Behavioral characterization of serotonin transporter knock-in mouse

International audienc

INVENTORIES AND FIXED INVESTMENT

We model fixed investment incorporating the inventory decision of the firm. Using Dutch listed nonfinancial firms during 1985-2000, we find that the inventory stock is negatively associated with fixed investment. The results suggest that the inventory stock may be used by the firm as a buffer in response to unexpectedly high demand. In addition, the firm may hold the inventory stock as a contingency substitute for the financial source of fixed investment. Copyright Blackwell Publishing Ltd/University of Adelaide and Flinders University of South Australia 2004.

Eletrocirurgia: sistemas mono e bipolar em cirurgia videolaparoscópica

O conhecimento das leis físicas e dos mecanismos de funcionamento da eletrocirurgia são de grande importância para o cirurgião. Lesões por eletrocirurgia em laparoscopia têm sido observadas, e estão associadas ao uso do eletrodo monopolar, com freqüência de 1 a 2 lesões a cada 1000 procedimentos.Com relação ao desenvolvimento de lesão, existem vários fatores que influenciam: densidade da corrente; o tipo de onda e de coagulação usadas, com suas respectivas voltagens; as condições de isolamento dos dispositivos; a ocorrência do fenômeno de capacitância; e os riscos oferecidos pelo uso em pacientes com marcapasso. No sistema bipolar, a densidade de corrente encontrada ao redor de seus eletrodos é bem menor, levando a menos lesões e, ainda, elimina vários dos outros mecanismos lesivos, como a placa de retorno e os citados acima. Vários estudos demonstram, em colecistectomias, apendicectomias, polipectomias e outros, que o índice de complicações com o eletrodo bipolar é significativamente menor.<br>the knowledge of the physical laws and of the mechanisms of functioning of electrosurgery are of great importance for the surgeon. Lesions caused by electrosurgery in laparoscopic procedures have been observed, and are associated with the use of monopolar electrode, with the frequency of 1 to 2 lesions in every 1000 procedures. Concerning the development of the lesions, several factors are involved; current density, the waveform and the type of coagulation used, with its respective voltages; the insulation condition of the devices; the occurrence of the phenomenon of capacitance and the risks involved with the use in patients with pacemakers. In bipolar electrosurgery, the current density produced around the electrodes is much lower, causing less tissue damage and, still, eliminating several of the other mechanims of injury, such as the dispersive electrode and those quoted above. Several studies reveal that the incidence of complications with the use of bipolar electrodes in cholecystectomies, appendicectomies, polypectomies and other procedures is significantly lower

XIPE

XIPE, the X-ray Imaging Polarimetry Explorer, is a mission dedicated to X-ray Astronomy. At the time of writing XIPE is in a competitive phase A as fourth medium size mission of ESA (M4). It promises to reopen the polarimetry window in high energy Astrophysics after more than 4 decades thanks to a detector that efficiently exploits the photoelectric effect and to X-ray optics with large effective area. XIPE uniqueness is time-spectrally-spatially-resolved X-ray polarimetry as a breakthrough in high energy astrophysics and fundamental physics. Indeed the payload consists of three Gas Pixel Detectors at the focus of three X-ray optics with a total effective area larger than one XMM mirror but with a low weight. The payload is compatible with the fairing of the Vega launcher. XIPE is designed as an observatory for X-ray astronomers with 75 % of the time dedicated to a Guest Observer competitive program and it is organized as a consortium across Europe with main contributions from Italy, Germany, Spain, United Kingdom, Poland, Sweden.Peer reviewe