Ministernotomy approach for surgery of the aortic root and ascending aorta

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Static and Dynamic 4-Way Handshake Solutions to Avoid Denial of Service Attack in Wi-Fi Protected Access and IEEE 802.11i

This paper focuses on WPA and IEEE 802.11i protocols that represent two important solutions in the wireless environment. Scenarios where it is possible to produce a DoS attack and DoS flooding attacks are outlined. The last phase of the authentication process, represented by the 4-way handshake procedure, is shown to be unsafe from DoS attack. This can produce the undesired effect of memory exhaustion if a flooding DoS attack is conducted. In order to avoid DoS attack without increasing the complexity of wireless mobile devices too much and without changing through some further control fields of the frame structure of wireless security protocols, a solution is found and an extension of WPA and IEEE 802.11 is proposed. A protocol extension with three "static" variants and with a resource-aware dynamic approach is considered. The three enhancements to the standard protocols are achieved through some simple changes on the client side and they are robust against DoS and DoS flooding attack. Advantages introduced by the proposal are validated by simulation campaigns and simulation parameters such as attempted attacks, successful attacks, and CPU load, while the algorithm execution time is evaluated. Simulation results show how the three static solutions avoid memory exhaustion and present a good performance in terms of CPU load and execution time in comparison with the standard WPA and IEEE 802.11i protocols. However, if the mobile device presents different resource availability in terms of CPU and memory or if resource availability significantly changes in time, a dynamic approach that is able to switch among three different modalities could be more suitable

Congenital musculoskeletal abnormalities associated with aortic, pulmonary and iliac aneurysms

We present the case of a young patient with severe congenital musculoskeletal abnormalities. associated with different pathologies, with involvement of the arterial tree on both the systemic and pulmonary circulation, and involvement of the lungs due to thoracic hypoplasia. The presence of such extensive pathology raises the question of the suitability of such patients to undergo major corrective cardiac surgery procedures. (Cardiol J 2010; 17, 4: 412-414

Superior Vena Cava Syndrome in a Patient with Polycytemia Vera: Diagnosis and Treatment

Polycythemia vera is a myeloproliferative disorder characterized by thrombotic complications both in the arterial and venous systems. We report the case of a 55-year-old patient affected by polycythemia vera, presenting with acute superior vena cava syndrome due to thrombosis of the upper part of the superior vena cava. Diagnosis was done clinically and by computed tomography scan and showed an unusual finding: an air bubble trapped in the brachiocephalic venous trunk. The patient underwent emergency surgery. Diagnosis and treatment of the case are discussed

Geotechnical Characterization of a Soft Clay Soil Subjected to a Preloading Embankment

The paper presents the geotechnical characterization of a clay soil subjected to a preloading embankment for the construction of an industrial electronics building in the industrial area (STM M6) of Catania (Sicily, Italy). To determine the geological profile and the geotechnical characteristics of the soil, the site was well investigated by means of in situ and laboratory tests. The following in situ geotechnical tests were carried out: Borings, SPT, CPT, PLT and dynamic in situ tests have been performed. Among them Down-Hole (D-H), Cross-Hole (C-H), SASW and recently Seismic Dilatometer Marchetti Tests (SDMT) have been carried out, with the aim to evaluate the soil profile of shear waves velocity (Vs). Moreover the following laboratory tests were carried out on undisturbed samples retrieved with a 86 mm diameter Shelby sampler: Oedometer tests, Direct shear tests, Triaxial Tests, Resonant Column and Torsional shear tests. Static and dynamic parameters were compared by in situ and laboratory tests. A significantly correspondence between the values of the geotechnical parameters derived from laboratory and in situ tests was observed. The in situ and laboratory geotechnical analysis gives the parameters to evaluate the performance of soil subjected to soil embankment by mathematical modeling

A Seismic Geotechnical Hazard Study in the Ancient City of Noto (Italy)

Abstract South-Eastern Sicily has been affected in past times by several destroying earthquakes with high values of estimated magnitude. The aim of the seismic hazard microzonation studies performed at the City of Noto is to quantify the spatial variability of the site response on some typical historical scenario earthquakes that would be expected in the area. In order to quantify the expected ground motion, the manner in which the seismic signal is propagating through the subsurface has been defined. Propagation is particularly affected by the local geology and by the geotechnical dynamic ground conditions of the studied area. The data largely consist of the stratigraphic profiles obtained by in situ tests i.e. borings, MASW tests, Down-Hole tests, SDMT tests; some are accompanied by static and dynamic laboratory tests, such as Resonant Column, monotonic compression loading Triaxial tests and Direct shear tests. Processing of all these data allowed the ground response analysis at the surface, in terms of time history and response spectra, of some areas of the city using the linear-equivalent codes EERA, STRATA and DEEPSOIL, useful for microzonation of seismic geotechnical hazards

Septic skin lesions: an uncommon manifestation of peripheral prosthetic vascular graft infection

Peripheral prosthetic vascular graft infection following lower limb surgical revascularization is a relatively rare but serious condition. A case of early infection and occlusion of a above-knee femoro-popliteal artery prosthetic bypass is here reported. It was accompanied by acute lower limb ischemia, fever and distally by embolic septic skin lesions

Self-assembly of silver nanoparticles and bacteriophage

Biohybrid nanostructured materials, composed of both inorganic nanoparticles and biomolecules, offer prospects for many new applications in extremely diverse fields such as chemistry, physics, engineering, medicine and nanobiotechnology. In the recent years, Phage display technique has been extensively used to generate phage clones displaying surface peptides with functionality towards organic materials. Screening and selection of phage displayed material binding peptides has attracted great interest because of their use for development of hybrid materials with multiple functionalities. Here, we present a self-assembly approach for the construction of hybrid nanostructured networks consisting of M13 P9b phage clone, specific for Pseudomonas aeruginosa, selected by Phage display technology, directly assembled with silver nanoparticles (AgNPs), previously prepared by pulsed laser ablation. These networks are characterized by UV–vis optical spectroscopy, scanning/transmission electron microscopies and Raman spectroscopy. We investigated the influence of different ions and medium pH on self-assembly by evaluating different phage suspension buffers. The assembly of these networks is controlled by electrostatic interactions between the phage pVIII major capsid proteins and the AgNPs. The formation of the AgNPs-phage networks was obtained only in two types of tested buffers at a pH value near the isoelectric point of each pVIII proteins displayed on the surface of the clone. This systematic study allowed to optimize the synthesis procedure to assembly AgNPs and bacteriophage. Such networks find application in the biomedical field of advanced biosensing and targeted gene and drug delivery. Keywords: Phage display, Silver nanoparticles, Self-assembly, Hybrid architecture, Raman spectroscop

Distribution of costameric proteins in normal human ventricular and atrial cardiac muscle.

In the mature heart, the intercalated disc and costameres provide the cell-cell and cell-matrix junctions respectively. Intercalated disc is situated at the bipolar ends of the cardiomyocytes and the myofibrils are anchored at this structure. The costameres mediate integration with the extracellular matrix that covers individual cardiomyocytes laterally. Costameres are considered as "proteic machinery" that appears to comprise two protein complexes: the dystrophin-glycoprotein complex (DGC) and the vinculin-talin-integrin system. There are structural differences between atrial and ventricular myocytes, but there have been relatively few studies that have analyzed costameres and focal adhesion function in cardiac cells. Our previous study carried out only on atrial myocytes, demonstrated that the DGC and talin-vinculin-integrin complexes had a costameric distribution that, unlike skeletal muscle, it localized only on the I band. We performed a further immunohistochemical analysis extending also the evaluation to the normal human cardiac muscle fibers obtained from ventricle and interventricular septum, in order to define the distribution and the spatial relationship between the proteins of the two complexes also in the other heart districts. Immunoconfocal microscopy of cardiac tissue revealed the costameric distribution of DGC and of vinculin-talin-integrin system, the association of all tested proteins in intercalated disks, in disagreement with other Authors, and in T-tubule with irregular spokelike extensions penetrating toward the center of the cell. Moreover, our data showed that all tested proteins colocalize between each other