An Executive Summary of Deep Change

http://deepblue.lib.umich.edu/bitstream/2027.42/100225/1/MBA_Levine_Fall_1998Final.pd

An Executive summary of deep change

http://deepblue.lib.umich.edu/bitstream/2027.42/96911/1/MBA_LevineF_1998Final.pd

The Deep change workbook

http://deepblue.lib.umich.edu/bitstream/2027.42/96912/1/MBA_LevineSu_1998aFinal.pd

Tents along the Merrimack: Homelessness and University-Community Cooperation

This article presents historical, institutional, and ethical contexts for a university and an industrial, ethnic community\u27s cooperative effort to address local hunger and homelessness. A large portion of the University of Massachusetts at Lowell\u27s students are of working-class and local origin. Neighborhood social problems are in effect their own, and community service may be considered a variant of self-help. Attention is paid the special importance of developing a sense of community across traditional boundaries on and off campus and to the establishment of permanent mutually beneficial structures

Global Carbon Emissions in the Coming Decades: The Case of China

China's annual energy-related carbon emissions surpassed those of the United States in In order to build a more robust understanding of China's energy-related carbon emissions, emissions after 2001? The divergence between actual and forecasted carbon emissions international trade, and central government policies in driving emissions growth. so greatly in error and what drove the rapid growth of China's energy-related carbon this article reviews the role of economic restructuring, urbanization, coal dependence, underscores the rapid changes that have taken place in China's energy system since 2001

Chapter 2: Sustainable and Unsustainable Developments in the U.S. Energy System

Over the course of the nineteenth and twentieth centuries, the United States developed a wealthy society on the basis of cheap and abundant fossil fuel energy. As fossil fuels have become ecologically and economically expensive in the twenty-first century, America has shown mixed progress in transitioning to a more sustainable energy system. From 2000 to 2006, energy and carbon intensity of GDP continued favorable long-term trends of decline. Energy end-use efficiency also continued to improve; for example, per-capita electricity use was 12.76 MWh per person per year in 2000 and again in 2006, despite 16 percent GDP growth over that period. Environmental costs of U.S. energy production and consumption have also been reduced, as illustrated in air quality improvements. However, increased fossil fuel consumption, stagnant efficiency standards, and expanding corn-based ethanol production have moved the energy system in the opposite direction, toward a less sustainable energy system. This chapter reviews energy system developments between 2000 and 2006 and presents policy recommendations to move the United States toward a more sustainable energy system

Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors.

Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies. Here, we evaluated for differential gene expression (DGE) in peripheral blood between breast cancer survivors with and without PIPN and for neuroinflammatory (NI) related signaling pathways and whole-transcriptome profiles from other experiments. Pathway impact analysis identified 8 perturbed NI related pathways. Expression profile analysis found 15 experiments having similar whole-transcriptome profiles of DGE related to neuroinflammation and PIPN. These findings suggest that perturbations in pathways associated with neuroinflammation are found in cancer survivors with PIPN

CONDUIT: A New Multidisciplinary Integration Environment for Flight Control Development

A state-of-the-art computational facility for aircraft flight control design, evaluation, and integration called CONDUIT (Control Designer's Unified Interface) has been developed. This paper describes the CONDUIT tool and case study applications to complex rotary- and fixed-wing fly-by-wire flight control problems. Control system analysis and design optimization methods are presented, including definition of design specifications and system models within CONDUIT, and the multi-objective function optimization (CONSOL-OPTCAD) used to tune the selected design parameters. Design examples are based on flight test programs for which extensive data are available for validation. CONDUIT is used to analyze baseline control laws against pertinent military handling qualities and control system specifications. In both case studies, CONDUIT successfully exploits trade-offs between forward loop and feedback dynamics to significantly improve the expected handling, qualities and minimize the required actuator authority. The CONDUIT system provides a new environment for integrated control system analysis and design, and has potential for significantly reducing the time and cost of control system flight test optimization