Minimally Invasive Ablative Therapies for Definitive Treatment of Localized Prostate Cancer in the Primary Setting

Traditionally, the patient with a new diagnosis of localized prostate cancer faces either radical therapy, in the form of surgery or radiation, or active surveillance. A growing subset of these men may not be willing to accept the psychological burden of active surveillance nor the side effects of extirpative or radiation therapy. Local ablative therapies including cryotherapy, high-intensity focused ultrasound, and vascular-targeted photodynamic therapy have emerged as a means for minimally invasive definitive treatment. These treatments are well tolerated with decreased morbidity in association with improvements in technology; however, long-term oncologic efficacy remains to be determined

Phosphorus Concentrations Into A Subtropical Lake Strongly Influence Nitrogen Accumulation, Nitrogen Export, And Chl A Concentrations

We measured water quality monthly for 22 years in water entering, within, and exiting a 65 km(2) shallow polymictic and eutrophic freshwater lake in the northern Gulf of Mexico. Fertilizer use in the watershed is the dominate source of phosphorous (P) going into the lake and controls the lake\u27s P concentrations, but nitrogen (N) fertilizer use was not related to total nitrogen concentration in the lake. Half of the particulate P entering the lake is trapped within it and there is a net accumulation of N that appears to be from the stimulation of nitrogen fixation. The lake\u27s concentration of Chlorophyll a (mu g Chl a l(-1)) and increase in N in the lake was directly related to the concentration of P in water entering the lake. Variations in the Chl a concentration within a freshwater lake downstream are also directly related to the annual use of P fertilizer, but not to N fertilizer use. Reducing agriculture-sourced P runoff will lower (but not eliminate) both the frequency of algal blooms within Lac des Allemands and the amount of N delivered to the estuary

Hurricane Signals In Salt Marsh Sediments: Inorganic Sources And Soil Volume

The inorganic content of 51 dated sediment cores from Mississippi River deltaic plain salt marsh wetlands peaks with the landfall of hurricanes. Variations in the inorganic sediment content demonstrate no temporal coherence with changes in either the Mississippi River suspended matter concentration or discharge, or with wetland losses on this coast. The inorganic matter brought to wetlands during hurricanes is sufficient to account for the accumulated inorganic sediment, and the volume averages 9% of the soil volume. A sediment deficit\u27\u27 hypothesis, which makes a causal connection between a changing inorganic supply and the dramatically high wetland losses on this coast, is therefore rejected. Our results support the hypothesis that wetlands of an undeveloped coast receive the majority of their inorganic sediments from offshore and not from overbank flooding or through crevasses. Restoration and wetland maintenance (prevention) goals should be implemented with this in mind: the coastal wetland losses of the last century along this coast appear to be a consequence of the diminished accumulation of organic matter and not from variations in inorganic sediment loading

Cooperative Carbon Dioxide Adsorption in Alcoholamine- and Alkoxyalkylamine-Functionalized Metal-Organic Frameworks.

A series of structurally diverse alcoholamine- and alkoxyalkylamine-functionalized variants of the metal-organic framework Mg2 (dobpdc) are shown to adsorb CO2 selectively via cooperative chain-forming mechanisms. Solid-state NMR spectra and optimized structures obtained from van der Waals-corrected density functional theory calculations indicate that the adsorption profiles can be attributed to the formation of carbamic acid or ammonium carbamate chains that are stabilized by hydrogen bonding interactions within the framework pores. These findings significantly expand the scope of chemical functionalities that can be utilized to design cooperative CO2 adsorbents, providing further means of optimizing these powerful materials for energy-efficient CO2 separations

Searching for physics beyond the Standard Model through the dipole interaction

The magnetic dipole interaction played a central role in the development of QED, and continued in that role for the Standard Model. The muon anomalous magnetic moment has served as a benchmark for models of new physics, and the present experimental value is larger than the standard-model value by more than three standard deviations. The electric dipole moment (EDM) violates parity ({$P$}) and time-reversal ({$T$}) symmetries, and in the context of the $CPT$ theorem, the combination of charge conjugation and parity ($CP$). Since a new source of {$CP$} violation outside of that observed in the $K$ and $B$ meson systems is needed to help explain the baryon asymmetry of the universe, searches for EDMs are being carried out worldwide on a number of systems. The standard-model value of the EDM is immeasurably small, so any evidence for an EDM would signify the observation of new physics. Unique opportunities exist for EDM searches using polarized proton, deuteron or muon beams in storage rings. This talk will provide an overview of the theory of dipole moments, and the relevant experiments. The connection to the transition dipole moment that could produce lepton flavor violating interactions such as $\mu^+ \rightarrow e^+ \gamma$ is also mentioned.Comment: Invited Plenary talk at the 19th International Spin Physics Symposium, Juelic

Report of Feasibility Study Task Force for Marietta Truck Growers Association

Exact date of working paper unknown

Quantifying Stock Price Response to Demand Fluctuations

We address the question of how stock prices respond to changes in demand. We quantify the relations between price change $G$ over a time interval $\Delta t$ and two different measures of demand fluctuations: (a) $\Phi$, defined as the difference between the number of buyer-initiated and seller-initiated trades, and (b) $\Omega$, defined as the difference in number of shares traded in buyer and seller initiated trades. We find that the conditional expectations $<G >_{\Omega}$ and $_{\Phi}$ of price change for a given $\Omega$ or $\Phi$ are both concave. We find that large price fluctuations occur when demand is very small --- a fact which is reminiscent of large fluctuations that occur at critical points in spin systems, where the divergent nature of the response function leads to large fluctuations.Comment: 4 pages (multicol fomat, revtex