A influência do jazz no repertório da guitarra clássica: contributos para a versatilidade e responsabilidade de um repertório

A razão deste projeto artístico pretende ser um contributo para a expansão do repertório com influência do jazz para guitarra clássica, com a concretização de duas obras novas. A partir da recolha do repertório já existente, o presente trabalho debruça-se igualmente na autenticidade e versatilidade a ter em conta para a execução de um repertório desta natureza, tentando, simultaneamente, entender os pontos de fusão entre a música erudita e jazz através da guitarra clássica.The aim of this artistic project is to contribute to the expansion of the jazz influenced repertoire for classical guitar, with two new works commissioned. Departing from the collected information regarding the works of this repertoire that already exist, this project also focus on the authenticity and versatility needed for the execution of this type of repertoire, trying at the same time to understand the fusion points between the classical music and jazz through the classical guitar

Cryptococcus gattii in North American Pacific Northwest: whole-population genome analysis provides insights into species evolution and dispersal

The emergence of distinct populations of Cryptococcus gattii in the temperate North American Pacific Northwest (PNW) was surprising, as this species was previously thought to be confined to tropical and semitropical regions. Beyond a new habitat niche, the dominant emergent population displayed increased virulence and caused primary pulmonary disease, as opposed to the predominantly neurologic disease seen previously elsewhere. Whole-genome sequencing was performed on 118 C. gattii isolates, including the PNW subtypes and the global diversity of molecular type VGII, to better ascertain the natural source and genomic adaptations leading to the emergence of infection in the PNW. Overall, the VGII population was highly diverse, demonstrating large numbers of mutational and recombinational events; however, the three dominant subtypes from the PNW were of low diversity and were completely clonal. Although strains of VGII were found on at least five continents, all genetic subpopulations were represented or were most closely related to strains from South America. The phylogenetic data are consistent with multiple dispersal events from South America to North America and elsewhere. Numerous gene content differences were identified between the emergent clones and other VGII lineages, including genes potentially related to habitat adaptation, virulence, and pathology. Evidence was also found for possible gene introgression from Cryptococcus neoformans var. grubii that is rarely seen in global C. gattii but that was present in all PNW populations. These findings provide greater understanding of C. gattii evolution in North America and support extensive evolution in, and dispersal from, South America. Importance: Cryptococcus gattii emerged in the temperate North American Pacific Northwest (PNW) in the late 1990s. Beyond a new environmental niche, these emergent populations displayed increased virulence and resulted in a different pattern of clinical disease. In particular, severe pulmonary infections predominated in contrast to presentation with neurologic disease as seen previously elsewhere. We employed population-level whole-genome sequencing and analysis to explore the genetic relationships and gene content of the PNW C. gattii populations. We provide evidence that the PNW strains originated from South America and identified numerous genes potentially related to habitat adaptation, virulence expression, and clinical presentation. Characterization of these genetic features may lead to improved diagnostics and therapies for such fungal infections. The data indicate that there were multiple recent introductions of C. gattii into the PNW. Public health vigilance is warranted for emergence in regions where C. gattii is not thought to be endemic

Viabilidade e autenticação molecular de cepas de Coccidioides immitis da Coleção de Culturas do Instituto Oswaldo Cruz, Rio de Janeiro, Brasil

Submitted by Sandra Infurna ([email protected]) on 2020-01-01T17:03:11Z No. of bitstreams: 1 CintiaMBorb_RenataLima_etal_IOC_2006.pdf: 64670 bytes, checksum: c4e224253c7c9e58fc68ed34581344af (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2020-01-01T17:17:53Z (GMT) No. of bitstreams: 1 CintiaMBorb_RenataLima_etal_IOC_2006.pdf: 64670 bytes, checksum: c4e224253c7c9e58fc68ed34581344af (MD5)Made available in DSpace on 2020-01-01T17:17:53Z (GMT). No. of bitstreams: 1 CintiaMBorb_RenataLima_etal_IOC_2006.pdf: 64670 bytes, checksum: c4e224253c7c9e58fc68ed34581344af (MD5) Previous issue date: 2013Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Servico de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Servico de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Servico de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micologia. Rio de Janeiro, RJ, Brasil.Vinte cepas de Coccidioides immitis foram avaliadas. Cinco das 20 cepas preservadas sob óleo mineral mantiveram-se viáveis, todas as 5 subculturas preservadas em água permaneceram viáveis e nenhuma das 13 subculturas mantidas em solo foi viável. Um produto de PCR de 519 pb do gene csa confirmou a identidade das cepas.Twenty Coccidioides immitis strains were evaluated. Only 5 of the 20 strains kept under mineral oil maintained their viability while all 5 subcultures preserved in water remained viable and none of the 13 subcultures kept in soil were viable. A 519 bp PCR product from the csa gene confirmed the identity of the strains

Corrigendum: Candida glabrata: emerging pathogen of candiduria in hospitalized patients with heart disorders

Within the 2018 ISHAM abstract supplement, the title of the abstract PP2.133 was formerly “Antifungal activity of scorpions' venom-derived antimicrobial peptides against clinical isolates of Cryptococcus neoformans.” This was incorrect and the title has since been changed to “Candida glabrata: Emerging pathogen of candiduria in hospitalized patients with heart disorders.”Submitted by Janaína Nascimento ([email protected]) on 2019-05-07T13:23:43Z No. of bitstreams: 1 ve_Guilhelmelli_F_etal_INI_2019.pdf: 267690 bytes, checksum: bf78f4815da4b9e46d943b15038ebbd5 (MD5)Approved for entry into archive by Janaína Nascimento ([email protected]) on 2019-05-07T13:34:32Z (GMT) No. of bitstreams: 1 ve_Guilhelmelli_F_etal_INI_2019.pdf: 267690 bytes, checksum: bf78f4815da4b9e46d943b15038ebbd5 (MD5)Made available in DSpace on 2019-05-07T13:34:32Z (GMT). No. of bitstreams: 1 ve_Guilhelmelli_F_etal_INI_2019.pdf: 267690 bytes, checksum: bf78f4815da4b9e46d943b15038ebbd5 (MD5) Previous issue date: 2019University of Brasília. Institute of Biological Sciences. Brasília, DF, Brazil.University of Brasília. Institute of Biological Sciences. Brasília, DF, Brazil.University of Brasília. Institute of Biological Sciences. Brasília, DF, Brazil.University of Brasília. Institute of Biological Sciences. Brasília, DF, Brazil.Fundação Oswaldo Cruz. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.University of Brasília. Faculty of Medicine. Brasília, DF, Brazil,University of Brasília. Faculty of Ceilandia. Brasília, DF, Brazil,University of Brasília. Institute of Biological Sciences. Brasília, DF, Brazil