416 research outputs found
Early Localization of Bronchogenic Carcinoma
The performance of a fluorescence imaging device was compared with conventional white-light bronchoscopy in 100 patients with lung cancer, 46 patients with resected stage I non-small cell lung cancer,
10 patients with head and neck cancer, and 67 volunteers who had smoked at least 1 pack of
cigarettes per day for 25 years or more. Using differences in tissue autofluorescence between premalignant,
malignant, and normal tissues, fluorescence bronchoscopy was found to detect significantly
more areas with moderate/severe dysplasia or carcinoma in situ than conventional white-light
bronchoscopy with a similar specificity. Multiple foci of dysplasia or cancer were found in 13–24%
of these individuals. Fluorescence bronchoscopy may be an important adjunct to conventional bronchoscopic
examination to improve our ability to detect and localize premalignant and early lung cancer
lesions
Optimization of Electronic Transport at the Nanoscale through the Formation of Molecular Junctions within Composite Electrodes for Li-battery
National audienc
PILOT: a balloon-borne experiment to measure the polarized FIR emission of dust grains in the interstellar medium
Future cosmology space missions will concentrate on measuring the
polarization of the Cosmic Microwave Background, which potentially carries
invaluable information about the earliest phases of the evolution of our
universe. Such ambitious projects will ultimately be limited by the sensitivity
of the instrument and by the accuracy at which polarized foreground emission
from our own Galaxy can be subtracted out. We present the PILOT balloon project
which will aim at characterizing one of these foreground sources, the
polarization of the dust continuum emission in the diffuse interstellar medium.
The PILOT experiment will also constitute a test-bed for using multiplexed
bolometer arrays for polarization measurements. We present the results of
ground tests obtained just before the first flight of the instrument.Comment: 17 pages, 13 figures. Presented at SPIE, Millimeter, Submillimeter,
and Far-Infrared Detectors and Instrumentation for Astronomy VII. To be
published in Proc. SPIE volume 915
Calibration and First light of the Diabolo photometer at the Millimetre and Infrared Testa Grigia Observatory
We have designed and built a large-throughput dual channel photometer,
Diabolo. This photometer is dedicated to the observation of millimetre
continuum diffuse sources, and in particular, of the Sunyaev-Zel'dovich effect
and of anisotropies of the 3K background. We describe the optical layout and
filtering system of the instrument, which uses two bolometric detectors for
simultaneous observations in two frequency channels at 1.2 and 2.1 mm. The
bolometers are cooled to a working temperature of 0.1 K provided by a compact
dilution cryostat. The photometric and angular responses of the instrument are
measured in the laboratory. First astronomical light was detected in March 1995
at the focus of the new Millimetre and Infrared Testa Grigia Observatory (MITO)
Telescope. The established sensitivity of the system is of 7 mK_RJ s^1/2$. For
a typical map of at least 10 beams, with one hour of integration per beam, one
can achieve the rms values of y_SZ ~ 7 10^-5 and the 3K background anisotropy
Delta T/T ~ 7 10^-5, in winter conditions. We also report on a novel bolometer
AC readout circuit which allows for the first time total power measurements on
the sky. This technique alleviates (but does not forbid) the use of chopping
with a secondary mirror. This technique and the dilution fridge concept will be
used in future scan--modulated space instrument like the ESA Planck mission
project.Comment: 10 pages, LaTeX, 12 figures, accepted for publication in Astronomy
and Astrophysics Supplement Serie
3,4-Phenylenedioxythiophene (PheDOT): a novel platform for the synthesis of planar substituted pi-donor conjugated systems
3,4-Phenylenedioxythiophene (PheDOT), a benzenic analogue of 3,4-ethylenedioxythiophene (EDOT), has been synthesized using two different routes namely etherification of 2,5-dicarboethoxy-3,4-dihydroxythiophene with halo-aromatics and transetherification of 3,4-dimethoxythiophene with catechols. Quantum calculations and electrochemical measurements show that replacement of the ethylene bridge of EDOT by a phenyl group leads to an increase of the HOMO level and to a stabilization of the cation radical, making electropolymerization of PheDOT more difficult than that of EDOT. The synthesis of several PheDOT derivatives is described together with preliminary results on their electrochemical polymerization and on the properties of the resulting polymers and copolymers
Sharks of the order Carcharhiniformes from the British Coniacian, Santonian and Campanian (Upper Cretaceous).
Bulk sampling of phosphate-rich horizons within the British Coniacian to Campanian (Upper Cretaceous) yielded very large samples of shark and ray teeth. All of these samples yielded teeth of diverse members of the Carcharhiniformes, which commonly dominate the fauna. The following species are recorded and described: Pseudoscyliorhinus reussi (Herman, 1977) comb. nov., Crassescyliorhinus germanicus (Herman, 1982) gen. nov., Scyliorhinus elongatus (Davis, 1887), Scyliorhinus brumarivulensis sp. nov., ? Palaeoscyllium sp., Prohaploblepharus riegrafi (Müller, 1989) gen. nov., ? Cretascyliorhinus sp., Scyliorhinidae inc. sedis 1, Scyliorhinidae inc. sedis 2, Pteroscyllium hermani sp. nov., Protoscyliorhinus sp., Leptocharias cretaceus sp. nov., Palaeogaleus havreensis Herman, 1977, Paratriakis subserratus sp. nov., Paratriakis tenuis sp. nov., Paratriakis sp. indet. and ? Loxodon sp. Taxa belonging to the families ?Proscylliidae, Leptochariidae, and Carcharhinidae are described from the Cretaceous for the first time. The evolutionary and palaeoecological implications of these newly recognised faunas are discussed
Suppression of Phase Separation in LiFePO4 Nanoparticles During Battery Discharge
Using a novel electrochemical phase-field model, we question the common
belief that LixFePO4 nanoparticles separate into Li-rich and Li-poor phases
during battery discharge. For small currents, spinodal decomposition or
nucleation leads to moving phase boundaries. Above a critical current density
(in the Tafel regime), the spinodal disappears, and particles fill
homogeneously, which may explain the superior rate capability and long cycle
life of nano-LiFePO4 cathodes.Comment: 27 pages, 8 figure
Design and tests of high sensitivity NTD Ge thermometers for the Planck-High Frequency Instrument
The High Frequency Instrument of Planck needs high sensitivity semi-conductors at low temperature to monitor the temperature of the bolometer plate. We have modeled such thermometers by using a semi-analytical approach of Anderson insulators, taking into account both the electrical field and the electron/phonon decoupling effects. The optimized design uses convenient NTD Ge material and has larger dimension than the initial design. The first measurements of these optimized thermometers showed a significant thermal de-coupling effect due to Kapitza resistance with its mechanical support. Nevertheless, a sensitivity of about 8 nK.Hz^(–0.5), not far from the predicted one, was obtained. The noise spectrum of the thermometer was flat down to 1 Hz, dominated at lower frequency by the thermal fluctuations
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