1,031 research outputs found
Rising tides? Data capture, platform accumulation, and new monopolies in the digital music economy
This article examines the roles of platform-based distribution and user data in the digital music economy. Drawing on trade press, newspaper coverage, and a consumer privacy complaint, we offer a critical analysis of tech-music partnerships forged between Samsung and Jay-Z (2013), Apple iTunes Store and U2 (2014), Tidal and Kanye West (2016), and Apple Music and Drake (2017). In these cases, information technology (IT) companies supported album releases, and music was used to generate user data and attention: logics of data and attention capture were interwoven. The IT and music industries have adapted their business strategies to what we conceptualize as platform-based capital accumulation or âplatform accumulationâ, and models centred on controlling access and extracting rent have enabled the emergence of new monopolies and IT gatekeepers
Environmental Mental Models of College Students
Primary and secondary students in the United States are provided environmental education in their curricula due in part to national legislation, but higher education, for many U.S. citizens, is the last opportunity to educate young adults about the environment and humansâ role in it in a formalized setting. Pre-college education and other life experiences or ways of learning can shape a studentâs mental model of the environment. While some previous research has focused on understanding environmental mental models of primary and secondary students, only one study to date has evaluated models of college students. Further, no study has evaluated potential shifts in mental models because of taking a course or what specific factors shape these models prior to college. The objectives of this study were to assess environmental models of college students and determine whether a course on âEnvironmental Conservationâ reinforces or influences studentsâ mental models by the end of the course. We compared environmental metal models at the start and end of our course using the Environments Task tool. Students were asked to provide pictorial and written descriptions of their mental models at both time periods. Additionally, photographs were used to explore student beliefs on environmental representations and questions were used to assess sources of prior environmental knowledge of students at the start of the semester. Results show that pictorial and written mental models differed from one another at the beginning as well as the end of the semester. More students identified humans as a part of the environment in their pictures by the end of the semester compared to the beginning, but no such shifts were noted in the written description. Students identified secondary school courses, life experiences such as growing up on a farm or ranch or hunting and fishing, and their family members as their primary sources of environmental information prior to taking the course. In total, these results indicate that mental models remain underdeveloped after this specific 16-week course and that these models may be more fixed by earlier educational experiences than previously believed. Recommendations for future environmental education are also provided
S-NPP ATMS Instrument Prelaunch and On-Orbit Performance Evaluation
The first of a new generation of microwave sounders was launched aboard the Suomi-National Polar-Orbiting Partnership satellite in October 2011. The Advanced Technology Microwave Sounder (ATMS) combines the capabilities and channel sets of three predecessor sounders into a single package to provide information on the atmospheric vertical temperature and moisture profiles that are the most critical observations needed for numerical weather forecast models. Enhancements include size/mass/power approximately one third of the previous total, three new sounding channels, the first space-based, Nyquist-sampled cross-track microwave temperature soundings for improved fusion with infrared soundings, plus improved temperature control and reliability. This paper describes the ATMS characteristics versus its predecessor, the advanced microwave sounding unit (AMSU), and presents the first comprehensive evaluation of key prelaunch and on-orbit performance parameters. Two-year on-orbit performance shows that the ATMS has maintained very stable radiometric sensitivity, in agreement with prelaunch data, meeting requirements for all channels (with margins of ~40% for channels 1-15), and improvements over AMSU-A when processed for equivalent spatial resolution. The radiometric accuracy, determined by analysis from ground test measurements, and using on-orbit instrument temperatures, also shows large margins relative to requirements (specified as <1.0K for channels 1, 2, and 16-22 and <0.75 K for channels 3-15). A thorough evaluation of the performance of ATMS is especially important for this first proto-flight model unit of what will eventually be a series of ATMS sensors providing operational sounding capability for the U.S. and its international partners well into the next decade
Tissue storage affects lipidome profiling in comparison to in vivo microsampling approach
Low-invasive in vivo solid-phase microextraction (SPME) was used to investigate the lipid profiles of muscle tissue of living fish. Briefly, mixed mode SPME fibers were inserted into the muscle for 20âmin extraction, and then the fibers were desorbed in an optimal mixture of solvents. The obtained lipid profile was then compared and contrasted to that obtained with employment of ex vivo SPME and solid-liquid extraction (SLE) from fish muscle tissue belonging to the same group of fish, following a one-year storage period. Ex vivo SPME analysis of stored muscle samples revealed 10-fold decrease in the number of detected molecular features in comparison to in vivo study. Moreover, in vivo microsampling enabled the identification of different classes of bioactive lipids, including fatty acyls, not present in the lipid profile obtained through ex vivo SPME and SLE, suggesting the alterations occurring in the unbound lipid fraction of the system under study during the storage and also indicating the advantage of the in vivo extraction approach.This work was supported by Environment Canada through the Environmental Damages Fund (Grant EC-129114)
In vivo microsampling to capture the elusive exposome
Bessonneau, V., Ings, J., McMaster, M., Smith, R., Bragg, L., Servos, M., & Pawliszyn, J. (2017). In vivo microsampling to capture the elusive exposome. Scientific Reports, 7, 44038. The final and definitive publication is available through Nature publishing Group via: http://dx.doi.org/10.1038/srep44038Loss and/or degradation of small molecules during sampling, sample transportation and storage can adversely impact biological interpretation of metabolomics data. In this study, we performed in vivo sampling using solid-phase microextraction (SPME) in combination with non-targeted liquid chromatography and high-resolution tandem mass spectrometry (LC-MS/MS) to capture the fish tissue exposome using molecular networking analysis, and the results were contrasted with molecular differences obtained with ex vivo SPME sampling. Based on 494 MS/MS spectra comparisons, we demonstrated that in vivo SPME sampling provided better extraction and stabilization of highly reactive molecules, such as 1-oleoyl-sn-glycero-3-phosphocholine and 1-palmitoleoyl-glycero-3-phosphocholine, from fish tissue samples. This sampling approach, that minimizes sample handling and preparation, offers the opportunity to perform longitudinal monitoring of the exposome in biological systems and improve the reliability of exposure-measurement in exposome-wide association studies.Environment Canada, Environmental Damages Fund (Grant EC-129114) provided to Environment Canada through the Joint Oil Sands Monitoring Program
Prevalence and clinical characteristics of serum neuronal cell surface antibodies in first-episode psychosis: a case-control study
Psychosis is a common presenting feature in antibody-mediated encephalitis, for which prompt recognition and treatment usually leads to remission. We aimed to investigate whether people with circumscribed schizophrenia-like illnesses have such antibodiesâespecially antibodies against the N-methyl-D-aspartate receptor (NMDAR)âmore commonly than do healthy controls.
We recruited patients aged 14â35 years presenting to any of 35 mental health services sites across England with first-episode psychosis, less than 6 weeks of treatment with antipsychotic medication, and a score of 4 or more on at least one selected Positive and Negative Syndrome Scale (PANSS) item. Patients and controls provided venous blood samples. We completed standardised symptom rating scales (PANSS, ACE-III, GAF) at baseline, and tested serum samples for antibodies against NMDAR, LGI1, CASPR2, the GABAA receptor, and the AMPA receptor using live cell-based assays. Treating clinicians assessed outcomes of ICD diagnosis and functioning (GAF) at 6 months. We included healthy controls from the general population, recruited as part of another study in Cambridge, UK.
Between Feb 1, 2013, and Aug 31, 2014, we enrolled 228 patients with first-episode psychosis and 105 healthy controls. 20 (9%) of 228 patients had serum antibodies against one or more of the neuronal cell surface antibodies compared with four (4%) of 105 controls (unadjusted odds ratio 2·4, 95% CI 0·8â7·3). These associations remained non-significant when adjusted for current cigarette smoking, alcohol consumption, and illicit drug use. Seven (3%) patients had NMDAR antibodies compared with no controls (p=0·0204). The other antibodies did not differ between groups. Antibody-positive patients had lower PANSS positive, PANSS total, and catatonia scores than did antibody-negative patients. Patients had comparable scores on other PANSS items, ACE-III, and GAF at baseline, with no difference in outcomes at 6 months.
Some patients with first-episode psychosis had antibodies against NMDAR that might be relevant to their illness, but did not differ from patients without NMDAR antibodies in clinical characteristics. Our study suggests that the only way to detect patients with these potentially pathogenic antibodies is to screen all patients with first-episode psychosis at first presentation.Medical Research Counci
Radiometer Calibration Using Colocated GPS Radio Occultation Measurements
We present a new high-fidelity method of calibrating a cross-track scanning microwave radiometer using Global Positioning System (GPS) radio occultation (GPSRO) measurements. The radiometer and GPSRO receiver periodically observe the same volume of atmosphere near the Earth's limb, and these overlapping measurements are used to calibrate the radiometer. Performance analyses show that absolute calibration accuracy better than 0.25 K is achievable for temperature sounding channels in the 50-60-GHz band for a total-power radiometer using a weakly coupled noise diode for frequent calibration and proximal GPSRO measurements for infrequent (approximately daily) calibration. The method requires GPSRO penetration depth only down to the stratosphere, thus permitting the use of a relatively small GPS antenna. Furthermore, only coarse spacecraft angular knowledge (approximately one degree rms) is required for the technique, as more precise angular knowledge can be retrieved directly from the combined radiometer and GPSRO data, assuming that the radiometer angular sampling is uniform. These features make the technique particularly well suited for implementation on a low-cost CubeSat hosting both radiometer and GPSRO receiver systems on the same spacecraft. We describe a validation platform for this calibration method, the Microwave Radiometer Technology Acceleration (MiRaTA) CubeSat, currently in development for the National Aeronautics and Space Administration (NASA) Earth Science Technology Office. MiRaTA will fly a multiband radiometer and the Compact TEC/Atmosphere GPS Sensor in 2015.United States. Dept. of Defense. Assistant Secretary of Defense for Research & Engineering (United States. Air Force Contract FA8721-05-C-0002
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