Shock Metamorphism in Impact Melt Rocks from the Gow Lake Impact Structure, Saskatchewan, Canada

Meteorite impact craters are the dominant surface feature on most terrestrial planetary bodies [1] and are gathering increased interest with the continued exploration of the Solar System. It is worth, then, taking a fresh look at impact craters on Earth, in particular those which have not yet been studied in great detail, like Gow Lake, in order to see if new techniques will shed light on some of the remaining questions about them

Quasiballistic correction to the density of states in three-dimensional metal

We study the exchange correction to the density of states in the three-dimensional metal near the Fermi energy. In the ballistic limit, when the distance to the Fermi level exceeds the inverse transport relaxation time $1/\tau$, we find the correction linear in the distance from the Fermi level. By a large parameter $\epsilon_{\rm F} \tau$ this ballistic correction exceeds the diffusive correction obtained earlier.Comment: 2 pages, 1 figur

Experimental Impacts into Feldspar Phenocrysts

Meteorite impact craters are the dominant surface feature on most terrestrial planetary bodies [1]. The extreme temperatures and pressures generated by hypervelocity impact events produce a variety of microscopic shock metamorphic effects in minerals, as well as non-exclusive shock-related features such as pervasive fracturing and brecciation.<p></p> Studies of shock effects in feldspar group minerals have been limited due to the the comparatively rapid rate at which feldspars weather, and the complexity of their microtextures which renders them difficult to study using conventional optical techniques. However, feldspars are becoming increasingly investigated for use as shock barometers due to their importance in planetary studies and meteoritics, where rocks often contain little or no quartz [e.g., 2]. This provides the motivation to examine more closely the effects of high-velocity impact of a projectile, in the method of [3], into a feldspathic target, in order to the resultant microstructural variation.<p></p&gt

A Method for Predicting Steady-state Rate of Skin Penetration In Vivo

A simple in vivo method was proposed for predicting the steady-state rate of penetration of drugs across the stratum corneum. Both the diffusion coefficient and the partition coefficient in the stratum corneum can be determined by the amounts of drug in the stratum corneum at two time intervals under transient conditions after transdermal drug application. The amount of drug entering the stratum corneum is determined by 20 strippings with an adhesive tape. The steady-state rate of penetration was then calculated for the thickness of the stratum corneum and the concentration of the donor solution. The steady-state rates of penetration of ascorbic acid and estradiol across hairless mouse skin were evaluated from this in vivo approach and compared with those obtained from in vitro penetration experiment using excised hairless mouse skin. The data confirmed that the proposed in vivo method can predict the steady-state rate of penetration of these drugs across the stratum corneum in normal skin

Synthesis and bioactivity of a conjugate composed of green tea catechins and hyaluronic acid

(-)-Epigallocatechin-3-gallate (EGCG) is a green tea polyphenol that has several biological activities, including anti-cancer activity and anti-inflammation. Hyaluronic acid (HA) is a naturally-occurring polysaccharide that is widely used as a biomaterial for drug delivery and tissue engineering due to its viscoelastic, biocompatible and biodegradable properties. By conjugating HA with EGCG, the resulting HA-EGCG conjugate is expected to exhibit not only the inherent properties of HA but also the bioactivities of EGCG. Toward this end, we report the synthesis of an amine-functionalized EGCG as an intermediate compound for conjugation to HA. EGCG was reacted with 2,2-diethoxyethylamine (DA) under acidic conditions, forming ethylamine-bridged EGCG dimers. The EGCG dimers were composed of four isomers, which were characterized by HPLC, high-resolution mass spectrometry and NMR spectroscopy. The amine-functionalized EGCG dimers were conjugated to hyaluronic acid (HA) through the formation of amide bonds. HA-EGCG conjugates demonstrated several bioactivities which were not present in unmodified HA, including resistance to hyaluronidase-mediated degradation, inhibition of cell growth and scavenging of radicals. The potential applications of HA-EGCG conjugates are discussed

Coulomb gap in one-dimensional disordered electronic systems

We study a one-dimensional system of spinless electrons in the presence of a long-range Coulomb interaction (LRCI) and a random chemical potential at each site. We first present a Tomonaga-Luttinger liquid (TLL) description of the system. We use the bosonization technique followed by the replica trick to average over the quenched randomness. An expression for the localization length of the system is then obtained using the renormalization group method and also a physical argument. We then find the density of states for different values of the energy; we get different expressions depending on whether the energy is larger than or smaller than the inverse of the localization length. We work in the limit of weak disorder where the localization length is very large; at that length scale, the LRCI has the effect of reducing the interaction parameter K of the TLL to a value much smaller than the noninteracting value of unity.Comment: Revtex, 6 pages, no figures; discussions have been expanded in several place

ALGAE TO ALKANES

Once considered infeasible and unviable, recently there has been renewed interest in the development of algae-derived transportation fuels. Currently, there are no commercialized algae to fuel ventures, and much debate is centered on the economic viability of such a process. Research conducted by NASA, among others, has expressed skepticism that terrestrially cultivated algae can ever compete with conventional fuels. The purpose of this project is to evaluate the economic feasibility of an algae-to-fuel venture that incorporates the state-of-the-art technologies available in the open literature. Our challenge is to produce 20 thousand barrels per day of n-alkane product that meets the current diesel fuel specifications. To arrive at a recommendation, separate models were built for algae cultivation, lipid extraction, and lipid processing at a scale necessary to reach this target. This analysis departs from prior studies on two major fronts. First, this analysis considers OriginOil’s new method of lipid extraction instead of conventional hexane extraction. Second, the objective of the lipid processing module is to produce n-alkanes from triglycerides, as opposed to producing FAME biodiesel. The n-alkane product from this process is comparable to petroleum-based diesel fuels. Thus it can be readily incorporated into existing energy infrastructure as a diesel blending stock or as a feedstock for other processing units in the refinery. Our economic analysis shows that an algae-to-fuel venture is profitable if the fuel is sold at $3/gallon, the current price of diesel. However, the commercialization of such a process is difficult due to the large total capital investment. At$2.2 billion, the capital investment of algae cultivation is nearly 40 times that of processing, which results in annual depreciation and fixed costs of nearly half of the revenue. Investors would be hesitant to invest such a large amount of money in an algae cultivation process where there is high uncertainty in the cost requirements. Algae-to-fuel economics can be improved by realizing higher value uses of the algae biomass. Biomass composes of over half of algae product, and their potential uses in pharmaceuticals, chemicals, and biomass power generation far surpass their value as animal feed. Proposed carbon-cap-and-trade programs may bring additional revenue. Thus, any algae-to-fuel venture should seek to optimize the value of its byproducts. Governments can support algae-to-fuel ventures by offering tax credits or mandating a market for renewable fuels, but the benefits of these measures are unclear. Additional analysis should address the uncertainties of various costs and look to reduce capital investment

Association Between Immigration History and Inflammatory Marker Profiles Among Older Adult Mexican Americans

Foreign-born Hispanics have better cardiometabolic health upon arrival in the US than their US-born counterparts, yet this advantage diminishes as duration of residence in the US increases. Underlying mechanisms explaining this paradox have been understudied. Using data from the Sacramento Area Latino Study on Aging (SALSA), this study examined immigration history (immigrant generation and duration of US residence) in relation to biomarkers of inflammation (interleukin-6 (IL-6), soluble forms of type 1 and 2 receptors of tumor necrosis factor-alpha (sTNF-R1 and sTNF-R2), C-reactive protein (CRP), leptin, adiponectin) in a sample of 1,290 predominantly Mexican-origin immigrants. Second and ≥3rd generation immigrants had higher IL-6 and leptin levels than 1st generation immigrants living in the US for less than 15 years (2nd generation percent difference = 45.9; 95% CI: 24.7, 70.7 and 3rd generation percent difference = 41.8; 95% CI: 17.7, 70.4). CRP and sTNF-R1 levels were higher among ≥3rd generation immigrants than 1st generation immigrants with less than 15 years of US residency. Worse inflammatory profiles were observed among Mexican-origin immigrants with longer US immigration histories, independent of health, and behavioral factors. Additional research is warranted to understand the factors that shape trajectories of biological risk across generations of Hispanics

Search for τ→μ+γ\tau\to\mu+\gamma decay at Super c−τc -\tau factory

A Monte Carlo study of possible background processes in a search for $\tau \to \mu \gamma$ decay has been performed for conditions of the Super $c-\tau$ factory (CTF) (at a center-of-mass energy 3.686 GeV, 3.77 GeV and 4.17 GeV). The background from $\tau^{+}\tau^{-}$ events has been analysed. Selection criteria for background suppression are suggested and necessary requirements on the detector characteristics have been found. The CTF can successfully compete with the Super B-factory in a search for $\tau \to \mu \gamma$ decay.Comment: 3 pages, 1 figures; contribution to the Proceedings of the PHIPSI11 Workshop (Novosibirsk, Russia, 19-22 September 2011

Anterior Hippocampus and Goal-Directed Spatial Decision Making

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