Energy storage salt cavern construction and evaluation technology

With the demand for peak-shaving of renewable energy and the approach of carbon peaking and carbon neutrality goals, salt caverns are expected to play a more effective role in oil and gas storage, compressed air energy storage, large-scale hydrogen storage, and temporary carbon dioxide storage. In order to effectively utilize the underground space of salt mines on a sound scientific basis, the construction of salt caverns for energy storage should implement the maximum utilization of salt layers, improve the cavern construction efficiency, shorten the construction period, and ensure cavern safety. In this work, built upon design experience and on-site practice in salt cavern gas storage, the four pivotal construction stages-conceptual design, solution mining simulation, tightness assessment, and stability evaluation-have been thoroughly enhanced, strengthening the technical framework for salt cavern energy storage.Document Type: PerspectiveCited as: Wan, J., Meng, T., Li, J., Liu, W. Energy storage salt cavern construction and evaluation technology. Advances in Geo-Energy Research, 2023, 9(3): 141-145. https://doi.org/10.46690/ager.2023.09.0

Causal SAR ATR with Limited Data via Dual Invariance

Synthetic aperture radar automatic target recognition (SAR ATR) with limited data has recently been a hot research topic to enhance weak generalization. Despite many excellent methods being proposed, a fundamental theory is lacked to explain what problem the limited SAR data causes, leading to weak generalization of ATR. In this paper, we establish a causal ATR model demonstrating that noise $N$ that could be blocked with ample SAR data, becomes a confounder with limited data for recognition. As a result, it has a detrimental causal effect damaging the efficacy of feature $X$ extracted from SAR images, leading to weak generalization of SAR ATR with limited data. The effect of $N$ on feature can be estimated and eliminated by using backdoor adjustment to pursue the direct causality between $X$ and the predicted class $Y$. However, it is difficult for SAR images to precisely estimate and eliminated the effect of $N$ on $X$. The limited SAR data scarcely powers the majority of existing optimization losses based on empirical risk minimization (ERM), thus making it difficult to effectively eliminate $N$'s effect. To tackle with difficult estimation and elimination of $N$'s effect, we propose a dual invariance comprising the inner-class invariant proxy and the noise-invariance loss. Motivated by tackling change with invariance, the inner-class invariant proxy facilitates precise estimation of $N$'s effect on $X$ by obtaining accurate invariant features for each class with the limited data. The noise-invariance loss transitions the ERM's data quantity necessity into a need for noise environment annotations, effectively eliminating $N$'s effect on $X$ by cleverly applying the previous $N$'s estimation as the noise environment annotations. Experiments on three benchmark datasets indicate that the proposed method achieves superior performance

N-acetylcysteine Protects against Apoptosis through Modulation of Group I Metabotropic Glutamate Receptor Activity

The activation of group I metabotropic glutamate receptor (group I mGlus) has been shown to produce neuroprotective or neurotoxic effects. In this study, we investigated the effects of N-acetylcysteine (NAC), a precursor of the antioxidant glutathione, on group I mGlus activation in apoptosis of glial C6 and MN9D cell lines, and a rat model of Parkinson's disease (PD). We demonstrated that NAC protected against apoptosis through modulation of group I mGlus activity. In glial C6 cells, NAC promoted phosphorylation of ERK induced by (s)-3,5- dihydroxy-phenylglycine (DHPG), an agonist of group I mGlus. NAC enhanced the group I mGlus-mediated protection from staurosporine (STS)-induced apoptosis following DHPG treatment. Moreover, in rotenone-treated MN9D cells and PD rat model, NAC protected against group I mGlus-induced toxicity by compromising the decrease in phosphorylation of ERK, phosphorylation or expression level of TH. Furthermore, the results showed that NAC prohibited the level of ROS and oxidation of cellular GSH/GSSG (Eh) accompanied by activated group I mGlus in the experimental models. Our results suggest that NAC might act as a regulator of group I mGlus-mediated activities in both neuroprotection and neurotoxicity via reducing the oxidative stress, eventually to protect cell survival. The study also suggests that NAC might be a potential therapeutics targeting for group I mGlus activation in the treatment of PD

Effects of hyperbaric oxygen on vascular endothelial function in patients with slow coronary flow

   Background: To improve therapy for slow coronary flow (SCF), the effects of hyperbaric oxygen (HBO) therapy on vascular endothelial function in SCF patients is the focus of this investigation. Methods: Ninety-eight patients who exhibited chest discomfort were retrospectively analyzed, and di­agnosed with SCF by coronary artery angiography at the Third Hospital of Hebei Medical University, Shijiazhuang, China from 2014 to 2016. The patients were divided into two groups according to the following treatment: HBO group (n = 48) and the control group (n = 50). Patients in the control group were administrated with conventional treatment, while those in the HBO group were administrated HBO therapy for 4 weeks in addition to conventional treatment. To evaluate the effects of HBO on vas­cular endothelial functions, plasma levels of nitric oxide (NO), calcitonin gene-related peptide (CGRP), endothelin-1 (ET-1), high sensitivity C-reactive protein (hsCRP) as well as endothelial-dependent flow-mediated vasodilation (FMD) of the brachial artery were measured in both groups before and after their respective treatments. Results: There were no significant differences in plasma levels of NO, ET-1, CGRP, hsCRP nor in FMD measurements between the two groups before treatment (p > 0.05). Moreover, the levels of all the parameters measured showed no significant changes before and after treatment in the control group. However, when comparing the control group, FMD and plasma NO and CGRP levels were significantly increased in the HBO group after treatment (p < 0.01), whereas hsCRP and ET-1 levels decreased dramatically (p < 0.001). Conclusions: The HBO treatment in addition to conventional therapy may significantly improve the vascular endothelial function in SCF patients. (Cardiol J 2018; 25, 1: 106–112

Compressed air energy storage in salt caverns in China: Development and outlook

With the promotion of China’s carbon peaking and carbon neutrality goals, the energy industry is transforming from traditional fossil energy to renewable energy, which is sustainable, clean and safe. The development of renewable energy is not only an important measure to achieve the above goals but also a significant factor to alleviate the global energy crisis. Salt caverns, with good air tightness, have been considered as the best choice for large-scale underground energy storage. To elaborate on the research and future development of salt cavern compressed air energy storage technology in China, this paper analyzes the mode and characteristics of compressed air energy storage, explores the current development, key technologies and engineering experience of the construction of underground salt caverns for compressed air energy storage at home and abroad. Focusing on salt cavern compressed air energy storage technology, this paper provides a deep analysis of large-diameter drilling and completion, solution mining and morphology control, and evaluates the factors affecting cavern tightness and wellbore integrity. The future development and challenges of underground salt caverns for compressed air energy storage in China are discussed, and the prospects for the three key technologies of large-diameter drilling and completion and wellbore integrity, solution mining morphology control and detection, and tubing corrosion and control are considered. This paper aims to provide a useful reference for the development of underground salt cavern compressed air energy storage technology, the transformation of green and renewable energy, and the realization of carbon neutral vision.Document Type: Invited reviewCited as: Wan, M., Ji, W., Wan, J., He, Y., Li, J., Liu, W., Jurado, M. J. Compressed air energy storage in salt caverns in China: Development and outlook. Advances in Geo-Energy Research, 2023, 9(1): 54-67. https://doi.org/10.46690/ager.2023.07.0

Identification of forensically significant beetles (Coleoptera: Staphylinoidae) based on COI gene in China

_________________________________________________________________________________________ Abstract: Accurate and fast identification of insect species is an initial and crucial step of using entomological evidence in forensic cases. Beetles of Coleoptera usually take large parts of taxonomic composition of the carrion-arthropod community and have important meaning for the estimation of postmortem interval (PMI). Traditional morphological taxonomy of beetles poses a great challenge for forensic investigators without entomological background. A cytochrome oxidase subunits one (COI) sequence on mitochondrial DNA with 816-bp length was studied for molecular identification of forensic significant beetles. Six beetle species in superfamily Staphylinoidae collected from four locations in China were sampled. All species were successfully separated with high support value, which indicated this partial COI fragment was sufficient for distinguishing these beetles. Further step utilization of COI fragment in identification of forensically important beetles was also discussed. Key Words: forensic entomology; coleoptera; staphylinoidae; specie identification; cytochrome oxidase subunits one F orensic entomology is the study of insects and other arthropods, being used to solve litigation in civil and criminal cases. The value of forensic entomology for postmortem interval (PMI) in practical forensic work has been well demonstrated in many case studies Actually, the duration of early instars on carrion is generally longer in Coleoptera than that of Diptera The potential of beetles in investigation of forensic case and research work has been discussed in a few articles published recently, usually including beetle species from family Staphylinidae (rove beetles

Cardiac tamponade, a rare complication of gastric cardia cancer resection after neoadjuvant chemotherapy combined with immunotherapy: a case report and literature review

Transthoracic cardia resection is a technically well-established surgical procedure. However, acute cardiac tamponade in the early postoperative period is extremely rare. The occurrence is life-threatening to the patient. It also poses a great clinical challenge for perioperative management. To date, few cases of pericardial tamponade have been reported in gastric cancer resection performed after neoadjuvant chemotherapy combined with immunotherapy. We present the case of a 62-year-old woman who received neoadjuvant chemotherapy combined with immunotherapy before surgery, followed by transthoracic surgery. A life-threatening complication, pericardial tamponade, occurred in the early postoperative period. The successful outcome was achieved in through multidisciplinary collaboration