69 research outputs found
The inhibition of growth and development of Ascaris suum larvae in vitro by proline analogs
Isolation and characterization of the cuticle from the free-living nematode Panagrellus silusiae
Adult Paratesticular Rhabdomyosarcoma Presenting as Acute Intestinal Obstruction—A Case Report
Cuticle preparations from Necator americanus and their immunogenicity in the infected host.
Cuticle samples have been prepared from the human parasitic nematode Necator americanus using detergent solubilisation with sodium dodecyl sulphate and subsequent reduction of disulphide bonds using 2-beta-mercaptoethanol. It would appear that N. americanus, like many other nematodes, relies on relatively small collagenous proteins, linked by disulphide bonds, to maintain the integrity of its cuticle. These molecules are normally hidden from the immune system during the course of infection but are potentially immunogenic. It is suggested that waves of antibodies, firstly with specificity against superficial cuticular epitopes followed by antibodies against deeper lying, structural elements, should be induced during vaccination to effectively destroy the nematode at the cuticular level
Ascaris lumbricoides: Characterization of the collagenous components of the adult cuticle
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