5,174 research outputs found
Reports of recovered memories of abuse in therapy in a large age-representative U.S. national sample:therapy type and decade comparisons
The potential hazards of endeavoring to recover ostensibly repressed memories of abuse in therapy have previously been documented. Yet no large survey of the general public about memory recovery in therapy has been conducted. In an age-representative sample of 2,326 adults in the United States, we found that 9% (8% weighted to be representative) of the total sample reported seeing therapists who discussed the possibility of repressed abuse, and 5% (4% weighted) reported recovering memories of abuse in therapy for which they had no previous memory. Participants who reported therapists discussing the possibility of repressed memories of abuse were 20 times more likely to report recovered abuse memories than those who did not. Recovered memories of abuse were associated with most therapy types, and most associated with those who reported starting therapy in the 1990s. We discuss possible problems with such purported memory recovery and make recommendations for clinical training
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Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration.
Integrins coordinate spatial signaling events essential for cell polarity and directed migration. Such signals from alpha4 integrins regulate cell migration in development and in leukocyte trafficking. Here, we report that efficient alpha4-mediated migration requires spatial control of alpha4 phosphorylation by protein kinase A, and hence localized inhibition of binding of the signaling adaptor, paxillin, to the integrin. In migrating cells, phosphorylated alpha4 accumulated along the leading edge. Blocking alpha4 phosphorylation by mutagenesis or by inhibition of protein kinase A drastically reduced alpha4-dependent migration and lamellipodial stability. alpha4 phosphorylation blocks paxillin binding in vitro; we now find that paxillin and phospho-alpha4 were in distinct clusters at the leading edge of migrating cells, whereas unphosphorylated alpha4 and paxillin colocalized along the lateral edges of those cells. Furthermore, enforced paxillin association with alpha4 inhibits migration and reduced lamellipodial stability. These results show that topographically specific integrin phosphorylation can control cell migration and polarization by spatial segregation of adaptor protein binding
Distributional and Efficiency Impacts of Gasoline Taxes: An Econometrically Based Multi-market Study.
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Distributional and efficiency impacts of gasoline taxes.
This article examines the gasoline tax option being proposed in the U.S. in 2005, employing an econometrically based multi-market simulation model to explore the policy's efficiency and distributional implications. Because of its potential to improve the environment and enhance national security, reducing automobile-related gasoline consumption has become a major U.S. public policy issue. Policy impacts both in the aggregate and across households distinguished by income, car-ownership, and other characteristics were examined. Simulation results show that whether a gas-tax increase is regressive in its impact depends on the manner in which the tax revenues are recycled to the economy. The results also reveal significant heterogeneity in welfare impacts within household income groups, thus highlighting the importance of accounting for household heterogeneity in tastes and car-ownership in evaluating distributional impacts.
Laser anemometry: A status report
A laser anemometer system is being developed for the warm turbine facility as part of the HOST program. The system will be built using results obtained from the analytical and experimental research program. The status report of the laser anemometry applications research effort is presented. The designs for the turbine casing, the windows, and the positioning system were completed. A block diagram of the laser anemometer system, signal processing scheme, and computer system is given
A Music Concert with Kimberly Wright and Mark H. Lawrence: A Guest Artist Performance
This is the program for the guest artist performance of Kimberly Wright, on the horn, and Mark H. Lawrence, on the trombone. The guest artists were accompanied by Dr. Russell Hodges on piano. The concert was held on April 8, 1994, in the Recital Hall of the Mabee Fine Arts Center
Evolution of Fermion Pairing from Three to Two Dimensions
We follow the evolution of fermion pairing in the dimensional crossover from
3D to 2D as a strongly interacting Fermi gas of Li atoms becomes confined
to a stack of two-dimensional layers formed by a one-dimensional optical
lattice. Decreasing the dimensionality leads to the opening of a gap in
radio-frequency spectra, even on the BCS-side of a Feshbach resonance. The
measured binding energy of fermion pairs closely follows the theoretical
two-body binding energy and, in the 2D limit, the zero-temperature mean-field
BEC-BCS theory.Comment: 5 pages, 4 figure
Motion of a Solitonic Vortex in the BEC-BCS Crossover
We observe a long-lived solitary wave in a superfluid Fermi gas of Li
atoms after phase-imprinting. Tomographic imaging reveals the excitation to be
a solitonic vortex, oriented transverse to the long axis of the cigar-shaped
atom cloud. The precessional motion of the vortex is directly observed, and its
period is measured as a function of the chemical potential in the BEC-BCS
crossover. The long period and the correspondingly large ratio of the inertial
to the bare mass of the vortex are in good agreement with estimates based on
superfluid hydrodynamics that we derive here using the known equation of state
in the BEC-BCS crossover
Superefficiency in Nonparametric Function Estimation
Fixed parameter asymptotic statements are often used in the context of nonparametric curve estimation problems (e.g., nonparametric density or regression estimation). In this context several forms of superefficiency can occur. In contrast to what can happen in regular parametric problems, here every parameter point (e.g., unknown density or regression function) can be a point of superefficiency.
We begin with an example which shows how fixed parameter asymptotic statements have often appeared in the study of adaptive kernel estimators, and how superefficiency can occur in this context. We then carry out a more systematic study of such fixed parameter statements. It is shown in four general settings how the degree of superefficiency attainable depends on the structural assumptions in each case
Unintended Consequences From Nested State and Federal Regulations: The Case of the Pavley Greenhouse-gas-per-mile Limits
This paper reveals significant unintended consequences from recent 14-state efforts to reduce greenhouse gas emissions through limits on greenhouse gases per mile from new cars. We show that while such efforts significantly reduce emissions from new cars sold in the adopting states, they cause substantial emissions increases from new cars sold in other (non-adopting) states and from used cars. The costs per avoided ton of emissions are approximately twice as high once such offsets are recognized. Such offsets (or “leakage”) reflect interactions between the state-level initiatives and the federal fuel-economy standard: the state-level efforts effectively loosen the national standard, giving automakers scope to profitably increase sales of high-emissions automobiles in non-adopting states. Although the state-level efforts spur invention of fuel- and emissions-saving technologies, interactions with the federal standard limit the nationwide emissions reductions from such advances. Our multi-period simulation model estimates that a recent state-federal agreement avoids what would have been 74% leakage in the first phase of the state-level effort, and that potential for 65% leakage remains for the second phase. This research confronts a general issue of policy significance—namely, problems from “nested” state and federal environmental regulations. Similar leakage difficulties would arise under several newly proposed state-level initiatives
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