764 research outputs found
The kinematics of ionized gas in lyman-break analogs at z ~ 0.2
We present results for 19 âLyman-break analogsâ observed with Keck/OSIRIS with an adaptive-optics-assisted
spatial resolution of less than 200 pc. We detect satellites/companions, diffuse emission, and velocity shear, all
with high signal-to-noise ratios. These galaxies present remarkably high velocity dispersion along the line of sight
(~70 km s^(â1)), much higher than standard star-forming spirals in the low-redshift universe. We artificially redshift
our data to z ~ 2.2 to allow for a direct comparison with observations of high-z Lyman-break galaxies and find
striking similarities between both samples. This suggests that either similar physical processes are responsible
for their observed properties, or, alternatively, that it is very difficult to distinguish between different mechanisms
operating in the low- versus high-redshift starburst galaxies based on the available data. The comparison between
morphologies in the UV/optical continuum and our kinemetry analysis often shows that neither is by itself sufficient
to confirm or completely rule out the contribution from recent merger events. We find a correlation between the
kinematic properties and stellar mass, in that more massive galaxies show stronger evidence for a disk-like structure.
This suggests a co-evolutionary process between the stellar mass buildup and the formation of morphological and
dynamical substructure within the galaxy
The FIRST-Optical-VLA Survey for Lensed Radio Lobes
We present results from a survey for gravitationally lensed radio lobes.
Lensed lobes are a potentially richer source of information about galaxy mass
distributions than lensed point sources, which have been the exclusive focus of
other recent surveys. Our approach is to identify radio lobes in the FIRST
catalog and then search optical catalogs for coincident foreground galaxies,
which are candidate lensing galaxies. We then obtain higher-resolution images
of these targets at both optical and radio wavelengths, and obtain optical
spectra for the most promising candidates. We present maps of several radio
lobes that are nearly coincident with galaxies. We have not found any new and
unambiguous cases of gravitational lensing. One radio lobe in particular, FOV
J0743+1553, has two hot spots that could be multiple images produced by a
z=0.19 spiral galaxy, but the lensing interpretation is problematic.Comment: 38 pages, 18 figures, aastex, accepted to A
Retention of immobile Se(0) in flow-through aquifer column systems during bioreduction and oxic-remobilization
Selenium (Se) is a toxic contaminant with multiple anthropogenic sources, including Se-79 from nuclear fission. Se mobility in the geosphere is generally governed by its oxidation state, therefore understanding Se speciation under variable redox conditions is important for the safe management of Se contaminated sites. Here, we investigate Se behavior in sediment groundwater column systems. Experiments were conducted with environmentally relevant Se concentrations, using a range of groundwater compositions, and the impact of electron-donor (i.e., biostimulation) and groundwater sulfate addition was examined over a period of 170 days. X-Ray Absorption Spectroscopy and standard geochemical techniques were used to track changes in sediment associated Se concentration and speciation. Electron-donor amended systems with and without added sulfate retained up to 90% of added Se(VI)(aq), with sediment associated Se speciation dominated by trigonal Se(0) and possibly trace Se(-II); no Se colloid formation was observed. The remobilization potential of the sediment associated Se species was then tested in reoxidation and seawater intrusion perturbation experiments. In all treatments, sediment associated Se (i.e., trigonal Se(0)) was largely resistant to remobilization over the timescale of the experiments (170 days). However, in the perturbation experiments, less Se was remobilized from sulfidic sediments, suggesting that previous sulfate-reducing conditions may buffer Se against remobilization and migration.Peer reviewe
An Early and Comprehensive Millimetre and Centimetre Wave and X-ray Study of SN 2011dh: a Non-Equipartition Blast Wave Expanding into a Massive Stellar Wind
Only a handful of supernovae (SNe) have been studied in multiwavelengths from the radio to X-rays, starting a few days after the explosion. The early detection and classification of the nearby Type IIb SN 2011dh/PTF 11eon in M51 provides a unique opportunity to conduct such observations. We present detailed data obtained at one of the youngest phase ever of a core-collapse SN (days 3â12 after the explosion) in the radio, millimetre and X-rays; when combined with optical data, this allows us to explore the early evolution of the SN blast wave and its surroundings. Our analysis shows that the expanding SN shock wave does not exhibit equipartition (Ï”e/Ï”B ⌠1000), and is expanding into circumstellar material that is consistent with a density profile falling like Râ2. Within modelling uncertainties we find an average velocity of the fast parts of the ejecta of 15â000 ± 1800âkmâsâ1, contrary to previous analysis. This velocity places SN 2011dh in an intermediate blast wave regime between the previously defined compact and extended SN Type IIb subtypes. Our results highlight the importance of early (âŒ1âd) high-frequency observations of future events. Moreover, we show the importance of combined radio/X-ray observations for determining the microphysics ratio Ï”e/Ï”B
Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving
The nature of certain clinical samples (tissue biopsies, fluids) or the subjects themselves (pediatric subjects, neonates) often constrain the number of cells available to evaluate the breadth of functional T-cell responses to infections or therapeutic interventions. The methods most commonly used to assess this functional diversity ex vivo and to recover specific cells to expand in vitro usually require more than 106 cells. Here we present a process to identify antigen-specific responses efficiently ex vivo from 104â105 single cells from blood or mucosal tissues using dense arrays of subnanoliter wells. The approach combines on-chip imaging cytometry with a technique for capturing secreted proteinsâcalled âmicroengravingââto enumerate antigenspecific responses by single T cells in a manner comparable to conventional assays such as ELISpot and intracellular cytokine staining. Unlike those assays, however, the individual cells identified can be recovered readily by micromanipulation for further characterization in vitro. Applying this method to assess HIV-specific T cell responses demonstrates that it is possible to establish clonal CD8+ T-cell lines that represent the most abundant specificities present in circulation using 100- to 1,000-fold fewer cells than traditional approaches require and without extensive genotypic analysis a priori. This rapid (<24 h), efficient, and inexpensive process should improve the comparative study of human T-cell immunology across ages and anatomic compartments
A diagnostic autoantibody signature for primary cutaneous melanoma
Melanoma is an aggressive form of skin cancer that is curable by surgical excision in the majority of cases, if detected at an early stage. To improve early stage melanoma detection, the development of a highly sensitive diagnostic test is of utmost importance. Here we aimed to identify antibodies to a panel of tumour associated antigens that can differentiate primary melanoma patients and healthy individuals. A total of 245 sera from primary melanoma patients and healthy volunteers were screened against a high-throughput microarray platform containing 1627 functional proteins. Following rigorous statistical analysis, we identified a combination of 10 autoantibody biomarkers that, as a panel, displays a sensitivity of 79%, specificity of 84% and an AUC of 0.828 for primary melanoma detection. This melanoma autoantibody signature may prove valuable for the development of a diagnostic blood test for routine population screening that, when used in conjunction with current melanoma diagnostic techniques, could improve the early diagnosis of this malignancy and ultimately decrease the mortality rate of patients
Language and social/emotional problems identified at a universal developmental assessment at 30 months
Non peer reviewedPublisher PD
An Early & Comprehensive Millimeter and Centimeter Wave and X-ray Study of Supernova 2011dh: A Non-Equipartition Blastwave Expanding into A Massive Stellar Wind
Only a handful of supernovae (SNe) have been studied in multi-wavelength from
radio to X-rays, starting a few days after explosion. The early detection and
classification of the nearby type IIb SN2011dh/PTF11eon in M51 provides a
unique opportunity to conduct such observations. We present detailed data
obtained at the youngest phase ever of a core-collapse supernova (days 3 to 12
after explosion) in the radio, millimeter and X-rays; when combined with
optical data, this allows us to explore the early evolution of the SN blast
wave and its surroundings. Our analysis shows that the expanding supernova
shockwave does not exhibit equipartition (e_e/e_B ~ 1000), and is expanding
into circumstellar material that is consistent with a density profile falling
like R^-2. Within modeling uncertainties we find an average velocity of the
fast parts of the ejecta of 15,000 +/- 1800 km/s, contrary to previous
analysis. This velocity places SN 2011dh in an intermediate blast-wave regime
between the previously defined compact and extended SN IIb subtypes. Our
results highlight the importance of early (~ 1 day) high-frequency observations
of future events. Moreover, we show the importance of combined radio/X-ray
observations for determining the microphysics ratio e_e/e_B.Comment: 9 pages, 5 figures, submitted to Ap
Evidence for an FU Orionis-like Outburst from a Classical T Tauri Star
We present pre- and post-outburst observations of the new FU Orionis-like
young stellar object PTF 10qpf (also known as LkHa 188-G4 and HBC 722). Prior
to this outburst, LkHa 188-G4 was classified as a classical T Tauri star on the
basis of its optical emission-line spectrum superposed on a K8-type
photosphere, and its photometric variability. The mid-infrared spectral index
of LkHa 188-G4 indicates a Class II-type object. LkHa 188-G4 exhibited a steady
rise by ~1 mag over ~11 months starting in Aug. 2009, before a subsequent more
abrupt rise of > 3 mag on a time scale of ~2 months. Observations taken during
the eruption exhibit the defining characteristics of FU Orionis variables: (i)
an increase in brightness by > 4 mag, (ii) a bright optical/near-infrared
reflection nebula appeared, (iii) optical spectra are consistent with a G
supergiant and dominated by absorption lines, the only exception being Halpha
which is characterized by a P Cygni profile, (iv) near-infrared spectra
resemble those of late K--M giants/supergiants with enhanced absorption seen in
the molecular bands of CO and H_2O, and (v) outflow signatures in H and He are
seen in the form of blueshifted absorption profiles. LkHa 188-G4 is the first
member of the FU Orionis-like class with a well-sampled optical to mid-infrared
spectral energy distribution in the pre-outburst phase. The association of the
PTF 10qpf outburst with the previously identified classical T Tauri star LkHa
188-G4 (HBC 722) provides strong evidence that FU Orionis-like eruptions
represent periods of enhanced disk accretion and outflow, likely triggered by
instabilities in the disk. The early identification of PTF 10qpf as an FU
Orionis-like variable will enable detailed photometric and spectroscopic
observations during its post-outburst evolution for comparison with other known
outbursting objects.Comment: 14 pages, 11 figures, ApJ accepte
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