Influenza Vaccination and Mortality: Differentiating Vaccine Effects From Bias

It is widely believed that influenza (flu) vaccination of the elderly reduces all-cause mortality, yet randomized trials for assessing vaccine effectiveness are not feasible and the observational research has been controversial. Efforts to differentiate vaccine effectiveness from selection bias have been problematic. The authors examined mortality before, during, and after 9 flu seasons in relation to time-varying vaccination status in an elderly California population in which 115,823 deaths occurred from 1996 to 2005, including 20,484 deaths during laboratory-defined flu seasons. Vaccine coverage averaged 63%; excess mortality when the flu virus was circulating averaged 7.8%. In analyses that omitted weeks when flu circulated, the odds ratio measuring the vaccination-mortality association increased monotonically from 0.34 early in November to 0.56 in January, 0.67 in April, and 0.76 in August. This reflects the trajectory of selection effects in the absence of flu. In analyses that included weeks with flu and adjustment for selection effects, flu season multiplied the odds ratio by 0.954. The corresponding vaccine effectiveness estimate was 4.6% (95% confidence interval: 0.7, 8.3). To differentiate vaccine effects from selection bias, the authors used logistic regression with a novel case-centered specification that may be useful in other population-based studies when the exposure-outcome association varies markedly over time

Extragalactic Magnetic Field and the Highest Energy Cosmic Rays

The strength and spectrum of the extragalactic magnetic field are still unknown. Its measurement would help answer the question of whether galactic fields are purely a primordial relic or were dynamically enhanced from a much smaller cosmological seed field. In this letter, we show that the composition, spectrum, and directional distribution of extragalactic ultrahigh energy cosmic rays with energies above \simeq 10^{18}\ev can probe the large scale component of the extragalactic magnetic field below the present observational upper limit of $10^{-9}$ Gauss. Cosmic ray detectors under construction or currently in the proposal stage should be able to test the existence of the extragalactic magnetic fields on scales of a few to tens of Mpc and strengths in the range $\simeq 10^{-10} - 10^{-9}$ Gauss.Comment: 11 pages with 3 postscript figures; LaTeX with AASTeX macros; uuencoded 3 .eps figures; submitted to the ApJL; a postscript version of the paper also available at http://astro.uchicago.edu/home/web/sjlee/pub.htm

Modeling of Aerosol Vertical Profiles Using GIS and Remote Sensing

The use of Geographic Information Systems (GIS) and Remote Sensing (RS) by climatologists, environmentalists and urban planners for three dimensional modeling and visualization of the landscape is well established. However no previous study has implemented these techniques for 3D modeling of atmospheric aerosols because air quality data is traditionally measured at ground points, or from satellite images, with no vertical dimension. This study presents a prototype for modeling and visualizing aerosol vertical profiles over a 3D urban landscape in Hong Kong. The method uses a newly developed technique for the derivation of aerosol vertical profiles from AERONET sunphotometer measurements and surface visibility data, and links these to a 3D urban model. This permits automated modeling and visualization of aerosol concentrations at different atmospheric levels over the urban landscape in near-real time. Since the GIS platform permits presentation of the aerosol vertical distribution in 3D, it can be related to the built environment of the city. Examples are given of the applications of the model, including diagnosis of the relative contribution of vehicle emissions to pollution levels in the city, based on increased near-surface concentrations around weekday rush-hour times. The ability to model changes in air quality and visibility from ground level to the top of tall buildings is also demonstrated, and this has implications for energy use and environmental policies for the tall mega-cities of the future

[Fe15]: A Frustrated, Centred Tetrakis Hexahedron

The combination of two different FeIII salts in a solvothermal reaction with triethanolamine results in the formation of a high symmetry [FeIII15] cluster whose structure conforms to a centred, tetrakis hexahedron

Modeling the color evolution of luminous red galaxies - improvements with empirical stellar spectra

Predicting the colors of Luminous Red Galaxies (LRGs) in the Sloan Digital Sky Survey (SDSS) has been a long-standing problem. The g,r,i colors of LRGs are inconsistent with stellar population models over the redshift range 0.1<z<0.7. The g-r colors in the models are on average redder than the data while the r-i colors in the models are bluer towards low redshift. Beyond redshift 0.4, the predicted r-i color becomes instead too red, while the predicted g-r agrees with the data. We provide a solution to this problem, through a combination of new astrophysics and a fundamental change to the stellar population modeling. We find that the use of the empirical library of Pickles (1998) instead of theoretical spectra modifies the predicted colors exactly in the way suggested by the data. The reason is a lower flux in the empirical libraries, with respect to the theoretical ones, in the wavelength range 5500-6500 AA. The discrepancy increases with decreasing effective temperature independently of gravity. This result has general implications for a variety of studies from globular clusters to high-redshift galaxies. The astrophysical part of our solution regards the composition of the stellar populations of these massive Luminous Red Galaxies. We find that on top of the previous effect one needs to consider a model in which ~3% of the stellar mass is in old metal-poor stars. Other solutions such as substantial blue Horizontal Branch at high metallicity or young stellar populations can be ruled out by the data. Our new model provides a better fit to the g-r and r-i colors of LRGs and gives new insight into the formation histories of these most massive galaxies. Our model will also improve the k- and evolutionary corrections for LRGs which are critical for fully exploiting present and future galaxy surveys.Comment: Submitted to ApJ Letters. High resolution version available at http://www.maraston.eu/Maraston_etal_2008.pd

Detection and Monitoring of Marine Pollution Using Remote Sensing Technologies

Recently, the marine habitat has been under pollution threat, which impacts many human activities as well as human life. Increasing concerns about pollution levels in the oceans and coastal regions have led to multiple approaches for measuring and mitigating marine pollution, in order to achieve sustainable marine water quality. Satellite remote sensing, covering large and remote areas, is considered useful for detecting and monitoring marine pollution. Recent developments in sensor technologies have transformed remote sensing into an effective means of monitoring marine areas. Different remote sensing platforms and sensors have their own capabilities for mapping and monitoring water pollution of different types, characteristics, and concentrations. This chapter will discuss and elaborate the merits and limitations of these remote sensing techniques for mapping oil pollutants, suspended solid concentrations, algal blooms, and floating plastic waste in marine waters