AIDS education on college campuses

Many researchers have examined the issue of college students and AIDS. Most have come to the same conclusion, that students know how to protect themselves but don\u27t see AIDS as personal threat to their lives. As colleges become more diverse and more students are able to attend college, these issues probably will become more complex. Coupled with diversity issues, AIDS has now become known as a chronic rather than deadly disease, as a result of progress made toward treating AIDS and through early detection

Gender in endocrine diseases: role of sex gonadal hormones

Gender- and sex- related differences represent a new frontier towards patient-tailored medicine, taking into account that theoretically every medical specialty can be influenced by both of them. Sex hormones define the differences between males and females, and the different endocrine environment promoted by estrogens, progesterone, testosterone, and their precursors might influence both human physiology and pathophysiology. With the term Gender we refer, instead, to behaviors, roles, expectations, and activities carried out by the individual in society. In other words, “gender” refers to a sociocultural sphere of the individual, whereas “sex” only defines the biological sex. In the last decade, increasing attention has been paid to understand the influence that gender can have on both the human physiology and pathogenesis of diseases. Even the clinical response to therapy may be influenced by sex hormones and gender, but further research is needed to investigate and clarify how they can affect the human pathophysiology. The path to a tailored medicine in which every patient is able to receive early diagnosis, risk assessments, and optimal treatments cannot exclude the importance of gender. In this review, we have focused our attention on the involvement of sex hormones and gender on different endocrine diseases

Tafassasset: The Saga Continues

In this study, we compare data for two separate Tafassasset stones and supply new oxygen isotope data for our sample. We include a discussion of the debate surrounding the classification of Tafassasset and offer a hypothesis for its origin based upon new information

Effects of Head Formation and Heat Treatment on the Mechanical Properties of Connecting Rod Bolts

Oliver Racing Parts (ORP; Charlevoix, Michigan) is looking to optimize their manufacturing process for high-strength connecting rod bolts. A high yield strength is desired for the bolts because deformation would result in catastrophic engine failure. The bolts were made of H11, a chromium hot-work tool steel; and MLX17, a precipitation hardenable stainless steel. Tensile testing was performed to determine the tensile and yield strengths of the bolts. Fracture surfaces were imaged via scanning electron microscopy to characterize the failure modes. To observe the effects of bolt heading on microstructure and bolt strength, two batches of MLX17 were prepared; one batch being headed then aged (Group A); the other batch being headed, solution annealed, and then aged (Group B). These bolts were compared to H11 bolts to determine their viability for use, with the results being in the order of highest to lowest yield strength: H11 (272 ksi), MLX17 Treatment B (250 ksi), and MLX17 Treatment A (235 ksi). In the order of highest to lowest tensile strength: H11 (300 ksi), MLX17 Group B (255 ksi), MLX17 Group A (238 ksi). It is suggested that the bolt heading process is causing some overaging in the MLX17 samples, shown by the increase in strength when strain and aging from the heading process are undone through heat treatment. H11 bolts were the strongest tested. Recommendations are to not replace H11 bolts with MLX17 due to a decrease in strength

Endocrine disrupting chemicals: Effects on endocrine glands

In recent years, endocrine disrupting chemicals have gained interest in human physiopathology and more and more studies aimed to explain how these chemicals compounds affect endocrine system. In human populations, the majority of the studies point toward an association between exposure to endocrine disrupting chemicals and the disorders affecting endocrine axis. A great number of endocrine disrupting chemicals seem to be able to interfere with the physiology of hypothalamus-pituitary-gonadal axis; however, every endocrine axis may be a target for each EDCs and their action is not limited to a single axis or organ. Several compounds may also have a negative impact on energy metabolic homeostasis altering adipose tissue and promoting obesity, metabolic syndrome, and diabetes. Different mechanism have been proposed to explain these associations but their complexity together with the degree of occupational or environmental exposure, the low standardization of the studies, and the presence of confounding factors have prevented to establish causal relationship between the endocrine disorders and exposure to specific toxicants so far. This manuscript aims to review the state of art of scientific literature regarding the effects of endocrine-disrupting chemicals (EDCs) on endocrine system

Specific and non-specific biomarkers in neuroendocrine gastroenteropancreatic tumors

The diagnosis of neuroendocrine tumors (NETs) is a challenging task: Symptoms are rarely specific, and clinical manifestations are often evident only when metastases are already present. However, several bioactive substances secreted by NETs can be included for diagnostic, prognostic, and predictive purposes. Expression of these substances differs between different NETs according to the tumor hormone production. Gastroenteropancreatic (GEP) NETs originate from the diffuse neuroendocrine system of the gastrointestinal tract and pancreatic islets cells: These tumors may produce many non-specific and specific substances, such as chromogranin A, insulin, gastrin, glucagon, and serotonin, which shape the clinical manifestations of the NETs. To provide an up-to-date reference concerning the different biomarkers, as well as their main limitations, we reviewed and summarized existing literature

Tourisme et Croissance Inclusive au Bénin: Une Analyse d’Après l’Indice Synthétique de Croissance Inclusive

Cette étude vise à examiner le type de relation entre tourisme et croissance inclusive au Bénin de 1995 à 2021 en utilisant comme variable dépendante, contrairement à plusieurs études,  l’Indice Synthétique de Croissance Inclusive  (ISCI). En nous appuyant sur des données chronologiques, nous avons effectué des estimations à l'aide du Modèle Vectoriel à Correction d'Erreur (VECM), du test de causalité de Granger et du Modèle à Correction d'Erreur (MCE) sous STATA 15. Les résultats révèlent une relation significative positive entre le ratio des recettes touristiques réelles et l'Indice Synthétique de Croissance Inclusive (ISCI), démontrant que le tourisme contribue à la croissance inclusive jusqu'à un certain seuil. En outre,  la nature bidirectionnelle de cette relation (entre tourisme et croissance inclusive) a été également mise en évidence.   This study aims to examine the type of relationship between tourism and inclusive growth in Benin from 1995 to 2021 using as a dependent variable, unlike several studies, the Synthetic Inclusive Growth Index (ISCI). Based on historical data, we carried out estimations using the Vector Error Correction Model (VECM), the Granger causality test and the Error Correction Model (ECM) under STATA 15. The results reveal a significant positive relationship between the ratio of real tourism receipts and the Synthetic Inclusive Growth Index (ISCI), demonstrating that tourism contributes to inclusive growth up to a certain threshold. Furthermore, the bidirectional nature of this relationship (between tourism and inclusive growth) was also highlighted

Tourisme et Croissance Inclusive au Bénin: Une Analyse d’Après l’Indice Synthétique de Croissance Inclusive

Cette étude vise à examiner le type de relation entre tourisme et croissance inclusive au Bénin de 1995 à 2021 en utilisant comme variable dépendante, contrairement à plusieurs études,  l’Indice Synthétique de Croissance Inclusive  (ISCI). En nous appuyant sur des données chronologiques, nous avons effectué des estimations à l'aide du Modèle Vectoriel à Correction d'Erreur (VECM), du test de causalité de Granger et du Modèle à Correction d'Erreur (MCE) sous STATA 15. Les résultats révèlent une relation significative positive entre le ratio des recettes touristiques réelles et l'Indice Synthétique de Croissance Inclusive (ISCI), démontrant que le tourisme contribue à la croissance inclusive jusqu'à un certain seuil. En outre,  la nature bidirectionnelle de cette relation (entre tourisme et croissance inclusive) a été également mise en évidence.   This study aims to examine the type of relationship between tourism and inclusive growth in Benin from 1995 to 2021 using as a dependent variable, unlike several studies, the Synthetic Inclusive Growth Index (ISCI). Based on historical data, we carried out estimations using the Vector Error Correction Model (VECM), the Granger causality test and the Error Correction Model (ECM) under STATA 15. The results reveal a significant positive relationship between the ratio of real tourism receipts and the Synthetic Inclusive Growth Index (ISCI), demonstrating that tourism contributes to inclusive growth up to a certain threshold. Furthermore, the bidirectional nature of this relationship (between tourism and inclusive growth) was also highlighted