Московский опыт в творчестве Захи Хадид

Zaha Hadid’s works are represented in the article by the Dominion Tower Office Building – the only one project of hers realized in Moscow so far. Zaha Hadid’s early creative work was inspired by Russian avant-gardists and constructivists. The article shows the impact it had on the Moscow project.Статья посвящена творчеству Захи Хадид, представленному единственным реализованным в Москве проектом бизнес-центра Dominion Tower. Показано, как на этом проекте отразилось влияние на Заху Хадид творчества русских авангардистов и конструктивистов

Lyceum coworking as a motivator for students to work together

The widespread adoption of the psychology of sustainable development shows that it encourages people to take sustainable actions in their daily lives, as well as how these actions affect their well-being and connection with the environment. This study dedicated to on the importance of a sustainable lifestyle, as well as the thought process underlying our decisions, and how this affects the quality training of future teachers who can be able be responsible not only for their work, but also for the amount of work performed by the whole team. All this is possible only if there are innovative laboratories to stimulate cognitive activity and support the development of the innovative potential of the educational organization itself. Despite the growing attention to the role of coworking in business, there are currently no publications about its organization and functioning within an educational organization. There is no comprehensive understanding of its importance as innovative spaces for the development and maintenance of the innovative space of organizations with the possibility of developing the younger generation. For this reason, the innovative laboratory on the basis of the lyceum (lyceum coworking) is a tool for the formation of motivation for teaching physics, which allows solving problems together in project activities. In particular, the study actualizes the concept of "joint activity" as a necessary component of the functioning of innovation laboratories

Applying benchmarking tool in assessment financial safety of organization

The aim of paper is to assess financial safety of organization using benchmarking method which was initially involved in business practices such companies as Xerox and Hewlett-Packard. Our research addresses using benchmarking relating to assessment of financial state of three Russian oil companies in order to develop a set of suggestions leading to desirable financial state. Proposed technique for assessment financial safety implies next steps: identifying key factors affecting the financial state of company, the choice of financial safety indicators by means of correlation analysis, a calculation of integral indexes of financial safety, development of guidance for decisions making.  The next fundamental indicators of financial safety are examined - financial independence ratio, leverage ratio, accounts receivable turnover ratio, accounts payable turnover ratio, returns on assets, return on borrowed capital. To improve financial ratios the matrix of management decisions was elaborated

THE IMPACT OF DEMOGRAPHIC RESILIENCE ON THE ECONOMIC DEVELOPMENT OF COUNTRIES (ON THE EXAMPLE OF THE VISEGRAD GROUP COUNTRIES)

The population, its physical well-being and development is a defining feature of society, the basis of the state's strength. Taking into account demographic trends is important in shaping strategies for economic development. Understanding the impact of population changes on the labour market, consumer demand, investment climate, and population expenditures is crucial for creating a sustainable and competitive economy. The demographic resilience of a country is determined by its ability to ensure quantitative and qualitative reproduction of demographic structures at various stages of historical development. Demographic resilience is a dynamic category that changes over time, and the level of a country's demographic resilience is defined by the parameters of its functioning. The level of demographic resilience depends on trends in population reproduction and mortality, demographic dependency, migration processes, gender equality, and the development of the healthcare system. Under these conditions, the assessment of the demographic resilience of the Visegrad Group countries was carried out in the context of these specified directions, allowing for the calculation of an indicator of the level of demographic resilience for Poland, the Czech Republic, Slovakia, and Hungary. The analysis of the level of demographic resilience in the Visegrad Group countries indicates an average value. However, the analysis of reproduction and mortality indicators suggests the presence of demographic crises in these countries. Population decline, falling birth rates, and an increase in mortality rates are key characteristics of the demographic crisis. Therefore, the Visegrad Group countries need to implement effective policy measures to ensure the development and efficient use of human capital, as well as social protection for migrants, refugees, and citizens, at a sufficient level through a politically and financially stable system

Professional Training of Future Green Economy Specialists and Strategic Priorities for Sustainable Subsurface Management

AbstractOn the brink of the third millennium humanity has been showing a special interest in the environment. This article provides definitions of the term “sustainable development” and explains how to achieve it by implementing the new development model known as “the green economy”; it also shows the role and place of education in the overall set of tools and mechanisms that assist in transitioning to the green economy principles. The authors substantiate the importance and necessity of preparing specialists for the green economy as the first step towards its implementation. They give an example of an interdisciplinary training module designed to prepare future specialists. This module can easily be integrated in the student's individual training course. We describe the advantages and benefits of the suggested educational module

Psychological and social adaptive orientation in the teaching of first-year students

The article is devoted to the problem of adaptation of first–year students - future teachers to university education. The concept of «adaptation of students», factors and a set of problems of a first-year student are considered. The analysis of the component of the psychological and social adaptability of orientation in the educational process when studying at a university is presented. The results of the survey and diagnosis are to identify the difficulties experienced by future teachers in the first year of study, in order to create conditions for adaptation to the university format of educational and cognitive activity

Educational coworking as a means of developing sustainable mobility of students

Sustainable mobility of students includes a set of actions aimed at bringing to a clean ecological lifestyle. This study is devoted to the development of sustainable mobility of students by means of coworking, the influence of this space on the training of future personnel who are able to master new technologies, apply them to solve practical problems, formulate and solve hypotheses, defend their point of view, work in a team, take responsibility not only for themselves, but also for team members. All this is possible only if there are innovative laboratories that stimulate the joint cognitive activity of students by developing the innovative potential of an educational organization by means of coworking, which motivates collaborations. Despite the increasing attention to the role of sustainable mobility used in the transport sector, at the moment there are few publications devoted to its organization and their functioning in the context of an educational organization. There is no comprehensive understanding of its importance as a mobile space for the development and maintenance of innovations in educational institutions with the possibility of developing the younger generation. That is why the innovation laboratory at the Lyceum is a tool for the formation of motivation to learn natural sciences, which allows them to jointly solve tasks within the framework of project activities, developing sustainable mobility for them. The coworking model of work in the lyceum environment not only contributes to the development of sustainable mobility, but also develops key skills in all participants of the educational process, such as self-organization, time management, presentation and communication skills

Wolf Creek Cold Regions Model Set-up, Parameterisation and Modelling Summary

Non-Peer ReviewedWolf Creek Research Basin is in the Upper Yukon River Basin near Whitehorse, Yukon and is representative of headwaters in the northern Coast Mountains. It was established in 1993 to better develop northern hydrological models, and related hydrological process, ecosystem and climate science. Yukon Environment maintains Wolf Creek hydrometeorological and hydrometric stations and conducts regular snow surveys in the basin. A number of hydrological models have been tested on Wolf Creek and all have had great difficulty in simulating the cold regions hydrological processes that dominate its streamflow response to snowmelt and rainfall events. Developments in understanding hydrological processes and their interaction with terrestrial ecosystems and climate at Wolf Creek have lead to the development of the Cold Regions Hydrological Model (CRHM) by a consortium of scientists led by the University of Saskatchewan and Environment Canada. CRHM comprehensively incorporates the blowing snow, intercepted snow, sublimation, melt energetics, infiltration to frozen soils, organic terrain runoff and other cold regions hydrological phenomenon and discretizes the catchment on a hydrological response unit basis for applying water and energy balance calculations. The model is intended for prediction of ungauged basins with parameter selection from physically measurable properties of the river basin or regional transference of calibrated values. In Russia, a long tradition of cold regions hydrological research has led to the development of the Hydrograph model by the State Hydrological Institute, St. Petersburg. The Hydrograph model contains several promising innovations regarding the formation and routing of runoff, discretizes the basin using hydrological response units and addresses some (but not all) cold regions hydrological processes. Hydrograph parameter selection is made from both physically measured properties and those that are calibrated, but the calibrations can be easily regionalized. Test simulations of runoff processes using CRHM and Hydrograph for Wolf Creek Research Basin was undertaken using data archives that had been assembled and cleaned up in a related project by the University of Saskatchewan. The test simulations are a demonstration of model capabilities and a way to gain familiarity with the basin, its characteristics and data and to better compare model features. Data available included a GIS database of basin characteristics (topography and vegetation distribution) and the hydrometeorological and hydrometric observational dataset from Yukon Environment. The sub-surface hydrology presented a formidable unknown in parameterising the model. Hydrograph performed well in initial simulations of the basin hydrograph for multi-year runs. Several issues with observational data quality created substantial uncertainty in evaluating the model runs

Development, production and characterization of SARS-CoV-2 virus-like particles (Coronaviridae: <i>Orthocoronavirinae: Betacoronavirus: Sarbecovirus</i>)

Introduction. The COVID-19 pandemic caused by SARS-CoV-2 has created serious health problems worldwide. The most effective way to prevent the occurrence of new epidemic outbreaks is vaccination. One of the modern and effective approaches to vaccine development is the use of virus-like particles (VLPs). The aim of the study is to develop a technology for production of VLP based on recombinant SARS-CoV-2 proteins (E, M, N and S) in insect cells. Materials and methods. Synthetic genes encoding coronavirus proteins E, M, N and S were used. VLP with various surface proteins of strains similar to the Wuhan virus, Delta, Alpha and Omicron were developed and cloned into the pFastBac plasmid. The proteins were synthesized in the baculovirus expression system and assembled into VLP in the portable Trichoplusia ni cell. The presence of insertion in the baculovirus genome was determined by PCR. ELISA and immunoblotting were used to study the antigenic activity of VLP. VLP purification was performed by ultracentrifugation using 20% sucrose. Morphology was assessed using electron microscopy and dynamic light scattering. Results. VLPs consisting of recombinant SARS-CoV-2 proteins (S, M, E and N) were obtained and characterized. The specific binding of antigenic determinants in synthesized VLPs with antibodies to SARS-CoV-2 proteins has been demonstrated. The immunogenic properties of VLPs have been studied. Conclusion. The production and purification of recombinant VLPs consisting of full-length SARS-CoV-2 proteins with a universal set of surface antigens have been developed and optimized. Self-assembling particles that mimic the coronavirus virion induce a specific immune response against SARS-CoV-2

An Integrated Approach to Rapid Diagnosis of Tuberculosis and Multidrug Resistance Using Liquid Culture and Molecular Methods in Russia

Objective: To analyse the feasibility, cost and performance of rapid tuberculosis (TB) molecular and culture systems, in a high multidrug-resistant TB (MDR TB) middle-income region (Samara, Russia) and provide evidence for WHO policy change. Methods: Performance and cost evaluation was conducted to compare the BACTEC™ MGIT™ 960 system for culture and drug susceptibility testing (DST) and molecular systems for TB diagnosis, resistance to isoniazid and rifampin, and MDR TB identification compared to conventional Lowenstein-Jensen culture assays. Findings: 698 consecutive patients (2487 sputum samples) with risk factors for drug-resistant tuberculosis were recruited. Overall M. tuberculosis complex culture positivity rates were 31.6% (787/2487) in MGIT and 27.1% (675/2487) in LJ (90.5% and 83.2% for smear-positive specimens). In total, 809 cultures of M. tuberculosis complex were isolated by any method. Median time to detection was 14 days for MGIT and 36 days for LJ (10 and 33 days for smear positive specimens) and indirect DST in MGIT took 9 days compared to 21 days on LJ. There was good concordance between DST on LJ and MGIT (96.8% for rifampin and 95.6% for isoniazid). Both molecular hybridization assay results correlated well with MGIT DST results, although molecular assays generally yielded higher rates of resistance (by approximately 3% for both isoniazid and rifampin). Conclusion: With effective planning and logistics, the MGIT 960 and molecular based methodologies can be successfully introduced into a reference laboratory setting in a middle incidence country. High rates of MDR TB in the Russian Federation make the introduction of such assays particularly useful. © 2009 Balabanova et al