An Open, Large-Scale, Collaborative Effort to Estimate the Reproducibility of Psychological Science

Reproducibility is a defining feature of science. However, because of strong incentives for innovation and weak incentives for confirmation, direct replication is rarely practiced or published. The Reproducibility Project is an open, large-scale, collaborative effort to systematically examine the rate and predictors of reproducibility in psychological science. So far, 72 volunteer researchers from 41 institutions have organized to openly and transparently replicate studies published in three prominent psychological journals in 2008. Multiple methods will be used to evaluate the findings, calculate an empirical rate of replication, and investigate factors that predict reproducibility. Whatever the result, a better understanding of reproducibility will ultimately improve confidence in scientific methodology and findings

FeelTheNews: Augmenting affective perceptions of news videos with thermal and vibrotactile stimulation

Emotion plays a key role in the emerging wave of immersive, multi-sensory audience news engagement experiences. Since emotions can be triggered by somatosensory feedback, in this work we explore how augmenting news video watching with haptics can influence affective perceptions of news. Using a mixed-methods approach, we design and evaluate FeelTheNews, a prototype that combines vibrotactile and thermal stimulation (Matching, 70Hz/20° C, 200Hz/40° C) during news video watching. In a within-subjects study (N=20), we investigate the effects of haptic stimulation and video valence on perceived valence, emotion intensity, comfort, and overall haptic experiences. Findings showed: (a) news valence and emotion intensity ratings were not affected by haptics, (b) no stimulation was more comfortable than including stimulation, (c) attention and engagement with the news can override haptic sensations, and (d) users’ perceived agency over their reactions is critical to avoid distrust. We contribute cautionary insights for haptic augmentation of the news watching experience

Systemic induction of senescence in young mice after single heterochronic blood exchange

AbstactAgeing is the largest risk factor for many chronic diseases. Studies of heterochronic parabiosis, substantiated by blood exchange and old plasma dilution, show that old-age-related factors are systemically propagated and have pro-geronic effects in young mice. However, the underlying mechanisms how bloodborne factors promote ageing remain largely unknown. Here, using heterochronic blood exchange in male mice, we show that aged mouse blood induces cell and tissue senescence in young animals after one single exchange. This induction of senescence is abrogated if old animals are treated with senolytic drugs before blood exchange, therefore attenuating the pro-geronic influence of old blood on young mice. Hence, cellular senescence is neither simply a response to stress and damage that increases with age, nor a chronological cell-intrinsic phenomenon. Instead, senescence quickly and robustly spreads to young mice from old blood. Clearing senescence cells that accumulate with age rejuvenates old circulating blood and improves the health of multiple tissues