Degradable Copolymer Nanoparticles from Radical Ring-Opening Copolymerization between Cyclic Ketene Acetals and Vinyl Ethers

International audienc

Copolymérisation statistique du styrène et de l'acide acrylique contrôlée par le nitroxyde SG1 (application comme stabilisant en milieu aqueux dispersé)

PARIS-BIUSJ-Thèses (751052125) / SudocPARIS-BIUSJ-Physique recherche (751052113) / SudocSudocFranceF

Alain Deloche et Catherine Malabou : la coeur et le cerveay à l'ouvrage

TV interview on artificial intelligence and the book "Metamorphoses of intelligence

Radical Ring-Opening Polymerization: Scope, Limitations, and Application to (Bio)Degradable Materials

International audienceCyclic monomers bearing either vinyl or exomethylene groups have the ability to be polymerized through a radical pathway via a ring-opening mechanism (addition fragmentation process), leading to the introduction of functionalities in the polymer backbone. Radical ring-opening polymerization (rROP) combines the advantages of both ring-opening polymerization and radical polymerization, that is the preparation of polymers bearing heteroatoms in the backbone but with the ease and robustness of a radical process. This current review presents a comprehensive description of rROP by detailing: (0 the various monomers that polymerize through rROP; (ii) the main parameters that govern the rROP mechanism; (iii) the copolymerization by conventional or controlled/living radical polymerization between rROP monomers and traditional vinyl monomers to obtain copolymers with advanced properties; (iv) the different applications (low shrinkage materials and pieparation of (bio)degradable materials) of rROP monomer-containing materials, and (v) the main alternatives to rROP to induce degradability to materials obtained by a radical polymerization

Simultaneous reversible addition fragmentation chain transfer and ring-opening polymerization

The simultaneous ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) and 2-hydroxyethyl methacrylate (HEMA) polymerization via reversible addition fragmentation chain transfer (RAFT) chemistry and the possible access to graft copolymers with degradable and nondegradable segments is investigated. HEMA and ε-CL are reacted in the presence of cyanoisopropyl dithiobenzoate (CPDB) and tin(II) 2-ethylhexanoate (Sn(Oct)2) under typical ROP conditions (T > 100°C) using toluene as the solvent in order to lead to the graft copolymer PHEMA-g-PCL. Graft copolymer formation is evidenced by a combination of size-exclusion chromatography (SEC) and NMR analyses as well as confirmed by the hydrolysis of the PCL segments of the copolymer. With targeted copolymers containing at least 10% weight of PHEMA and relatively small PHEMA backbones (ca. 5,000-10,000 g mol-1) the copolymer grafting density is higher than 90%. The ratio of free HEMA-PCL homopolymer produced during the "one-step" process was found to depend on the HEMA concentration, as well as the half-life time of the radical initiator used. © 2008 Wiley Periodicals, Inc

Intermolecular radical 1,2-addition of the BlocBuilder MA alkoxyamine onto activated olefins: a versatile tool for the synthesis of complex macromolecular architecture

International audienceThis review described the potential of the intermolecular radical 1,2-addition from the commercially available BlocBuilder MA alkoxyamine onto activated olefins to synthesize either new functionalized alkoxyamines or various macromolecular architectures. Following this approach, diblock, triblock copolymers, star polymers and hybrid materials are then easily prepared. The various applications of such architectures will be briefly reviewed. Interestingly this new synthetic tool widely expands the range of complex macromolecular architectures which could be obtained by the nitroxide-mediated polymerization (NMP) process

Polyesters by a Radical Pathway: Rationalization of the Cyclic Ketene Acetal Efficiency

International audienc

Polyesters by a Radical Pathway: Rationalization of the Cyclic Ketene Acetal Efficiency

International audienc