIS/2019)Peer ReviewedPostprint (published version

Consistency of seven different GNSS global ionospheric mapping techniques during one solar cycle

In the context of the International GNSS Service (IGS), several IGS Ionosphere Associated Analysis Centers (IAAC) have developed different techniques to provide Global Ionospheric Maps (GIMs) of Vertical Total Electron Content (VTEC) since 1998. In this paper we present a comparison of the performances of all the GIMs created in the frame of IGS. Indeed we compare the classical ones (for the ionospheric analysis centers CODE, ESA/ESOC, JPL and UPC) with the new ones (NRCAN, CAS, UWH). To assess the qual- ity of them in fair and completely independent ways, two assessment meth- ods are used: a direct comparison to altimeter data (VTEC-altimeter) and to the difference of slant total electron content (STEC) observed in independent ground reference stations (dSTEC-GPS). The main conclusion of this study, performed during one solar cycle, is the consistency of the results between so many different GIM techniques and implementations

St. Patrick’s Day 2015 geomagnetic storm analysis based on Real Time Ionosphere Monitoring

A detailed analysis is presented for the days in March, 2015 surrounding St. Patrick’s Day 2015 geomagnetic storm, based on the existing real-time and near real-time ionospheric models (global or regional) within the group, which are mainly based on Global Navigation Satellite Systems (GNSS) and ionosonde data. For this purpose, a variety of ionospheric parameters is considered, including Total Electron Content (TEC), F2 layer critical frequency (foF2), F2 layer peak (hmF2), bottomside halfthickness (B0) and ionospheric disturbance W-index. Also, ionospheric high-frequency perturbations such as Travelling Ionospheric Disturbances (TIDs), scintillations and the impact of solar flares facing the Earth will be presented to derive a clear picture of the ionospheric dynamicsPostprint (published version

Quality assessment of GPS, Galileo and BeiDou-2/3 satellite broadcast group delays

The quality of broadcast group delays (BGDs) transmitted in the navigation messages of the Global Positioning System (GPS), BeiDou-2/3 and Galileo is assessed by comparison with multi-GNSS differential code bias (DCB) products generated at the Chinese Academy of Sciences (CAS). An automatic DCB (AutoDCB) realignment procedure is presented to handle discontinuities within individual BGD/DCB series. The analysis is performed over a four-year period starting from January 2014. For GPS, the consistency between broadcast timing group delays (TGDs) and CAS MGEX DCBs is 0.25 ns, and the corresponding values are 0.05, 0.3 and 0.45 ns for L1C/A, L2C and L5Q inter-signal corrections (ISCs), respectively. The best agreement between GPS L2C ISCs and CAS MGEX C1W-C2L DCBs is emphasized. The inconsistency between broadcast and post-processed C2I-C6I DCBs (=TGD1) is found to decrease from 1.5 to 0.45 ns across the entire BeiDou-2 constellation since late July 2017, indicating a significant quality improvement of BeiDou-2 transmitted TGD1 parameters. A systematic offset of around 4.0 ns is found between TGD1 reference datums of BeiDou-3 and BeiDou-2 constellations, which needs to be removed in the combined BeiDou-2/3 B1I single-frequency or B1I+B3I dual-frequency standard positioning applications. Aside from the increasingly improved repeatability of broadcast E1-E5a/5b delays, an overall agreement at the level of 0.1-0.4 ns is achieved between Galileo transmitted value and DCB metadata from European GNSS Agency (GSA) for the in-orbit validation (IOV) satellites. In the comparison of Galileo BGDs and CAS MGEX DCBs, the consistency is at the level of 0.4 and 0.3 ns for IOV and full operation capability (FOC) satellites, respectively. The requirement of the routine assessment of broadcast group delays is also emphasized, in particular for newly launched satellites of new constellations