2 research outputs found

    Estado nutricional y rendimiento acad茅mico en estudiantes de 5 a帽os de edad de una instituci贸n educativa de Independencia-2022

    Get PDF
    El presente trabajo de investigaci贸n tuvo como objetivo general, determinar la relaci贸n que existe entre el estado nutricional y el rendimiento acad茅mico en estudiantes de 5 a帽os de edad de una Instituci贸n Educativa de Independencia- 2022. La cual se utiliz贸 una metodolog铆a con enfoque cuantitativo, de dise帽o correlacional, de tipo b谩sica - no experimental. cont贸 con una poblaci贸n de 190 estudiantes cuya muestra fue 106 estudiantes de 5 a帽os del turno ma帽ana y tarde, as铆 mismo, se aplic贸 la t茅cnica mediante la observaci贸n y el instrumento utilizado fue la gu铆a de observaci贸n . Los instrumentos se dieron por la prueba Rho de Spearman, dicha prueba paso por la validaci贸n de juicio de expertos quienes certificaron su aplicabilidad. La obtenci贸n de resultado llego a la conclusi贸n que existe una correlaci贸n entre ambas variables de estudio, el Rho de Spearman p= 0,811 lo que nos da como significado una relaci贸n moderada entre las variables de estudio, con una significancia de 0,000 (p< 0,05), por lo que se puede deducir que el estado nutricional si se relaciona con el rendimiento acad茅mico en los estudiantes de 5 a帽os de edad de una Instituci贸n educativa de Independencia-2022

    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    No full text
    In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
    corecore