Lubricant degradation, transport and the effect of extended oil drain intervals on piston assembly tribology

There are ever increasing demands on lubricant manufacturers to meet governmental legislation and customer needs by improving fuel economy, engine durability and exhaust system compatibility as shown by the introduction of GF4 and move towards GF5 specification oils. This has created an ever increasing need to understand how oil degrades in an engine and how this degraded oil affects piston assembly tribology. This review conference paper will give an overview of a collaborative project that has been undertaken to further enhance the understanding of how lubricant degrades in an operating engine, its transport through the engine and effect upon piston assembly tribology

Extraction and tribological investigation of top piston ring zone oil from a gasoline engine

With tightening emission regulations, increased expected fuel economy, and longer drain intervals impacting on lubricant formulation, greater understanding of how oil degrades in an automotive engine is becoming ever more important. Equally significant is the effect that this degraded lubricant has on the tribological operation of the engine, particularly its overall internal friction and component wear. In a previous paper, four tests to degrade oil in a single cylinder engine were reported [1]. These tests were set up such that the lubricating oil was degraded in the ring pack before returning to the sump, where it was sampled and chemical and rheological analysis undertaken. This paper reports the extension of this work using the same Hydra engine and describes how oil has additionally been extracted from the rear of the top piston ring during engine operation. This extracted oil has then been subjected to similar analysis as the sump oil samples in the previous tests, along with additional analysis to look at the tribological properties of the oil using tribometers. The results clearly show significant differences in the rheological, tribological, and chemical properties of the fresh oil and used sump oil samples when compared with the top ring zone (TRZ) oil samples, particularly the effect of load on the levels of volatiles present in the TRZ samples and their effect on traction and friction coefficient values during tribological testing

Variational Integrators for Almost-Integrable Systems

We construct several variational integrators--integrators based on a discrete variational principle--for systems with Lagrangians of the form L = L_A + epsilon L_B, with epsilon << 1, where L_A describes an integrable system. These integrators exploit that epsilon << 1 to increase their accuracy by constructing discrete Lagrangians based on the assumption that the integrator trajectory is close to that of the integrable system. Several of the integrators we present are equivalent to well-known symplectic integrators for the equivalent perturbed Hamiltonian systems, but their construction and error analysis is significantly simpler in the variational framework. One novel method we present, involving a weighted time-averaging of the perturbing terms, removes all errors from the integration at O(epsilon). This last method is implicit, and involves evaluating a potentially expensive time-integral, but for some systems and some error tolerances it can significantly outperform traditional simulation methods.Comment: 14 pages, 4 figures. Version 2: added informative example; as accepted by Celestial Mechanics and Dynamical Astronom

Boundary Action of N=2 Super-Liouville Theory

We derive a boundary action of N=2 super-Liouville theory which preserves both N=2 supersymmetry and conformal symmetry by imposing explicitly $T={\bar T}$ and $G={\bar G}$. The resulting boundary action shows a new duality symmetry.Comment: 15 pages; One reference is adde

Prognostic utility of ADAMTS13 activity for the atypical hemolytic uremic syndrome (aHUS) and comparison of complement serology between aHUS and thrombotic thrombocytopenic purpura

Background Atypical hemolytic uremic syndrome (aHUS) involves dysregulation of the complement system, but whether this also occurs in thrombotic thrombocytopenic purpura (TTP) remains unclear. Although these conditions are difficult to differentiate clinically, TTP can be distinguished by low (<10%) ADAMTS13 activity. The aim was to identify the differences in complement activation products between TTP and aHUS and investigate ADAMTS13 activity as a prognostic factor in aHUS. Methods We analyzed patients with thrombotic microangiopathy diagnosed as TTP (N=48) or aHUS (N=50), selected from a Korean registry (N=551). Complement activation products in the plasma samples collected from the patients prior to treatment and in 40 healthy controls were measured by ELISA. Results The levels of generalized (C3a), alternate (factor Bb), and terminal (C5a and C5b-9) markers were significantly higher (all P<0.01) in the patients than in the healthy controls. Only the factor Bb levels significantly differed (P=0.008) between the two disease groups. In aHUS patients, high normal ADAMTS13 activity (≥77%) was associated with improved treatment response (OR, 6.769; 95% CI, 1.605–28.542; P=0.005), remission (OR, 6.000; 95% CI, 1.693–21.262; P=0.004), exacerbation (OR, 0.242; 95% CI, 0.064–0.916; P=0.031), and disease-associated mortality rates (OR, 0.155; 95% CI, 0.029–0.813; P=0.017). Conclusion These data suggest that complement biomarkers, except factor Bb, are similarly activated in TTP and aHUS patients, and ADAMTS13 activity can predict the treatment response and outcome in aHUS patients

Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants

Background UK Biobank is a well-characterised cohort of over 500 000 participants that offers unique opportunities to investigate multiple diseases and risk factors. Aims An online mental health questionnaire completed by UK Biobank participants was expected to expand the potential for research into mental disorders. Method An expert working group designed the questionnaire, using established measures where possible, and consulting with a patient group regarding acceptability. Case definitions were defined using operational criteria for lifetime depression, mania, anxiety disorder, psychotic-like experiences and self-harm, as well as current post-traumatic stress and alcohol use disorders. Results 157 366 completed online questionnaires were available by August 2017. Comparison of self-reported diagnosed mental disorder with a contemporary study shows a similar prevalence, despite respondents being of higher average socioeconomic status than the general population across a range of indicators. Thirty-five per cent (55 750) of participants had at least one defined syndrome, of which lifetime depression was the most common at 24% (37 434). There was extensive comorbidity among the syndromes. Mental disorders were associated with high neuroticism score, adverse life events and long-term illness; addiction and bipolar affective disorder in particular were associated with measures of deprivation. Conclusions The questionnaire represents a very large mental health survey in itself, and the results presented here show high face validity, although caution is needed owing to selection bias. Built into UK Biobank, these data intersect with other health data to offer unparalleled potential for crosscutting biomedical research involving mental health

Molecular biology of the WWOX gene that spans chromosomal fragile site FRA16D

It is now more than 20 years since the FRA16D common chromosomal fragile site was characterised and the WWOX gene spanning this site was identified. In this time, much information has been discovered about its contribution to disease; however, the normal biological role of WWOX is not yet clear. Experiments leading to the identification of the WWOX gene are recounted, revealing enigmatic relationships between the fragile site, its gene and the encoded protein. We also highlight research mainly using the genetically tractable model organism Drosophila melanogaster that has shed light on the integral role of WWOX in metabolism. In addition to this role, there are some particularly outstanding questions that remain regarding WWOX, its gene and its chromosomal location. This review, therefore, also aims to highlight two unanswered questions. Firstly, what is the biological relationship between the WWOX gene and the FRA16D common chromosomal fragile site that is located within one of its very large introns? Secondly, what is the actual substrate and product of the WWOX enzyme activity? It is likely that understanding the normal role of WWOX and its relationship to chromosomal fragility are necessary in order to understand how the perturbation of these normal roles results in disease.Cheng Shoou Lee, Amanda Choo, Sonia Dayan, Robert I. Richards and Louise V. O’Keef

r-modes in Relativistic Superfluid Stars

We discuss the modal properties of the $r$-modes of relativistic superfluid neutron stars, taking account of the entrainment effects between superfluids. In this paper, the neutron stars are assumed to be filled with neutron and proton superfluids and the strength of the entrainment effects between the superfluids are represented by a single parameter $\eta$. We find that the basic properties of the $r$-modes in a relativistic superfluid star are very similar to those found for a Newtonian superfluid star. The $r$-modes of a relativistic superfluid star are split into two families, ordinary fluid-like $r$-modes ($r^o$-mode) and superfluid-like $r$-modes ($r^s$-mode). The two superfluids counter-move for the $r^s$-modes, while they co-move for the $r^o$-modes. For the $r^o$-modes, the quantity $\kappa\equiv\sigma/\Omega+m$ is almost independent of the entrainment parameter $\eta$, where $m$ and $\sigma$ are the azimuthal wave number and the oscillation frequency observed by an inertial observer at spatial infinity, respectively. For the $r^s$-modes, on the other hand, $\kappa$ almost linearly increases with increasing $\eta$. It is also found that the radiation driven instability due to the $r^s$-modes is much weaker than that of the $r^o$-modes because the matter current associated with the axial parity perturbations almost completely vanishes.Comment: 14 pages, 4 figures. To appear in Physical Review

Diffusion Time-Scale Invariance, Markovization Processes and Memory Effects in Lennard-Jones Liquids

We report the results of calculation of diffusion coefficients for Lennard-Jones liquids, based on the idea of time-scale invariance of relaxation processes in liquids. The results were compared with the molecular dynamics data for Lennard-Jones system and a good agreement of our theory with these data over a wide range of densities and temperatures was obtained. By calculations of the non-Markovity parameter we have estimated numerically statistical memory effects of diffusion in detail.Comment: 10 pages, 3 figure