345 research outputs found
Ion specific effects on phase transitions in protein solutions
A recent Monte Carlo simulation determined the potential of mean force
between two lysozyme molecules in various aqueous solutions [M. Lund et al.
Phys. Rev. Lett. 100, 258105 (2008)]. The study involved a combination of
explicit solvent and continuum model simulations and showed that there are
significant ion-specific protein-protein interactions due to hydrophobic
patches on the protein surfaces. In this paper we use the results of their
study to determine the phase diagram for lysozyme for aqueous solutions of NaCl
and NaI. Two of the three phase diagrams have a stable fluid-fluid critical
point, while the third has a slightly metastable critical point. This results
from a secondary extremum in the potential associated with a repulsive
interaction. This repulsive interaction reduces the effective range of the
attractive interaction and produces a metastable critical point. We compare the
results of one of these phase diagrams with that for a model that includes
ion-dispersion forces, but does not contain solvent structural effects.Comment: 9 figure files + 1 tex fil
New Candidate Interstellar Particle in Stardust IS Aerogel Collector: Analysis by STXM and Ptychography
The Stardust Interstellar Preliminary Examination (ISPE) reported in 2014 the discovery of 7 probable contemporary interstellar (IS) particles captured in Stardust IS Collector aerogel and foils. The ISPE reports represented work done over 6 years by more than 60 scientists and >30,000 volunteers, which emphasizes the challenge identifying and analyzing Stardust IS samples was far beyond the primary Stardust cometary collection. We present a new potentially interstellar particle resulting from a continuation of analyses of the IS aerogel collection
Si-compatible candidates for high-K dielectrics with the Pbnm perovskite structure
We analyze both experimentally (where possible) and theoretically from
first-principles the dielectric tensor components and crystal structure of five
classes of Pbnm perovskites. All of these materials are believed to be stable
on silicon and are therefore promising candidates for high-K dielectrics. We
also analyze the structure of these materials with various simple models,
decompose the lattice contribution to the dielectric tensor into force constant
matrix eigenmode contributions, explore a peculiar correlation between
structural and dielectric anisotropies in these compounds and give phonon
frequencies and infrared activities of those modes that are infrared-active. We
find that CaZrO_3, SrZrO_3, LaHoO_3, and LaYO_3 are among the most promising
candidates for high-K dielectrics among the compounds we considered.Comment: 17 pages, 9 figures, 4 tables. Supplementary information:
http://link.aps.org/supplemental/10.1103/PhysRevB.82.064101 or
http://www.physics.rutgers.edu/~sinisa/highk/supp.pd
Superconducting properties of nanocrystalline MgB thin films made by an in situ annealing process
We have studied the structural and superconducting properties of MgB thin
films made by pulsed laser deposition followed by in situ annealing. The
cross-sectional transmission electron microscopy reveals a nanocrystalline
mixture of textured MgO and MgB with very small grain sizes. A
zero-resistance transition temperature () of 34 K and a zero-field
critical current density () of A/cm were obtained.
The irreversibility field was 8 T at low temperatures, although severe
pinning instability was observed. These bulk-like superconducting properties
show that the in situ deposition process can be a viable candidate for MgB
Josephson junction technologies
Synthesis and Properties of c-axis Oriented Epitaxial MgB2 Thin Films
We report the growth and properties of epitaxial MgB2 thin films on (0001)
Al2O3 substrates. The MgB2 thin films were prepared by depositing boron films
via RF magnetron sputtering, followed by a post-deposition anneal at 850C in
magnesium vapor. X-ray diffraction and cross-sectional TEM reveal that the
epitaxial MgB2 films are oriented with their c-axis normal to the (0001) Al2O3
substrate and a 30 degree rotation in the ab-plane with respect to the
substrate. The critical temperature was found to be 35 K and the anisotropy
ratio, Hc2(parallel to the film) / Hc2(pendicular to the film), about 3 at 25K.
The critical current densities at 4.2 K and 20 K (at 1 T perpendicular magnetic
field) are 5x10E6 A/cm2 and 1x10E6 A/cm2, respectively. The controlled growth
of epitaxial MgB2 thin films opens a new avenue in both understanding
superconductivity in MgB2 and technological applications.Comment: 10 pages, 6 figure
Pressure Tuning of the Charge Density Wave in the Halogen-Bridged Transition-Metal (MX) Solid
We report the pressure dependence up to 95 kbar of Raman active stretching
modes in the quasi-one-dimensional MX chain solid . The data
indicate that a predicted pressure-induced insulator-to-metal transition does
not occur, but are consistent with the solid undergoing either a
three-dimensional structural distortion, or a transition from a charge-density
wave to another broken-symmetry ground state. We show that such a transition
cacan be well-modeled within a Peierls-Hubbard Hamiltonian. 1993 PACS:
71.30.+h, 71.45.Lr, 75.30.Fv, 78.30.-j, 81.40.VwComment: 4 pages, ReVTeX 3.0, figures available from the authors on request
(Gary Kanner, [email protected]), to be published in Phys Rev B Rapid
Commun, REVISION: minor typos corrected, LA-UR-94-246
A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO)
Rationale Mandibular advancement devices (MADs)
are used to treat obstructive sleep apnoea-hypopnoea
syndrome (OSAHS) but evidence is lacking regarding
their clinical and cost-effectiveness in less severe disease.
Objectives To compare clinical- and cost-effectiveness
of a range of MADs against no treatment in mild to
moderate OSAHS.
Measurements and methods This open-label,
randomised, controlled, crossover trial was undertaken at
a UK sleep centre. Adults with Apnoea-Hypopnoea Index
(AHI) 5–<30/h and Epworth Sleepiness Scale (ESS) score
≥9 underwent 6 weeks of treatment with three nonadjustable
MADs: self-moulded (SleepPro 1; SP1);
semi-bespoke (SleepPro 2; SP2); fully-bespoke MAD
(bMAD); and 4 weeks no treatment. Primary outcome
was AHI scored by a polysomnographer blinded to
treatment. Secondary outcomes included ESS, quality of
life, resource use and cost.
Main results 90 patients were randomised and 83
were analysed. All devices reduced AHI compared with
no treatment by 26% (95% CI 11% to 38%, p=0.001)
for SP1, 33% (95% CI 24% to 41%) for SP2 and 36%
(95% CI 24% to 45%, p<0.001) for bMAD. ESS was
1.51 (95% CI 0.73 to 2.29, p<0.001, SP1) to 2.37
(95% CI 1.53 to 3.22, p<0.001, bMAD) lower than no
treatment (p<0.001 for all). Compliance was lower for
SP1, which was the least preferred treatment at trial exit.
All devices were cost-effective compared with no
treatment at a £20 000/quality-adjusted life year (QALY)
threshold. SP2 was the most cost-effective up to
£39 800/QALY.
Conclusions Non-adjustable MADs achieve clinically
important improvements in mild to moderate OSAHS and
are cost-effective
In situ epitaxial MgB2 thin films for superconducting electronics
A thin film technology compatible with multilayer device fabrication is
critical for exploring the potential of the 39-K superconductor magnesium
diboride for superconducting electronics. Using a Hybrid Physical-Chemical
Vapor Deposition (HPCVD) process, it is shown that the high Mg vapor pressure
necessary to keep the MgB phase thermodynamically stable can be achieved
for the {\it in situ} growth of MgB thin films. The films grow epitaxially
on (0001) sapphire and (0001) 4H-SiC substrates and show a bulk-like of
39 K, a (4.2K) of A/cm in zero field, and a
of 29.2 T in parallel magnetic field. The surface is smooth with a
root-mean-square roughness of 2.5 nm for MgB films on SiC. This deposition
method opens tremendous opportunities for superconducting electronics using
MgB
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