2,004 research outputs found

    Designs of Langmuir Probes for W7-X

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    Strategies to effectively promote and market on-farm retail enterprises

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    Agritourism offers consumers the opportunity to purchase locally grown food on the farm along with the educational experience of learning about food production. This project was designed to help energize Iowa\u27s agritourism industry

    Energy Star: A Competitive Advantage?

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    Voluntary government programs such as ENERGY STAR have been created to promote energy efficiency within different organizations and businesses, and this study is dedicated to discovering whether or not businesses that become certified building partners with ENERGY STAR obtain a competitive advantage. Through two different methods of analysis, an observational analysis and a test of means, data on profitability ratios from twenty-five ENERGY STAR partners are examined to determine if partnering with ENERGY STAR results in a competitive advantage

    Stochastic bias correction of dynamically downscaled precipitation fields for Germany through copula-based integration of gridded observation data

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    Dynamically downscaled precipitation fields from regional climate models (RCMs) often cannot be used directly for regional climate studies. Due to their inherent biases, i.e., systematic over- or underestimations compared to observations, several correction approaches have been developed. Most of the bias correction procedures such as the quantile mapping approach employ a transfer function that is based on the statistical differences between RCM output and observations. Apart from such transfer function-based statistical correction algorithms, a stochastic bias correction technique, based on the concept of Copula theory, is developed here and applied to correct precipitation fields from the Weather Research and Forecasting (WRF) model. For dynamically downscaled precipitation fields we used high-resolution (7 km, daily) WRF simulations for Germany driven by ERA40 reanalysis data for 1971–2000. The REGNIE (REGionalisierung der NIEderschlagshöhen) data set from the German Weather Service (DWD) is used as gridded observation data (1 km, daily) and aggregated to 7 km for this application. The 30-year time series are split into a calibration (1971–1985) and validation (1986–2000) period of equal length. Based on the estimated dependence structure (described by the Copula function) between WRF and REGNIE data and the identified respective marginal distributions in the calibration period, separately analyzed for the different seasons, conditional distribution functions are derived for each time step in the validation period. This finally allows to get additional information about the range of the statistically possible bias-corrected values. The results show that the Copula-based approach efficiently corrects most of the errors in WRF derived precipitation for all seasons. It is also found that the Copula-based correction performs better for wet bias correction than for dry bias correction. In autumn and winter, the correction introduced a small dry bias in the northwest of Germany. The average relative bias of daily mean precipitation from WRF for the validation period is reduced from 10% (wet bias) to −1% (slight dry bias) after the application of the Copula-based correction. The bias in different seasons is corrected from 32% March–April–May (MAM), −15% June–July–August (JJA), 4% September–October–November (SON) and 28% December–January–February (DJF) to 16% (MAM), −11% (JJA), −1% (SON) and −3% (DJF), respectively. Finally, the Copula-based approach is compared to the quantile mapping correction method. The root mean square error (RMSE) and the percentage of the corrected time steps that are closer to the observations are analyzed. The Copula-based correction derived from the mean of the sampled distribution reduces the RMSE significantly, while, e.g., the quantile mapping method results in an increased RMSE for some regions

    Effects of Magnetic Field on Josephson Current in SNS System

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    The effect of a magnetic field on Josephson current has been studied for a superconductor/normal-metal/superconductor (SNS) system, where N is a two-dimensional electron gas in a confining potential. It is found that the dependence of Josephson currents on the magnetic field are sensitive to the width of the normal metal. If the normal metal is wide and contains many channels (subbands), the current on a weak magnetic field shows a dependence similar to a Fraunhofer-pattern in SIS system and, as the field gets strong, it shows another type of oscillatory dependence on the field resulting from the Aharonov-Bohm interference between the edge states. As the number of channels decreases (i.e. normal metal gets narrower), however, the dependence in the region of the weak field deviates from a clear Fraunhofer pattern and the amplitude of the oscillatory dependence in the region of the strong field is reduced.Comment: 14 pages, 9 figure

    Dialysis enrollment patterns in Guatemala: Evidence of the chronic kidney disease of non-traditional causes epidemic in Mesoamerica

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    BACKGROUND: In western Nicaragua and El Salvador, chronic kidney disease (CKD) is highly prevalent and generally affects young, male, agricultural (usually sugar cane) workers without the established CKD risk factors. It is yet unknown if the prevalence of this CKD of Non-Traditional causes (CKDnT) extends to the northernmost Central American country, Guatemala. Therefore, we sought to compare dialysis enrollment rates by region, municipality, sex, daily temperature, and agricultural production in Guatemala and assess if there is a similar CKDnT distribution pattern as in Nicaragua and El Salvador. METHODS: The National Center for Chronic Kidney Disease Treatment (Unidad Nacional de Atención al Enfermo Renal Crónico) is the largest provider of dialysis in Guatemala. We used population, Human Development Index, literacy, and agricultural databases to assess the geographic, economic, and educational correlations with the National Center for Chronic Kidney Disease Treatment’s hemodialysis and peritoneal dialysis enrollment database. Enrollment rates (per 100 000) inhabitants were compared by region and mapped for comparison to regional agricultural and daytime temperature data. The distribution of men and women enrolled in dialysis were compared by region using Fisher’s exact tests. Spearman’s rank correlation coefficients were calculated. RESULTS: Dialysis enrollment is higher in the Southwest compared to the rest of the country where enrollees are more likely (p < 0.01) to be male (57.8%) compared to the rest of the country (49.3%). Dialysis enrollment positively correlates with Human Development Index and literacy rates. These correlations are weaker in the agricultural regions (predominantly sugar cane) of Southwest Guatemala. CONCLUSIONS: In Guatemala, CKDnT incidence may have a similar geographic distribution as Nicaragua and El Salvador (higher in the high temperature and sugar cane growing regions). Therefore, it is likely that the CKNnT epidemic extends throughout the Mesoamerican region

    In Vivo Colonization of the Mouse Large Intestine and In Vitro Penetration of Intestinal Mucus by an Avirulent Smooth Strain of Salmonella typhimurium and Its Lipopolysaccharide-Deficient Mutant

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    The relative abilities of an avirulent Salmonella typhimurium strain with wild-type lipopolysaccharide (LPS) character, SL5319, and a nearly isogenic LPS-deficient mutant, SL5325, to colonize the large intestines of streptomycin-treated CD-1 mice in vivo and to penetrate colonic mucus in vitro were studied. Previously it had been shown that, when fed simultaneously to streptomycin-treated mice (approximately 1010 CFU each), the S. typhimurium strain with wild-type LPS colonized at 108 CFU/g of feces indefinitely, whereas the LPS-deficient mutant dropped within 3 days to a level of only 104 CFU/g of feces. In the present investigation, when SL5325 was allowed to colonize for 8 days before feeding mice SL5319 or when it was fed to mice simultaneously with an Escherichia coli strain of human fecal origin (1010 CFU each), both strains colonized indefinitely at 107 CFU/g of feces. Moreover, when the wild-type and LPS-deficient mutant strains were fed to mice simultaneously in low numbers (approximately 105 CFU each) the strains survived equally well in the large intestines for 8 days, after which the LPS-deficient mutant was eliminated (less than 102 CFU/g of feces), whereas the wild-type colonized at a level of 107 CFU/g of feces. In addition although both strains were able to adhere to mucus and epithelial cell preparations in vitro, the wild-type strain was shown to have greater motility and chemotactic activity on CD-1 mouse colonic mucus in vitro and to more rapidly penetrate and form a stable association with immobilized colonic mucosal components in vitro. Based on these data, we suggest that the ability of an S. typhimurium strain to colonize the streptomycin-treated mouse large intestine may, in part, depend on its ability to penetrate deeply into the mucus layer on the intestinal wall and subsequently, through growth, colonize the mucosa
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