Massive gravitons dark matter scenario revisited

We reexamine the massive graviton dark matter scenario (MGCDM) which was recently considered as an alternative to dark energy models. When introducing the native and effective equations of state (EoS), it is shown that there is no phantom phase in the evolution toward the far past. Also we show that the past accelerating phase arises from the interaction between massive graviton and cold dark matter.Comment: 13 pages, 6 figure

Metabolite profiling of Neptunia oleracea and correlation with antioxidant and α-glucosidase inhibitory activities using 1H NMR-based metabolomics

Neptunia oleracea is a plant consumed as vegetable and used as a traditional herb to treat several ailments. This study evaluated metabolite variations among N. oleracea leaf and stem subjected to air drying (AD), freeze drying (FD) and oven drying (OD) using proton nuclear magnetic resonance (1H NMR) based metabolomics. The correlation was also studied for the metabolite content with total phenolic content (TPC), DPPH free radical scavenging and α-glucosidase inhibitory activities. A total of 18 metabolites were identified from N. oleracea extracts, including 10 primary metabolites, 5 flavonoids and 3 phenolic acids using NMR. Ultra-high performance liquid chromatography tandem mass spectrometry analysis (UHPLC-MS/MS) confirmed the presence of the secondary metabolites and revealed the flavonoid derivatives present. All the identified phenolics are first reported from this plant. Multivariate data analysis (MVDA) showed strong correlation between the metabolites with the antioxidant and α-glucosidase inhibitory activities of FD N. oleracea leaves. The compounds suggested to be responsible for the high activity of FD leaves include vitexin-2-O-rhamnoside, catechin, caffeic acid, gallic acid and derivatives of quercetin, kaempferol and myricetin. This study demonstrates that FD N. oleracea leaves are a potential natural source for antioxidant and α-glucosidase inhibitors

Holographic interacting dark energy in the braneworld cosmology

We investigate a model of brane cosmology to find a unified description of the radiation-matter-dark energy universe. It is of the interacting holographic dark energy with a bulk-holographic matter $\chi$. This is a five-dimensional cold dark matter, which plays a role of radiation on the brane. Using the effective equations of state $\omega^{\rm eff}_{\rm \Lambda}$ instead of the native equations of state $\omega_{\rm \Lambda}$, we show that this model cannot accommodate any transition from the dark energy with $\omega^{\rm eff}_{\rm \Lambda}\ge-1$ to the phantom regime $\omega^{\rm eff}_{\rm \Lambda}<-1$. Furthermore, the case of interaction between cold dark matter and five dimensional cold dark matter is considered for completeness. Here we find that the redshift of matter-radiation equality $z_{\rm eq}$ is the same order as $z^{\rm ob}_{\rm eq}=2.4\times10^{4} \Omega_{\rm m}h^2$. Finally, we obtain a general decay rate $\Gamma$ which is suitable for describing all interactions including the interaction between holographic dark energy and cold dark matter.Comment: 17 pages, 4 figure

Hydrodynamic Modeling of a Tropical Tidal River Using the Dynamic Estuary Model (DYNHYD5): A Case Study in Sibu Laut River, Sarawak, Malaysia

Application of the Dynamic Estuary Model (DYNHYD5) in a tropical tidal river is limited. The successfully calibrated and validated hydrodynamic model is valuable in subsequent water quality simulation for environmental management. Hence, a hydrodynamic modeling approach using the DYNHYD5 was conducted in a tropical tidal river in Malaysia. Samplings were conducted in the Sibu Laut River to collect the hydrology data for model simulation. The model was calibrated and validated by comparing the simulated flow and mean depth with the field data at different simulation periods of time. The results showed that the model DYNHYD5 was successfully calibrated with channel flows and mean depths and then reproduced with good agreement in validation. The observed and simulated data were linearly correlated (R2 > 0.8) with values of slope γ ranging from 0.891 to 1.204 in both calibration and validation. The Nash–Sutcliffe coefficient of efficiency (NSE) of more than 0.7 in both calibration and validation also indicated satisfactory comparison between the observed and simulated data. The result indicated that the application of the DYNHYD5 is feasible in a tropical tidal river in Malaysia

Antioxidant and α-glucosidase inhibitory activities of the leaf and stem of selected traditional medicinal plants

The study was aimed to determine the antioxidant and α-glucosidase inhibition activities of the stem and leaf of five different traditional medicinal plants. The studied plants exhibited varied antioxidant and α-glucosidase inhibition activities. The antioxidant activities of the plants were determined through their free radical scavenging capabilities using DPPH assay. The most potent antioxidant activity was demonstrated by Neptunia oleracea with an IC50 of 35.45 and 29.72 μg/mL for leaf and stem, respectively. For α-glucosidase inhibition activity, Neptunia oleracea exhibited potential α-glucosidase inhibition activity with IC50 value of 19.09 and 19.74 μg/mL for leaf and stem, respectively. The highest total phenolic content (TPC) was also marked in Neptunia oleracea leaf and stem with value of 40.88 and 21.21 mg GAE/g dry weight, respectively. The results also showed that Strobilanthes crispus collected from two different locations possessed different levels of phenolic content, antioxidant and α-glucosidase inhibition activities. The study revealed that phenolic compounds could be the main contributors to the antioxidant and α-glucosidase inhibition activities with R values of 78.9 and 67.4%, respectively. In addition, antioxidant and α-glucosidase were positively correlated (R = 81.9%). Neptunia oleracea could be suggested as a potential natural source of antioxidant and antidiabetic compounds that can be used for the prevention or treatment of diabetes

BPS Dynamics of Triple (p,q) String Junction

We study dynamics of triple junction of (p,q) strings in Type IIB string theory. We probe tension and mass density of (p,q) strings by studying harmonic fluctuations of the triple junction. We show that they agree perfectly with BPS formula provided suitable geometric interpretation of the junction is given. We provide a precise statement of BPS limit and force-balance property. At weak coupling and sufficiently dense limit, we argue that (p,q)-string embedded in string network is a `wiggly string', whose low-energy dynamics can be described via renormalization group evolved, smooth effective non-relativistic string. We also suggest the possibility that, upon Type IIB strings are promoted to M-theory membrane, there can exist `evanescent' bound-states at triple junction in the continuum.Comment: 11 pages, Latex, 3 figures, typos correcte

Assessment of water quality of Batang Rajang at Pelagus Area, Sarawak, Malaysia

This study was carried out to examine the water quality of Batang Rajang at Pelagus area, Sarawak, Malaysia. Water quality was determined at 12 stations along Batang Rajang and its tributaries in terms of in-situ and ex-situ water quality parameters. The results showed that most stations at main river were categorized as slightly polluted while most tributaries were clean according to the Water Quality Index. The river is suffering from organic pollution where almost all stations along the river contained high chemical oxygen demand (≈ 43.1 mg/L) and total ammonia nitrogen (≈ 0.520 mg/L) and were classified as Class III and IV at most of the stations. High suspended solids (218.3 mg/L) and low dissolved oxygen (4.6 mg/L) were observed at the main river. The low dissolved oxygen content from the Bakun dam upstream of the study area has an impact on the river particularly during dry season where DO dropped below the minimum required for sensitive aquatic organisms. As seven tributaries are within Class II indicating healthy freshwater ecosystems, they should be conserved as habitats for sensitive aquatic organisms. Conversely, proper management need to be initiated in particular, Sungai Merit tributary and the main river where DO were below the minimum required for sensitive aquatic organisms

Comparison of partial least squares and random forests for evaluating relationship between phenolics and bioactivities of Neptunia oleracea

Background: Neptunia oleracea is a plant consumed as a vegetable and which has been used as a folk remedy for several diseases. Herein, two regression models (partial least squares, PLS; and random forest, RF) in a metabolomics approach were compared and applied to the evaluation of the relationship between phenolics and bioactivities of N. oleracea. In addition, the effects of different extraction conditions on the phenolic constituents were assessed by pattern recognition analysis. Results: Comparison of the PLS and RF showed that RF exhibited poorer generalization and hence poorer predictive performance. Both the regression coefficient of PLS and the variable importance of RF revealed that quercetin and kaempferol derivatives, caffeic acid and vitexin-2-O-rhamnoside were significant towards the tested bioactivities. Furthermore, principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA) results showed that sonication and absolute ethanol are the preferable extraction method and ethanol ratio, respectively, to produce N. oleracea extracts with high phenolic levels and therefore high DPPH scavenging and α-glucosidase inhibitory activities. Conclusion: Both PLS and RF are useful regression models in metabolomics studies. This work provides insight into the performance of different multivariate data analysis tools and the effects of different extraction conditions on the extraction of desired phenolics from plants