Environmental aspects of the depreciation of the culturally significant Wall of Cartagena de Indias – Colombia

Among the diverse archeological relics of the past, the Cartagena de Indias Wall is one of the greatest representations of European cultural architecture in South America. To assess the implication of contamination on the depreciation of the culturally significant Wall of Cartagena de Indias - Colombia, a detailed, multi-analytical approach was conducted on components of the wall. Accumulated ultra-fine particles (UFPs) and superficial nano-particles (NPs) containing hazardous elements (HEs) on the wall were identified in an attempt to understand whether atmospheric pollution is hastening the depreciation of the structure itself. Mortar which at one point held the stones together is now weak and has fallen away in places. Irreparable damage is being done by salt spray, acid rain and the site's tropical humid climate. Several HEs and organic compounds found within the local environment are also contributing to the gradual deterioration of the construction. In this study, advanced microscopy analyses have been applied to understand the properties of UFPs and NPs deposited onto the wall's weathered external walls through exposure to atmospheric pollution. Several materials identified by X-Ray Diffraction (XRD) can be detected using high-resolution transmission electron microscopy (HR-TEM) and field emission scanning electron microscope (FE-SEM). The presence of anglesite, gypsum, hematite containing HEs, and several organic compounds modified due to moisture and contamination was found. Black crusts located on the structure could potentially serve as a source of HEs pollution and a probable hazard to not only to the ecosystem but also to human health

Nanoparticles as vectors of other contaminants in estuarine suspended sediments: Natural and real conditions

Studding the behaviour and danger of nanoparticles (NPs, minerals and amorphous phases) in the estuarine ecosystem is presently incomplete by the lack of measureable description of NPs in the ecological conditions, such as suspended-sediments (SS). In the last years, several works have revealed the toxic consequences of ultra-fine and nanoparticulate compounds on diverse systems, raising apprehensions over the nanocontaminants behaviour and destiny in the numerous ecological partitions. The general objective of the manuscript is to explain the geochemical conditions of the LES (Laguna estuarine system, southern Brazil) suspended sediments covering an area around the main South American coal plant, enhancing the creation of future public policies for environmental recovery projects. Subsequently the discharge of nanoparticles and toxic element (TE) in the ecosystem, NPs react with several constituents of the nature and suffers active alteration progressions. Contamination coming from engineering actions, wastewater, are something identifiable, however when these contaminations are accompanied by other contamination sources (e.g. mining and farming) the work gets defaulted. By combining material about the concentration of TE contaminants and NPs occurrences, this work offers novel visions into contaminant contact and the possible effects of such exposure on estuarine systems in Brazil. The results presented here will be useful for different areas of estuaries around the world

Higher Prostate Weight Is Inversely Associated with Gleason Score Upgrading in Radical Prostatectomy Specimens

Background. Protective factors against Gleason upgrading and its impact on outcomes after surgery warrant better definition. Patients and Methods. Consecutive 343 patients were categorized at biopsy (BGS) and prostatectomy (PGS) as Gleason score, ≤6, 7, and ≥8; 94 patients (27.4%) had PSA recurrence, mean followup 80.2 months (median 99). Independent predictors of Gleason upgrading (logistic regression) and disease-free survival (DFS) (Kaplan-Meier, log-rank) were determined. Results. Gleason discordance was 45.7% (37.32% upgrading and 8.45% downgrading). Upgrading risk decreased by 2.4% for each 1 g of prostate weight increment, while it increased by 10.2% for every 1 ng/mL of PSA, 72.0% for every 0.1 unity of PSA density and was 21 times higher for those with BGS 7. Gleason upgrading showed increased clinical stage (P=0.019), higher tumor extent (P=0.009), extraprostatic extension (P=0.04), positive surgical margins (P<0.001), seminal vesicle invasion (P=0.003), less “insignificant” tumors (P<0.001), and also worse DFS, χ2=4.28, df=1, P=0.039. However, when setting the final Gleason score (BGS ≤6 to PGS 7 versus BGS 7 to PGS 7), avoiding allocation bias, DFS impact is not confirmed, χ2=0.40, df=1, P=0.530.Conclusions. Gleason upgrading is substantial and confers worse outcomes. Prostate weight is inversely related to upgrading and its protective effect warrants further evaluation

Higher Prostate Weight Is Inversely Associated With Gleason Score Upgrading In Radical Prostatectomy Specimens.

Background. Protective factors against Gleason upgrading and its impact on outcomes after surgery warrant better definition. Patients and Methods. Consecutive 343 patients were categorized at biopsy (BGS) and prostatectomy (PGS) as Gleason score, ≤6, 7, and ≥8; 94 patients (27.4%) had PSA recurrence, mean followup 80.2 months (median 99). Independent predictors of Gleason upgrading (logistic regression) and disease-free survival (DFS) (Kaplan-Meier, log-rank) were determined. Results. Gleason discordance was 45.7% (37.32% upgrading and 8.45% downgrading). Upgrading risk decreased by 2.4% for each 1 g of prostate weight increment, while it increased by 10.2% for every 1 ng/mL of PSA, 72.0% for every 0.1 unity of PSA density and was 21 times higher for those with BGS 7. Gleason upgrading showed increased clinical stage (P = 0.019), higher tumor extent (P = 0.009), extraprostatic extension (P = 0.04), positive surgical margins (P < 0.001), seminal vesicle invasion (P = 0.003), less insignificant tumors (P < 0.001), and also worse DFS, χ (2) = 4.28, df = 1, P = 0.039. However, when setting the final Gleason score (BGS ≤6 to PGS 7 versus BGS 7 to PGS 7), avoiding allocation bias, DFS impact is not confirmed, χ (2) = 0.40, df = 1, P = 0.530.Conclusions. Gleason upgrading is substantial and confers worse outcomes. Prostate weight is inversely related to upgrading and its protective effect warrants further evaluation.201371042

Active learning in the detection of anomalies in cryptocurrency transactions

The cryptocurrency market has grown significantly, and this quick growth has given rise to scams. It is necessary to put fraud detection mechanisms in place. The challenge of inadequate labeling is addressed in this work, which is a barrier to the training of high-performance supervised classifiers. It aims to lessen the necessity for laborious and time-consuming manual labeling. Some unlabeled data points have labels that are more pertinent and informative for the supervised model to learn from. The viability of utilizing unsupervised anomaly detection algorithms and active learning strategies to build an iterative process of acquiring labeled transactions in a cold start scenario, where there are no initial-labeled transactions, is being investigated. Investigating anomaly detection capabilities for a subset of data that maximizes supervised models’ learning potential is the goal. The anomaly detection algorithms under performed, according to the results. The findings underscore the need that anomaly detection algorithms be reserved for situations involving cold starts. As a result, using active learning techniques would produce better outcomes and supervised machine learning model performance.FCT - Fundação para a Ciência e a Tecnologia(UIDB/00319/2020

Spatiotemporal assessment of particulate matter (PM10 and PM2.5) and ozone in a Caribbean urban coastal city

Air pollution has become a critical issue in urban areas, so a broad understanding of its spatiotemporal characteristics is important to develop public policies. This study analyzes the spatiotemporal variation of atmospheric particulate matter (PM10 and PM2.5) and ozone (O3) in Barranquilla, Colombia from March 2018 to June 2019 in three monitoring stations. The average concentrations observed for the Móvil, Policía, and Tres Avemarías stations, respectively, for PM10: 46.4, 51.4, and 39.7 µg/m3; for PM2.5: 16.1, 18.1, and 15.1 µg/m3 and for O3: 35.0, 26.6, and 33.6 µg/m3. The results indicated spatial and temporal variations between the stations and the pollutants evaluated. The highest PM concentrations were observed in the southern part of the city, while for ozone, higher concentrations were observed in the north. These variations are mainly associated with the influence of local sources in the environment of each site evaluated as well as the meteorological conditions and transport patterns of the study area. This study also verified the existence of differences in the concentrations of the studied pollutants between the dry and rainy seasons and the contribution of local sources as biomass burnings from the Isla Salamanca Natural Park and long-range transport of dust particles from the Sahara Desert. This study provides a scientific baseline for understanding air quality in the city, which enables policy makers to adopt efficient measures that jointly prevent and control pollution

Nanoparticles from evaporite materials in Colombian coal mine drainages

Ultrathin and nanometric materials (minerals and amorphous phases) are detected in transitory deposits of potential hazardous elements (PHEs), especially in acidic coal mine drainages. The main goal of this work was to evaluate the occurrence of PHEs in nanoparticles (NPs) in evaporative structures in coal mining areas with high concentrations of PHEs. The precipitates were sampled in several coal mining areas in Colombia, with the purpose of evaluating the geochemical and environmental structures. In the present work, to better diagnose areas affected by coal mining, an innovative analytical procedure is proposed to define the association between PHEs in mine drainage sediments. The procedure includes the analytical study with X-Ray Diffraction (XRD) and advanced electron microscopy, before and after a series of sequential extractions to separate amorphous, magnetic, and crystalline compounds. Of the three main types of precipitates identified, the yellowish precipitates had the highest amounts of PHEs while the white precipitates had only small amounts of PHEs and the greenish precipitates contained TiO2 nanoparticles. The results from this study will be usable for more than fifty countries that have coal mine drainages