High accuracy 235 U(n,f) data in the resonance energy region

The 235U neutron-induced cross section is widely used as reference cross section for measuring other fission cross sections, but in the resonance region it is not considered as an IAEA standard because of the scarce experimental data covering the full region. In this work, we deal with a new analysis of the experimental data obtained with a detection setup based on parallel plate ionization chambers (PPACs) at the CERN n_TOF facility in the range from 1 eV to 10 keV. The relative cross section has been normalised to the IAEA value in the region between 7.8 and 11 eV, which is claimed as well-known. Comparison with the ENDF/B-VII evaluation and the IAEA reference file from 100 eV to 10 keV are provide

New measurement of exotic decay of 225^{225}Ac by 14^{14}C emission

The branching ratio of $^{225}$Ac decay by emission of $^{14}$C was remeasured under improved experimental conditions by using a radioactive source produced at the ISOLDE mass-separator at CERN and a nuclear track detector technique. The result, B=$\lambda_{^{14}\textrm{C}} / \lambda_{\alpha} = (4.5 \pm 1.4) 10^{-12}$, is consistent with the anomalously high value obtained in the 1993 experiment thus confirming the importance of nuclear structure effects in this exotic decay

Status of the LHC Superconducting Cable Mass Production

Six contracts have been placed with industrial companies for the production of 1200 tons of the superconducting (SC) cables needed for the main dipoles and quadrupoles of the Large Hadron Collider (LHC). In addition, two contracts have been placed for the supply of 470 tons of NbTi and 26 tons of Nb sheets. The main characteristic of the specification is that it is functional. This means that the physical, mechanical and electrical properties of strands and cables are specified without defining the manufacturing processes. Facilities for the high precision measurements of the wire and cable properties have been implemented at CERN, such as strand and cable critical current, copper to superconductor ratio, interstrand resistance, magnetisation, RRR at 4.2 K and 1.9 K. The production has started showing that the highly demanding specifications can be fulfilled. This paper reviews the organisation of the contracts, the test facilities installed at CERN, the various types of measurements and the results of the main physical properties obtained on the first batches. The status of the deliveries is presented

The Tetraspanins CD9 and CD81 Regulate CD9P1-Induced Effects on Cell Migration

CD9P-1 is a cell surface protein with immunoglobulin domains and an unknown function that specifically associates with tetraspanins CD9 and CD81. Overexpression of CD9P-1 in HEK-293 cells induces dramatic changes in cell spreading and migration on various matrices. Experiments using time-lapse videomicroscopy revealed that CD9P-1 expression has led to higher cell motility on collagen I but lower motility on fibronectin through a β1-integrins dependent mechanism. On collagen I, the increase in cell motility induced by CD9P-1 expression was found to involve integrin α2β1 and CD9P-1 was observed to associate with this collagen receptor. The generation of CD9P-1 mutants demonstrated that the transmembrane and the cytoplasmic domains are necessary for inducing effects on cell motility. On the other hand, expression of tetraspanins CD9 or CD81 was shown to reverse the effects of CD9P-1 on cell motility on collagen I or fibronectin with a concomitant association with CD9P-1. Thus, the ratio of expression levels between CD9P-1 and its tetraspanin partners can regulate cell motility

Low energy measurement of the 7Be(p,gamma)8B cross section

We have measured the cross section of the 7Be(p,gamma)8B reaction for E_cm = 185.8 keV, 134.7 keV and 111.7 keV using a radioactive 7Be target (132 mCi). Single and coincidence spectra of beta^+ and alpha particles from 8B and 8Be^* decay, respectively, were measured using a large acceptance spectrometer. The zero energy S factor inferred from these data is 18.5 +/- 2.4 eV b and a weighted mean value of 18.8 +/- 1.7 eV b (theoretical uncertainty included) is deduced when combining this value with our previous results at higher energies.Comment: Accepted for publication in Phys. Rev. Let

Proteomic analysis of nipple aspirate fluid to detect biologic markers of breast cancer.

The early detection of breast cancer is the best means to minimise disease-related mortality. Current screening techniques have limited sensitivity and specificity. Breast nipple aspirate fluid can be obtained noninvasively and contains proteins secreted from ductal and lobular epithelia. Nipple aspirate fluid proteins are breast specific and generally more concentrated than corresponding blood levels. Proteomic analysis of 1 microl of diluted nipple aspirate fluid over a 5-40 kDa range from 20 subjects with breast cancer and 13 with nondiseased breasts identified five differentially expressed proteins. The most sensitive and specific proteins were 6500 and 15 940 Da, found in 75-84% of samples from women with cancer but in only 0-9% of samples from normal women. These findings suggest that (1) differential expression of nipple aspirate fluid proteins exists between women with normal and diseased breasts, and (2) analysis of these proteins may predict the presence of breast cancer

Measurements of high-energy neutron-induced fission of (nat)Pb and (209)Bi

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial License 3.0, which permits unrestricted use, distribution, and reproduction in any noncommercial medium, provided the original work is properly citedThe CERN Neutron Time-Of-Flight (n_TOF) facility is well suited to measure low cross sections as those of neutron-induced fission in subactinides. The cross section ratios of (nat)Pb and (209)Bi relative to (235)U and (238)U were measured using PPAC detectors and a fragment coincidence method that allows us to identify the fission events. The present experiment provides first results for neutron-induced fission up to 1 GeV. Good agreement is found with previous experimental data below 200 MeV. The comparison with proton-induced fission indicates that the limiting regime where neutron-induced and proton-induced fission reach equal cross sections is close to 1 GeV

Recoil Proton Telescopes and Parallel Plate Avalanche Counters for the 235^{235}U(n,f) cross section measurement relative to H(n,n)H between 10 and 450 MeV neutron energy

With the aim of measuring the $^{235}$U(n,f) cross section at the n\_TOF facility at CERN over a wide neutron energy range, a detection system consisting of two fission detectors and three detectors for neutron flux determination was realized. The neutron flux detectors are Recoil Proton Telescopes (RPT), based on scintillators and solid state detectors, conceived to detect recoil protons from the neutron-proton elastic scattering reaction. This system, along with a fission chamber and an array of parallel plate avalanche counters for fission event detection, was installed for the measurement at the n\_TOF facility in 2018, at CERN. An overview of the performances of two RPTs - especially developed for this measurement - and of the parallel plate avalanche counters are described in this article. In particular, the characterization in terms of detection efficiency by Monte Carlo simulations and response to neutron beam, the study of the background, dead time correction and characterization of the samples, are reported. The results of the present investigation show that the performances of these detectors are suitable for accurate measurements of fission reaction cross sections in the range from 10 to 450~MeV