28 research outputs found

    Totalitaryzm i dusza ludzka

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    Daniela Gromska (1889-1973)

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    O anty-antykomunizmie

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    Ronald Reagan a wyzwania epoki

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    Z wprowadzenia: "Śmierć Ronalda Reagana w czerwcu 2004 r. zamknęła znaczącą epokę w dziejach Europy i świata. Reagan symbolizował pokolenie polityków, którym przyszło działać w czasach szybkiej dekompozycji dwóch, wydawałoby się niepodważalnych pewników politycznych dominujących po drugiej wojnie światowej w świecie zachodnim. Z polityków tych był tym, który przyczynił się w olbrzymiej mierze do podważenia obu z nich."(...

    Inhibitors of sodium-glucose transport protein 2: A new multidirectional therapeutic option for heart failure patients

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    Several mechanisms have been suggested to explain positive cardiovascular effects observed in studies with sodium-glucose co-transporter 2 (SGLT2) inhibitors. The reduction in glucose reabsorption in proximal tubuli induced by SGLT2 inhibitors increases urinary glucose and sodium excretion resulting in increased osmotic diuresis and consequently in decreased plasma volume, followed by reduced preload. In addition, the hemodynamic effects of SGLT2 inhibition were observed in both hyper and euglycemic patients. Due to the complex and multidirectional effects induced by SGLT2 inhibitors, this originally antidiabetic group of drugs has been successfully used to treat patients with heart failure as well as for subjects with chronic kidney disease. Moreover, their therapeutic potential seems to be even broader than the indications studied to date

    Democracy and the republic

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    About the tyranny of freedom

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