137 research outputs found

    Interview with Pat and Sandy Crowe

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    Pat and Sandy Crowe talk about the Woodward Opera Househttps://digital.kenyon.edu/ps_interviews/1024/thumbnail.jp

    Cross-sectional analysis of adverse outcomes in 1,029 pregnancies of Afro-Caribbean women in Trinidad with and without systemic lupus erythematosus

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    The objective of the study was to examine pregnancy outcomes in women with systemic lupus erythematosus (SLE) and population controls in Trinidad. We performed a cross-sectional analysis of adverse outcomes in pregnancies of Afro-Caribbean women with SLE and without SLE. One hundred and twenty-two female adult cases of SLE and 203 neighbourhood age-matched women without SLE were interviewed concerning details of their reproductive history, and the anticardiolipin antibody (ACL) status was established for women with SLE. A total of 1,029 pregnancies were reported (356 by women with SLE, 673 by women without SLE). In women with ≥ 1 pregnancy the total number of pregnancies was similar in women with a diagnosis of SLE and women without; however, a lower proportion of women with SLE had ever been pregnant compared with women without SLE (80% versus 91%, P = 0.002). In multivariate logistic regression analyses adjusted for maternal age, district of residence, pregnancy order and smoking, SLE pregnancies were more than twice as likely to end in foetal death than non-SLE pregnancies (odds ratio (OR), 2.4; 95% confidence interval (CI), 1.2–4.7). This effect was driven by a large increase in the odds of stillbirth (OR, 8.5; 95% CI, 2.5–28.8). The odds of early miscarriage (OR, 1.4; 95% CI, 0.6–3.1) and of mid-trimester miscarriage (OR, 1.9; 95% CI, 0.4–9.5) were higher, but were not statistically significantly different, in SLE pregnancies than in non-SLE pregnancies. The odds of ectopic pregnancy (OR, 7.5; 95% CI, 0.9–62.5) and of preterm birth (OR, 3.4; 95% CI, 1.2–10.0) were higher in SLE pregnancies conceived after diagnosis than in non-SLE pregnancies. There was no evidence of raised levels of IgG or IgM ACL among the majority (93/97 women, 96%) of SLE cases who reported sporadic mid-trimester miscarriage or stillbirth, although there was evidence of high levels of IgM and IgG ACL among women reporting three or more miscarriages and three consecutive miscarriages, and of raised IgG ACL among those experiencing ectopic pregnancy. In conclusion, we found evidence for a large increase in risk of stillbirth in the pregnancies of Afro-Caribbean Trinidadian women with SLE (not accounted for by high ACL status). There was some evidence of an increased risk of preterm delivery and ectopic pregnancy in pregnancies conceived after a diagnosis of maternal SLE

    Improving the Human Condition: Leadership for Justice-Oriented Service-Learning

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    The Banneker History Project (BHP) reconstructed the history of the Benjamin Banneker School, which operated as a segregated school for African Americans from 1915 to 1951. It was a project in social justice education with community service as its base. Here, the authors provide an insider perspective of group dynamics among core leaders for the BHP. Building relationships, working for social justice, and confronting racism are key themes for the group. Leaders recall moments of discomfort, particularly related to issues of race and racism, and describe ways they worked through them. Based on their wisdom of practice, authors offer suggestions for those who might do similar work

    A Longitudinal Study of Pediatricians Early in their Careers: PLACES

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    The American Academy of Pediatrics (AAP) launched the Pediatrician Life and Career Experience Study (PLACES), a longitudinal study that tracks the personal and professional experiences of early career pediatricians, in 2012. We used a multipronged approach to develop the study methodology and survey domains and items, including review of existing literature and qualitative research with the target population. We chose to include 2 cohorts of US pediatricians on the basis of residency graduation dates, including 1 group who were several years out of residency (2002–2004 Residency Graduates Cohort) and a second group who recently graduated from residency at study launch (2009–2011 Residency Graduates Cohort). Recruitment into PLACES was a 2-stage process: (1) random sample recruitment from the target population and completion of an initial intake survey and (2) completion of the first Annual Survey by pediatricians who responded positively to stage 1. Overall, 41.2% of pediatricians randomly selected to participate in PLACES indicated positive interest in the study by completing intake surveys; of this group, 1804 (93.7%) completed the first Annual Survey and were considered enrolled in PLACES. Participants were more likely to be female, AAP members, and graduates of US medical schools compared with the target sample; weights were calculated to adjust for these differences. We will survey PLACES pediatricians 2 times per year. PLACES data will allow the AAP to examine career and life choices and transitions experienced by early-career pediatricians

    Portfolio Vol. V N 1

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    Dippery, Franklin M. Unnamed. Prose. 2. Shields, Margaret. The Dance . Prose. 4. Raymond, Toby. Tundra . Prose. 7. Pruyn, Scott. Lest We Forget . Poem. 9. Tolan, Maurice. Pronounced \u27Mejico\u27 . Picture. 10. Phillips, Alison. Pronounced Mejico . Prose. 10. Benson, Virginia. Matter of Opinion . Poem. 12. Benson, Virginia. Cloud Shadows . Poem. 12. Benson, Virginia. Autumn Organist . Poem. 12. Sherman, Hoyt Leon. Orchard . Picture. 12. Nussbaum, Ervin. The End of John Brown . Picture. 13. Brannon, Pat. Revolution . Poem. 13. Anonymous, Pat. A Dream . Poem. 13. Anonymous, Pat. Her . Poem. 13. Seagrave, Leslie. Tibetan Rug . Prose. 14. Benson, Virginia. Cronin-The Keys of the Kingdom . Prose. 15. Benson, Virginia. Koestler-Darkness at Noon . Prose. 15. Jones, Charles. Mr. Doakes Almost Goes to Washington . Prose. 16. Collins, Peggy. Thespiana . Prose. 18. Smith, Duke. Keeping the Records Straight . Prose. 19

    Association of RGS2 and RGS5 variants with schizophrenia symptom severity

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    Several lines of evidence indicate that Regulator of G Protein Signaling 4 (RGS4) contributes to schizophrenia vulnerability. RGS4 is one of a family of molecules that modulate signaling via G-protein coupled receptors. Five genes encoding members of this family (RGS2, RGS4, RGS5, RGS8 and RGS16) map to chromosome 1q23.3-1q31. Due to overlapping cellular functions and chromosomal proximity, we hypothesized that multiple RGS genes may contribute to schizophrenia severity and treatment responsiveness

    The Ursinus Weekly, May 11, 1964

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    New Lost City Ramblers to perform Friday: Agency sponsors blue grass group • Bombers bombed by MSGA, faculty reviewing • UC scholar wins St. Andrews scholarship • Survey supports APO projects • Loved you Conrad : Spring festival succeeds with new program • Bible fellowship • Two classes elect officers today • Pi Nu Epsilon inducts members • Ursinus Circle • Obituary • Editorial: Attention administration • Mr. Pennypacker stages a remarkable performance: Robbins, Sinclair, Auchincloss and Matusow star in production • Spring hits UC campus with sun, fun and studies • Next President: Johnson • Letter to the Editor • Ursinus thinclads retain MAC crown: Cooper wins two, Dunn ties 440 record; Gladstone, Robart, Walter, relay take 1st • Softballers win; Season undefeated • Batsmen even for week: Defeated Drexel, split with Haverford and lost to LaSalle • Tennis loses 3rd; Bryn Mawr takes 4 • Lacrosse wins 4th; Swamp E-burg 13-3 • MAC summary • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/3110/thumbnail.jp
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