2,512 research outputs found
A curvilinear snake arm robot with gripper-axis fibre-optic image processor feedback
The official version of this article can be found at the link below.A curvilinear robot constructed from a number of modular flexible sections of fixed length and diameter but independently controlled radius and direction of curvature has been equipped with an optical fibre image guide transmitting images from between the gripper jaws to the remote TV camera of Microvision-100, a microcomputer controlled real-time DMA-based vision System that is easily trained to recognise the shape, position and orientation of components. The gripper position and orientation is controlled by feedback from the vision System, the action taken depending on component recognition and inspection for defects. Redundant degrees of freedom enable the curvilinear robot to avoid obstacles and work in confined spaces.The research programme described in this paper is supported by the U.K. Science and Engineering Research Council
Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin.
ChineseâSpanish neural machine translation enhanced with character and word bitmap fonts
Recently, machine translation systems based on neural networks have reached state-of-the-art results for some pairs of languages (e.g., GermanâEnglish). In this paper, we are investigating the performance of neural machine translation in ChineseâSpanish, which is a challenging language pair. Given that the meaning of a Chinese word can be related to its graphical representation, this work aims to enhance neural machine translation by using as input a combination of: words or characters and their corresponding bitmap fonts. The fact of performing the interpretation of every word or character as a bitmap font generates more informed vectorial representations. Best results are obtained when using words plus their bitmap fonts obtaining an improvement (over a competitive neural MT baseline system) of almost six BLEU, five METEOR points and ranked coherently better in the human evaluation.Peer ReviewedPostprint (published version
Niacin-induced clotting factor synthesis deficiency with coagulopathy
Although coagulopathy is a well-known complication of severe niacin- induced hepatotoxic reaction, it is not found in patients with minimal aminotransferase level elevations. Three patients with significant clotting factor synthesis deficiency and coagulopathy (prothrombin times, >1.5 times control) from sustained-release niacin had only mild aminotransferase level elevations (1.5 to 2.0 times normal). In each case, protein deficiency, coagulopathy, and aminotransferase level elevation resolved promptly after withdrawal of niacin therapy. In one case, this syndrome recurred after rechallenge with sustained-release niacin, whereas the coagulopathy did not recur in a second patient rechallenged with crystalline niacin. Deficiency in protein synthesis, including coagulation factors, and coagulopathy are unrecognized complications of sustained-release niacin therapy. These cases indicate the need to measure prothrombin times routinely in patients who develop even mild aminotransferase level elevation while receiving sustained- release niacin therapy. These data are important in light of the increasing use of sustained-release niacin in the treatment of patients with lipid disorders
High-energy environment of super-Earth 55 Cnc e I: Far-UV chromospheric variability as a possible tracer of planet-induced coronal rain
The irradiation of close-in planets by their star influences their evolution
and might be responsible for a population of ultra-short period planets eroded
to their bare core. In orbit around a bright, nearby G-type star, the
super-Earth 55 Cnc e offers the possibility to address these issues through UV
transit observations. We used the Hubble Space Telescope to observe the transit
in the FUV over 3 epochs in Apr. 2016, Jan. 2017, and Feb. 2017. These
observations reveal significant short- and long-term variability in 55 Cnc
chromospheric emission lines. In the last 2 epochs, we detected a larger flux
in the C III, Si III, and Si IV lines after the planet passed the approaching
quadrature, followed by a flux decrease in the Si IV doublet. In the second
epoch these variations are contemporaneous with flux decreases in the Si II and
C II doublet. All epochs show flux decreases in the N V doublet as well, albeit
at different orbital phases. These flux decreases are consistent with
absorption from optically thin clouds of gas, are mostly localized at low and
redshifted radial velocities in the star rest frame, and occur preferentially
before and during the transit. These 3 points make it unlikely that the
variations are purely stellar, yet we show that the occulting material is also
unlikely to originate from the planet. We tentatively propose that the motion
of 55 Cnc e at the fringes of the stellar corona leads to the formation of a
cool coronal rain. The inhomogeneity and temporal evolution of the stellar
corona would be responsible for the differences between the visits. Additional
variations are detected in the C II doublet in the first epoch and in the O I
triplet in all epochs with a different behavior that points toward intrinsic
stellar variability. Further observations at FUV wavelengths are required to
disentangle between star-planet interactions and the activity of the starComment: 22 pages, 20 figures, accepted for publication in A&
Neural correlates of attentional capture in visual search
Much behavioral research has shown that the presence of a unique singleton distractor during a task of visual search will typically capture attention and thus disrupt search. Here we examined the neural correlates of such attentional capture using functional magnetic resonance imaging in human divisions during performance of a visual search task. The presence (vs. absence) of a salient yet irrelevant color singleton distractor was associated with activity in the superior parietal cortex and frontal cortex. These findings imply that the singleton distractor induced spatial shifts of attention despite its irrelevance, as predicted from an AC account. Moreover, behavioral interference by singleton distractors was strongly and negatively correlated with frontal activity. These findings provode direct evidence that the frontal cortex is involved in control of interference from irrelevant but attention-capturing distractors
The role of working memory in visual selective attention
The hypothesis is that working memory is crucial for reducing distraction by maintaining the prioritization of relevant information was tested in neuroimaging and psychological experiments with humans. Participants performed a selective attention task that required them to ignore distractor faces while holding in working memory a sequence of digits that were in the same order (low memory load) or a different order (high memory load) on every trial. Higher memory load, associated with increased prefrontal activity, resulted in greater interference effects on behavioral performance from the distractor faces, plus increased face-related activity in the visual cortex. These findings confirm a major role for working memory in the control of visual selective attention
Load-induced inattentional deafness.
High perceptual load in a task is known to reduce the visual perception of unattended items (e.g., Lavie, Beck, & Konstantinou, 2014). However, it remains an open question whether perceptual load in one modality (e.g., vision) can affect the detection of stimuli in another modality (e.g., hearing). We report four experiments that establish that high visual perceptual load leads to reduced detection sensitivity in hearing. Participants were requested to detect a tone that was presented during performance of a visual search task of either low or high perceptual load (varied through item similarity). The findings revealed that auditory detection sensitivity was consistently reduced with higher load, and that this effect persisted even when the auditory detection response was made first (before the search response) and when the auditory stimulus was highly expected (50Â % present). These findings demonstrate a phenomenon of load-induced deafness and provide evidence for shared attentional capacity across vision and hearing
Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure
The long egress of GJ~436b's giant exosphere
The M dwarf GJ 436 hosts a transiting warm Neptune known to experience
atmospheric escape. Previous observations revealed the presence of a giant
hydrogen exosphere transiting the star for more than 5 h, and absorbing up to
56% of the flux in the blue wing of the stellar Lyman-{\alpha} line of neutral
hydrogen (H i Ly{\alpha}). The unexpected size of this comet-like exosphere
prevented observing the full transit of its tail. In this Letter, we present
new Ly{\alpha} observations of GJ 436 obtained with the Space Telescope Imaging
Spectrograph (STIS) instrument onboard the Hubble Space Telescope. The
stability of the Ly{\alpha} line over six years allowed us to combine these new
observations with archival data sets, substantially expanding the coverage of
the exospheric transit. Hydrogen atoms in the tail of the exospheric cloud keep
occulting the star for 10-25 h after the transit of the planet, remarkably
confirming a previous prediction based on 3D numerical simulations with the
EVaporating Exoplanet code (EVE). This result strengthens the interpretation
that the exosphere of GJ 436b is shaped by both radiative braking and charge
exchanges with the stellar wind. We further report flux decreases of 15 +/- 2%
and 47 +/- 10% in the red wing of the Ly{\alpha} line and in the line of
ionised silicon (Si iii). Despite some temporal variability possibly linked
with stellar activity, these two signals occur during the exospheric transit
and could be of planetary origin. Follow-up observations will be required to
assess the possibility that the redshifted Ly{\alpha} and Si iii absorption
signatures arise from interactions between the exospheric flow and the magnetic
field of the star.Comment: 10 pages, 7 figures, published in A&
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