584 research outputs found
SIGHT - A Tool for Building Multi-Media Structured-Document Interactive Editing and Formatting Applications
SIGHT is a tool for building applications that edit and format multi-media structured documents. The media supported include text, line graphics, handwriting, images and audio. These information media are maintained in a single integrated hierarchical database. The document architecture models documents as trees in which nodes can be shared, i.e., as directed acyclic graphs. For each document there is a logical (or abstract) represention tree and one or more physical (or layout) representation trees. A physical representation is the result of applying the formatter to a logical representation. Both trees are separate but share document content data. The physical representation is displayable and printable, but all editing effectively occurs in the logical representation. Any number of document types can be supported. A document type is defined by the node types it can contain, by how these node types can be hierarchically organized, by what each node type can contain and by the format specifications used in formatting the document. SIGHT provides applications a language to define new document types, a Core Editor, various specialized editors and a formatter. The Core Editor is further subdivided into a generic Tree Editor and a generic Node Editor. Both are not limited by document types but are sensitive to them. The Core Editor is the primary editing system
A Study of Cathodoluminescence and Trace Element Compositional Zoning in Natural Quartz from Volcanic Rocks: Mapping Titanium Content in Quartz
Observatory's linguistic landscape: semiotic appropriation and the reinvention of space
Using a longitudinal ethnographic study of the linguistic landscape (LL) in
Observatory's business corridor of Lower Main Road, the paper explores changes
brought about by the influx of immigrant Africans, their artefacts and language
practices. The paper uses the changes in the LL over time and the development of an
"African Corner" within Lower Main Road, to illustrate the appropriation of space and
the unpredictability, which comes along with highly mobile, technological and
multicultural citizens. It is argued that changes in the LL are part of the act of claiming
and appropriating space wherein space becomes summarily recontexualized and hence
reinvented and "owned" by new actors. It is also argued that space ownership can be
concealed through what we have called "brand anonymity" strategies in which the
identity of the owner is deliberately concealed behind global brands. We conclude that
space is pliable and mobile, and that, it is the people within space who carve out new
social practices in their appropriated space.IBS
Dynamic Impedance of Two-Dimensional Superconducting Films Near the Superconducting Transition
The sheet impedances, Z(w,T), of several superconducting a-Mo77Ge23 films and
one In/InOx film have been measured in zero field using a two-coil mutual
inductance technique at frequencies from 100 Hz to 100 kHz. Z(w,T) is found to
have three contributions: the inductive superfluid, renormalized by nonvortex
phase fluctuations; conventional vortex-antivortex pairs, whose contribution
turns on very rapidly just below the usual Kosterlitz-Thouless-Berezinskii
unbinding temperature; and an anomalous contribution. The latter is
predominantly resistive, persists well below the KTB temperature, and is weakly
dependent on frequency down to remarkably low frequencies, at least 100 Hz. It
increases with T as e-U'(T)/kT, where the activation energy, U'(T), is about
half the energy to create a vortex-antivortex pair, indicating that the
frequency dependence is that of individual excitations, rather than critical
behavior.Comment: 10 pages, 10 figs; subm PR
Critical Exponents of the Fully Frustrated 2-D Xy Model
We present a detailed study of the critical properties of the 2-D XY model
with maximal frustration in a square lattice. We use extensive Monte Carlo
simulations to study the thermodynamics of the spin and chiral degrees of
freedom, concentrating on their correlation functions. The gauge invariant
spin-spin correlation functions are calculated close to the critical point for
lattice sizes up to ; the chiral correlation functions are
studied on lattices up to . We find that the critical exponents of
the spin phase transition are , and , which are to be
compared with the unfrustrated XY model exponents and . We
also find that the critical exponents of the chiral transition are
, , , and
, which are different from the expected 2-D Ising
critical exponents. The spin-phase transition occurs at which
is about 7\% above the estimated chiral critical temperature . However, because of the size of the statistical errors, it is
difficult to decide with certainty whether the transitions occur at the same or
at slightly different temperatures. Finally, the jump in the helicity modulus
in the fully frustrated system is found to be about 23\% below the unfrustrated
universal value. The most important consequence of these results is that the
fully frustrated XY model appears to be in a novel universality class. Recent
successful comparisons of some of these results with experimental data are also
briefly discussed. (TO APPEAR IN PRB)Comment: 47 pages (PHYZZX
Impact of the Cancer Prevention and Control Research Network: Accelerating the Translation of Research Into Practice
The Cancer Prevention and Control Research Network (CPCRN) is a thematic network dedicated to accelerating the adoption of evidence-based cancer prevention and control practices in communities by advancing dissemination and implementation science. Funded by the Centers for Disease Control and Prevention and National Cancer Institute, CPCRN has operated at two levels: Each participating Network Center conducts research projects with primarily local partners as well as multicenter collaborative research projects with state and national partners. Through multicenter collaboration, thematic networks leverage the expertise, resources, and partnerships of participating centers to conduct research projects collectively that might not be feasible individually. Although multicenter collaboration often is advocated, it is challenging to promote and assess. Using bibliometric network analysis and other graphical methods, this paper describes CPCRN’s multicenter publication progression from 2004 to 2014. Searching PubMed, Scopus, and Web of Science in 2014 identified 249 peer-reviewed CPCRN publications involving two or more centers out of 6,534 total. The research and public health impact of these multicenter collaborative projects initiated by CPCRN during that 10-year period were then examined. CPCRN established numerous workgroups around topics such as: 2-1-1, training and technical assistance, colorectal cancer control, federally qualified health centers, cancer survivorship, and human papillomavirus. The paper discusses the challenges that arise in promoting multicenter collaboration and the strategies that CPCRN uses to address those challenges. The lessons learned should broadly interest those seeking to promote multisite collaboration to address public health problems, such as cancer prevention and control
Study on COgnition and Prognosis in the Elderly (SCOPE)
Blood Press. 1999;8(3):177-83.
Study on COgnition and Prognosis in the Elderly (SCOPE).
Hansson L, Lithell H, Skoog I, Baro F, Bánki CM, Breteler M, Carbonin PU, Castaigne A, Correia M, Degaute JP, Elmfeldt D, Engedal K, Farsang C, Ferro J, Hachinski V, Hofman A, James OF, Krisin E, Leeman M, de Leeuw PW, Leys D, Lobo A, Nordby G, Olofsson B, Zanchetti A, et al.
University of Uppsala, Department of Public Health, Sweden.
Abstract
The Study on COgnition and Prognosis in the Elderly (SCOPE) is a multicentre, prospective, randomized, double-blind, parallel-group study designed to compare the effects of candesartan cilexetil and placebo in elderly patients with mild hypertension. The primary objective of the study is to assess the effect of candesartan cilexetil on major cardiovascular events. The secondary objectives of the study are to assess the effect of candesartan cilexetil on cognitive function and on total mortality, cardiovascular mortality, myocardial infarction, stroke, renal function, hospitalization, quality of life and health economics. Male and female patients aged between 70 and 89 years, with a sitting systolic blood pressure (SBP) of 160-179 mmHg and/or diastolic blood pressure (DBP) of 90-99 mmHg, and a Mini-Mental State Examination (MMSE) score of 24 or above, are eligible for the study. The overall target study population is 4000 patients, at least 1000 of whom are also to be assessed for quality of life and health economics data. After an open run-in period lasting 1-3 months, during which patients are assessed for eligibility and those who are already on antihypertensive therapy at enrolment are switched to hydrochlorothiazide 12.5 mg o.d., patients are randomized to receive either candesartan cilexetil 8 mg once daily (o.d.) or matching placebo o.d. At subsequent study visits, if SBP remains >160 mmHg, or has decreased by 85 mmHg, study treatment is doubled to candesartan cilexetil 16 mg o.d. or two placebo tablets o.d. Recruitment was completed in January 1999. At that time 4964 patients had been randomized. All randomized patients will be followed for an additional 2 years. If the event rate is lower than anticipated, the follow-up will be prolonged.
PMID: 10595696 [PubMed - indexed for MEDLINE
Quantum Interference in Superconducting Wire Networks and Josephson Junction Arrays: Analytical Approach based on Multiple-Loop Aharonov-Bohm Feynman Path-Integrals
We investigate analytically and numerically the mean-field
superconducting-normal phase boundaries of two-dimensional superconducting wire
networks and Josephson junction arrays immersed in a transverse magnetic field.
The geometries we consider include square, honeycomb, triangular, and kagome'
lattices. Our approach is based on an analytical study of multiple-loop
Aharonov-Bohm effects: the quantum interference between different electron
closed paths where each one of them encloses a net magnetic flux. Specifically,
we compute exactly the sums of magnetic phase factors, i.e., the lattice path
integrals, on all closed lattice paths of different lengths. A very large
number, e.g., up to for the square lattice, exact lattice path
integrals are obtained. Analytic results of these lattice path integrals then
enable us to obtain the resistive transition temperature as a continuous
function of the field. In particular, we can analyze measurable effects on the
superconducting transition temperature, , as a function of the magnetic
filed , originating from electron trajectories over loops of various
lengths. In addition to systematically deriving previously observed features,
and understanding the physical origin of the dips in as a result of
multiple-loop quantum interference effects, we also find novel results. In
particular, we explicitly derive the self-similarity in the phase diagram of
square networks. Our approach allows us to analyze the complex structure
present in the phase boundaries from the viewpoint of quantum interference
effects due to the electron motion on the underlying lattices.Comment: 18 PRB-type pages, plus 8 large figure
Study on COgnition and Prognosis in the Elderly (SCOPE): baseline characteristics
Blood Press. 2000;9(2-3):146-51.
Study on COgnition and Prognosis in the Elderly (SCOPE): baseline characteristics.
Hansson L, Lithell H, Skoog I, Baro F, Bánki CM, Breteler M, Castaigne A, Correia M, Degaute JP, Elmfeldt D, Engedal K, Farsang C, Ferro J, Hachinski V, Hofman A, James OF, Krisin E, Leeman M, de Leeuw PW, Leys D, Lobo A, Nordby G, Olofsson B, Opolski G, Prince M, Reischies FM.
University of Uppsala, Department of Public Health, Clinical Hypertension Research, Sweden.
Abstract
The Study on COgnition and Prognosis in the Elderly (SCOPE) is a multi-centre, prospective, randomized, double-blind, parallel-group study. The primary objective of SCOPE is to assess the effect of the angiotensin II type 1 (AT1) receptor blocker, candesartan cilexetil 8-16 mg once daily, on major cardiovascular events in elderly patients (70-89 years of age) with mild hypertension (DBP 90-99 and/or SBP 160-179 mmHg). The secondary objectives of the study are to test the hypothesis that antihypertensive therapy can prevent cognitive decline (as measured by the Mini Mental State Examination, MMSE) and dementia, and to assess the effect of therapy on total mortality, myocardial infarction (MI), stroke, renal function, and hospitalization. A total of 4964 patients from 15 participating countries were recruited during the randomization phase of SCOPE, exceeding the target population of 4000. The mean age of the patients at enrolment was 76 years, the ratio of male to female patients was approximately 1:2, and 52% of patients were already being treated with an antihypertensive agent at enrolment. The majority of patients (88%) were educated to at least primary school level. At randomization, mean sitting blood pressure values were SBP 166 mmHg and DBP 90 mmHg, and the mean MMSE score was 28. Previous cardiovascular disease in the study population included myocardial infarction (4%), stroke (4%) and atrial fibrillation (4%). Men, more often than women, had a history of previous MI, stroke and atrial fibrillation. A greater percentage of men were smokers (13% vs 6% in women) and had attended university (11% vs 3% of women). Of the randomized patients, 21% were 80 years of age. In this age group smoking was less common (4% vs 10% for 70-79-year-olds) and fewer had attended university (4% vs 7% for 70-79-year-olds). The incidence of MI was similar in both age groups. However, stroke and atrial fibrillation had occurred approximately twice as frequently in the older patients. The patients' mean age at baseline was similar in the participating countries, and most countries showed the approximate 1:2 ratio for male to female patients. There was also little inter-country variation in terms of mean SBP, DBP or MMSE score. However, there was considerable regional variation in the percentage of patients on therapy prior to enrolment.
PMID: 10855739 [PubMed - indexed for MEDLINE
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