56 research outputs found

    Deciphering the molecular adaptation of the king scallop (Pecten maximus) to heat stress using transcriptomics and proteomics

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    Background The capacity of marine species to survive chronic heat stress underpins their ability to survive warming oceans as a result of climate change. In this study RNA-Seq and 2-DE proteomics were employed to decipher the molecular response of the sub-tidal bivalve Pecten maximus, to elevated temperatures. Results Individuals were maintained at three different temperatures (15, 21 and 25 °C) for 56 days, representing control conditions, maximum environmental temperature and extreme warming, with individuals sampled at seven time points. The scallops thrived at 21 °C, but suffered a reduction in condition at 25 °C. RNA-Seq analyses produced 26,064 assembled contigs, of which 531 were differentially expressed, with putative annotation assigned to 177 transcripts. The proteomic approach identified 24 differentially expressed proteins, with nine identified by mass spectrometry. Network analysis of these results indicated a pivotal role for GAPDH and AP-1 signalling pathways. Data also suggested a remodelling of the cell structure, as revealed by the differential expression of genes involved in the cytoskeleton and cell membrane and a reduction in DNA repair. They also indicated the diversion of energetic metabolism towards the mobilization of lipid energy reserves to fuel the increased metabolic rate at the higher temperature. Conclusions This work provides preliminary insights into the response of P. maximus to chronic heat stress and provides a basis for future studies examining the tipping points and energetic trade-offs of scallop culture in warming oceans

    La rétinopathie hypertensive chez le chat

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    peer reviewedLa rétinopathie hypertensive est fréquente chez le chat âgé atteint d’hypertension artérielle. Les principales lésions oculaires sont des hémorragies rétiniennes et/ou des décollements de rétine pouvant conduire à une cécité parfois brutale. Les démarches diagnostiques et thérapeutiques doivent être rigoureuses afin de stabiliser rapidement les lésions, la restauration de la vision restant possible, mais exceptionnelle. Le traitement antihypertenseur est souvent mis en place en urgence et la prévention de l’apparition d’une hypertension artérielle reste le meilleur moyen d’éviter cette situation

    Réseau SEAVIEW

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    PRODUITS ET OUTILS INFORMATIQUES / Publications informatiques - Site web du réseau SEAVIEW https://seaview.u-bordeaux.fr à la suite d'un contrat de recherche Belmont Forum sur les scenarios de biodiversit

    RMA Newsletter - Fall 2019

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    PRODUITS DESTINÉS AU GRAND PUBLIC / Produits de vulgarisation : articles, interview
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