354 research outputs found
Identification of the Red Supergiant Progenitor of Supernova 2005cs: Do the Progenitors of Type II-P Supernovae Have Low Mass?
The stars that end their lives as supernovae (SNe) have been directly
observed in only a handful of cases, due mainly to the extreme difficulty in
identifying them in images obtained prior to the SN explosions. Here we report
the identification of the progenitor for the recent Type II-plateau
(core-collapse) SN 2005cs in pre-explosion archival images of the Whirlpool
Galaxy (M51) obtained with the Hubble Space Telescope (HST) Advanced Camera for
Surveys (ACS). From high-quality ground-based images of the SN from the
Canada-France-Hawaii Telescope, we precisely determine the position of the SN
and are able to isolate the SN progenitor to within 0".04 in the HST/ACS
optical images. We further pinpoint the SN location to within 0".005 from
HST/ACS ultraviolet images of the SN, confirming our progenitor identification.
From photometry of the SN progenitor obtained with the pre-SN ACS images, and
also limits to its brightness in pre-SN HST/NICMOS images, we infer that the
progenitor is a red supergiant star of spectral type K0--M3, with initial mass
7--9 Msun. We also discuss the implications of the SN 2005cs progenitor
identification and its mass estimate. There is an emerging trend that the most
common Type II-plateau SNe originate from low-mass supergiants 8--15 Msun.Comment: Submitted to ApJ. A high resolution version can be found at
http://astron.berkeley.edu/~weidong/sn05cs.p
Global Origin of Mycobacterium tuberculosis in the Midlands, UK
DNA fingerprinting data for 4,207 Mycobacterium tuberculosis isolates were combined with data from a computer program (Origins). Largest population groups were from England (n = 1,031) and India (n = 912), and most prevalent strains were the Euro-American (45%) and East AfricanâIndian (34%) lineages. Combining geographic and molecular data can enhance cluster investigation
A realistic assessment of methods for extracting gene/protein interactions from free text
Background: The automated extraction of gene and/or protein interactions from the literature is one of the most important targets of biomedical text mining research. In this paper we present a realistic evaluation of gene/protein interaction mining relevant to potential non-specialist users. Hence we have specifically avoided methods that are complex to install or require reimplementation, and we coupled our chosen extraction methods with a state-of-the-art biomedical named entity tagger. Results: Our results show: that performance across different evaluation corpora is extremely variable; that the use of tagged (as opposed to gold standard) gene and protein names has a significant impact on performance, with a drop in F-score of over 20 percentage points being commonplace; and that a simple keyword-based benchmark algorithm when coupled with a named entity tagger outperforms two of the tools most widely used to extract gene/protein interactions. Conclusion: In terms of availability, ease of use and performance, the potential non-specialist user community interested in automatically extracting gene and/or protein interactions from free text is poorly served by current tools and systems. The public release of extraction tools that are easy to install and use, and that achieve state-of-art levels of performance should be treated as a high priority by the biomedical text mining community
Vulvovaginal Trichosporonosis
Objective: Isolation of Trichosporon species from vaginal secretions is a rare event, and no data are available on its pathogenic role. A case series is presented to determine the pathogenic role of Trichosporon species in vulvovaginal infections. Methods: We performed a retrospective chart review of patients seen in the W.S.U. Vaginitis Clinic in order to identify patients from whom Trichosporon species were isolated. Results: Between 1986 and 2001, a total of 13 patients had a total of 18 positive vaginal cultures for Trichosporon species. All 18 vaginal isolates were T. inkin. In general, positive vaginal cultures were accompanied by low yeast colony counts. Four out of 18 positive T. inkin cultures were obtained from visits by asymptomatic patients. Of the remaining 14 positive T. inkin cultures from patients with symptoms, nine out of 14 cultures had other diagnoses (Candida albicans, six cases; bacterial vaginosis, two cases; Trichomonas, one case). Five positive T. inkin cultures were obtained from visits at which patients had symptoms and no associated diagnosis. In only one of the five episodes could we establish a clear pathogenic role for Trichosporon. In this case the patient was treated with boric acid and had resolution of symptoms and a negative culture at follow-up. In-vitro susceptibility tests revealed that T. inkin was resistant to flucytosine and susceptible to all topical and oral azoles. Conclusions: T. inkin is occasionally found in vulvovaginal cultures and is usually a non-pathogen. Transient colonization tended to occur in women, usually of AfricanâAmerican origin, with major perturbations in vaginal flora (bacterial vaginosis and trichomoniasis) and increased pH. Pathogenic consequences of Trichosporon colonization appear to be rare
Observations of red-giant variable stars by Aboriginal Australians
Aboriginal Australians carefully observe the properties and positions of
stars, including both overt and subtle changes in their brightness, for
subsistence and social application. These observations are encoded in oral
tradition. I examine two Aboriginal oral traditions from South Australia that
describe the periodic changing brightness in three pulsating, red-giant
variable stars: Betelgeuse (Alpha Orionis), Aldebaran (Alpha Tauri), and
Antares (Alpha Scorpii). The Australian Aboriginal accounts stand as the only
known descriptions of pulsating variable stars in any Indigenous oral tradition
in the world. Researchers examining these oral traditions over the last
century, including anthropologists and astronomers, missed the description of
these stars as being variable in nature as the ethnographic record contained
several misidentifications of stars and celestial objects. Arguably,
ethnographers working on Indigenous Knowledge Systems should have academic
training in both the natural and social sciences.Comment: The Australian Journal of Anthropology (2018
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