Scaling Invariance in a Time-Dependent Elliptical Billiard

We study some dynamical properties of a classical time-dependent elliptical billiard. We consider periodically moving boundary and collisions between the particle and the boundary are assumed to be elastic. Our results confirm that although the static elliptical billiard is an integrable system, after to introduce time-dependent perturbation on the boundary the unlimited energy growth is observed. The behaviour of the average velocity is described using scaling arguments

Predicted defect induced vortex core switching in thin magnetic nanodisks

We investigate the influence of artificial defects (small holes) inserted into magnetic nanodisks on the vortex core dynamics. One and two holes (antidots) are considered. In general, the core falls into the hole but, in particular, we would like to remark an interesting phenomenon not yet observed, which is the vortex core switching induced by the vortex-hole interactions. It occurs for the case with only one hole and for very special conditions involving the hole size and position as well as the disk size. Any small deformation in the disk geometry such as the presence of a second antidot changes completely the vortex dynamics and the vortex core eventually falls into one of the defects. After trapped, the vortex center still oscillates with a very high frequency and small amplitude around the defect center.Comment: 11pages, Revtex format, 17 figure

Composição do amido de diferentes clones de mandioca.

Introdução: O amido é a principal reserva de carboidratos nas plantas, sendo o componente mais abundante na raiz de mandioca (Manihot esculenta Crantz). Trata-se de um biopolímero composto de glicose, possuindo duas estruturas diferentes, a amilose e a amilopectina. A proporção de amilose e amilopectina é de 1:3 para a maioria dos amidos, mas pode variar em função da fonte botânica e variedade de uma mesma espécie. As propriedades físico-químicas do amido variam com a razão amilose/amilopectina, grau de ramificação da amilose e da amilopectina e tamanho dos grânulos. Por isso, a caracterização do amido extraído de clones de mandioca colhidos em épocas distintas pode possibilitar avanços significativos para o setor agroindustrial da mandioca visando atender às exigências do mercado consumidor. [...]

Biological Function and Molecular Mapping of M Antigen in Yeast Phase of Histoplasma capsulatum

Histoplasmosis, due to the intracellular fungus Histoplasma capsulatum, can be diagnosed by demonstrating the presence of antibodies specific to the immunodominant M antigen. However, the role of this protein in the pathogenesis of histoplasmosis has not been elucidated. We sought to structurally and immunologically characterize the protein, determine yeast cell surface expression, and confirm catalase activity. A 3D-rendering of the M antigen by homology modeling revealed that the structures and domains closely resemble characterized fungal catalases. We generated monoclonal antibodies (mAbs) to the protein and determined that the M antigen is present on the yeast cell surface and in cell wall/cell membrane preparations. Similarly, we found that the majority of catalase activity was in extracts containing fungal surface antigens and that the M antigen is not significantly secreted by live yeast cells. The mAbs also identified unique epitopes on the M antigen. The localization of the M antigen to the cell surface of H. capsulatum yeast and the characterization of the protein's major epitopes have important implications since it demonstrates that although the protein may participate in protecting the fungus against oxidative stress it is also accessible to host immune cells and antibody

Pulmonary Abnormalities in Mice with Paracoccidioidomycosis: A Sequential Study Comparing High Resolution Computed Tomography and Pathologic Findings

Paracoccidioidomycosis (PCM) is a fungal infection caused by the dimorphic fungus Paracoccidioides brasiliensis. It occurs preferentially in rural workers in whom the disease is severe and may cause incapacitating pulmonary sequelae. Assessment of disease progression and treatment outcome normally includes chest x-rays or CT studies. Existing experimental PCM models have focused on several aspects, but none has done a radiologic or image follow-up evaluation of pulmonary lesions considered as the fungus primary target. In this study, the lungs of mice infected with fungal conidia were studied sequentially during the chronic stage of their experimental mycosis by noninvasive high resolution medical computed tomography, and at time of sacrifice, also by histopathology to characterize pulmonary abnormalities. Three basic lung lesion patterns were revealed by both techniques: nodular-diffuse, confluent and pseudo-tumoral which were located mainly around the hilus thus accurately reflecting the situation in human patients. The experimental design of this study decreases the need to sacrifice a large number of animals, and serves to monitor treatment efficacy by means of a more rational approach to the study of human pulmonary diseases. The findings we are reporting open new avenues for experimental research, increase our understanding of the mycosis pathogenesis and consequently have repercussions in patients' care