Quantum Walks of SU(2)_k Anyons on a Ladder

We study the effects of braiding interactions on single anyon dynamics using a quantum walk model on a quasi-1-dimensional ladder filled with stationary anyons. The model includes loss of information of the coin and nonlocal fusion degrees of freedom on every second time step, such that the entanglement between the position states and the exponentially growing auxiliary degrees of freedom is lost. The computational complexity of numerical calculations reduces drastically from the fully coherent anyonic quantum walk model, allowing for relatively long simulations for anyons which are spin-1/2 irreps of SU(2)_k Chern-Simons theory. We find that for Abelian anyons, the walk retains the ballistic spreading velocity just like particles with trivial braiding statistics. For non-Abelian anyons, the numerical results indicate that the spreading velocity is linearly dependent on the number of time steps. By approximating the Kraus generators of the time evolution map by circulant matrices, it is shown that the spatial probability distribution for the k=2 walk, corresponding to Ising model anyons, is equal to the classical unbiased random walk distribution.Comment: 12 pages, 4 figure

Punctuated Equilibrium in Software Evolution

The approach based on paradigm of self-organized criticality proposed for experimental investigation and theoretical modelling of software evolution. The dynamics of modifications studied for three free, open source programs Mozilla, Free-BSD and Emacs using the data from version control systems. Scaling laws typical for the self-organization criticality found. The model of software evolution presenting the natural selection principle is proposed. The results of numerical and analytical investigation of the model are presented. They are in a good agreement with the data collected for the real-world software.Comment: 4 pages, LaTeX, 2 Postscript figure

Edge theories in Projected Entangled Pair State models

We study the edge physics of gapped quantum systems in the framework of Projected Entangled Pair State (PEPS) models. We show that the effective low-energy model for any region acts on the entanglement degrees of freedom at the boundary, corresponding to physical excitations located at the edge. This allows us to determine the edge Hamiltonian in the vicinity of PEPS models, and we demonstrate that by choosing the appropriate bulk perturbation, the edge Hamiltonian can exhibit a rich phase diagram and phase transitions. While for models in the trivial phase any Hamiltonian can be realized at the edge, we show that for topological models, the edge Hamiltonian is constrained by the topological order in the bulk which can e.g. protect a ferromagnetic Ising chain at the edge against spontaneous symmetry breaking.Comment: 5 pages, 4 figure

AN ANALYSIS OF CONSUMER PREFERENCES FOR DELAWARE FARMER DIRECT MARKETS

Consumer/Household Economics,

Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression

background: There is an acute need to uncover biomarkers that reflect the molecular pathologies, underpinning prostate cancer progression and poor patient outcome. We have previously demonstrated that in prostate cancer cell lines PDE4D7 is downregulated in advanced cases of the disease. To investigate further the prognostic power of PDE4D7 expression during prostate cancer progression and assess how downregulation of this PDE isoform may affect disease outcome, we have examined PDE4D7 expression in physiologically relevant primary human samples. methods: About 1405 patient samples across 8 publically available qPCR, Affymetrix Exon 1.0 ST arrays and RNA sequencing data sets were screened for PDE4D7 expression. The TMPRSS2-ERG gene rearrangement status of patient samples was determined by transformation of the exon array and RNA seq expression data to robust z-scores followed by the application of a threshold >3 to define a positive TMPRSS2-ERG gene fusion event in a tumour sample. results: We demonstrate that PDE4D7 expression positively correlates with primary tumour development. We also show a positive association with the highly prostate cancer-specific gene rearrangement between TMPRSS2 and the ETS transcription factor family member ERG. In addition, we find that in primary TMPRSS2-ERG-positive tumours PDE4D7 expression is significantly positively correlated with low-grade disease and a reduced likelihood of progression after primary treatment. Conversely, PDE4D7 transcript levels become significantly decreased in castration resistant prostate cancer (CRPC). conclusions: We further characterise and add physiological relevance to PDE4D7 as a novel marker that is associated with the development and progression of prostate tumours. We propose that the assessment of PDE4D7 levels may provide a novel, independent predictor of post-surgical disease progression

Seismic Performance of Slender C-Shaped Walls Subjected to UniI- and Bi-Directional Loading

Reinforced concrete structural walls are common as the primary lateral load resisting system in modern mid- and high-rise buildings constructed in seismic regions, yet few research programs have investigated the seismic performance of modern, slender walls with nonplanar cross-sectional geometries. Three large-scale, C-shaped wall specimens, designed per ACI 318-08, were tested under uni- and bi-directional loading at the University of Illinois at Urbana-Champaign (UIUC). This paper presents experimental results including the cyclic load-deformation response and measured versus nominal flexural/shear strengths as well as a description of damage sequence. Final failure occurs due to a flexure-tension failure of boundary elements where multiple previously buckled bars fracture. From these tests, it is possible to conclude that with respect to uni- versus bi-directionally loading C-shaped walls have similar strong-axis load-deformation response until 0.75% drift as well as effective flexure/shear stiffness; however, there is a notable reduction in strong-axis ductility due to bi-directional loading. When comparing C-shaped walls to planar walls, the C-shaped specimens exhibit a more ductile flexural-tension controlled response where wall flanges contribute significantly to carrying compressive loads. Additionally, wall flanges and boundary elements are noted to be critical to resisting shear demands after the lightly-reinforced wall web has deteriorated

Take Care- Use Antibiotics Responsibly Swine Practitioner Project

The Take Care - Use Antibrotics Responsibly® program is an antimicrobial resistance and use educat1on and awareness program for pork producers. The program is based on principles and guidelines intended to minimize the development of antimicrobial resistance whrle maximizing animal health The program was developed by the National Pork Board, but veterinarians are key in the delivery of the program on farm. Since there are many factors that contribute to the amounts and types of antimicrobrals used on farm it was decided that the best way to measure program effectiveness was through measurement of changes in the attitude and behaviors of program particrpants

The Wild Turkey in South Dakota

This bulletin provides an extensive look at the wild turkey in South Dakota

Contribution of the Staphylococcus aureus Atl AM and GL murein hydrolase activities in cell division, autolysis, and biofilm formation.

The most prominent murein hydrolase of Staphylococcus aureus, AtlA, is a bifunctional enzyme that undergoes proteolytic cleavage to yield two catalytically active proteins, an amidase (AM) and a glucosaminidase (GL). Although the bifunctional nature of AtlA has long been recognized, most studies have focused on the combined functions of this protein in cell wall metabolism and biofilm development. In this study, we generated mutant derivatives of the clinical S. aureus isolate, UAMS-1, in which one or both of the AM and GL domains of AtlA have been deleted. Examination of these strains revealed that each mutant exhibited growth rates comparable to the parental strain, but showed clumping phenotypes and lysis profiles that were distinct from the parental strain and each other, suggesting distinct roles in cell wall metabolism. Given the known function of autolysis in the release of genomic DNA for use as a biofilm matrix molecule, we also tested the mutants in biofilm assays and found both AM and GL necessary for biofilm development. Furthermore, the use of enzymatically inactive point mutations revealed that both AM and GL must be catalytically active for S. aureus to form a biofilm. The results of this study provide insight into the relative contributions of AM and GL in S. aureus and demonstrate the contribution of Atl-mediated lysis in biofilm development