269 research outputs found

    Jean-Léon Gérôme : un peintre d’histoire présumé « cinéaste »

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    La riche exposition consacrée par le Musée d’Orsay au peintre académique Jean-Léon Gérôme développait un discours explicite sur la relation entre ce peintre et le cinéma en des termes susceptibles d’ouvrir un débat fécond sur les manières d’envisager les liens entre le film et les arts plastiques qui l’ont précédé. L’accrochage, le catalogue, certaines interventions du colloque « Regarder Gérôme », ainsi que le « cycle péplum », présenté au Musée ont engagé, sur cette question de la référence au cinéma, de stimulantes réflexions d’ordre méthodologique et historiographique. En effet, l’accent n’a pas porté sur une contextualisation directe qui mette en perspective l’oeuvre de Gérôme par rapport aux avancées des techniques d’enregistrement de son époque, de projection et d’animation mécanique des images et qui ont conduit, dès les années 1880, à l’émergence du médium cinématographique, l’argument de l’exposition visait plutôt à dégager de l’oeuvre de Gérôme les signes d’une véritable « préfiguration » du cinéma, organisée en fonction de deux grands axes : d’une part l’influence manifeste de la peinture d’histoire sur l’iconographie des films de fiction à grand spectacle ; d’autre part, des procédés visuels plus généraux, susceptibles d’être reliés à des effets spécifiquement cinématographiques. En reprenant la question du point de vue des recherches en histoire du cinéma, cet article souhaite soulever à cette occasion quelques problèmes d’ordre méthodologique.The exhibition at the Musée d’Orsay devoted to the painter Jean-Léon Gérôme developed an explicit argument about the relationship between this painter and cinema, in such a way as to open a broader debate about how to consider the links between film and the visual arts that preceded it. The design of the exhibition, the catalogue, certain interventions at the « Regarder Gérôme » conference, and the « peplum » film season at the Museum, all have contributed to a stimulating reflection on this question of the reference to cinema, from a methodological and historiographical point of view. The emphasis was not placed on the simple contextualisation of Gérôme in relation to the technical advances of the time, in terms of recording, projection and mechanical animation, which led to the emergence of the film medium from the 1880s. The argument of the exhibition was rather focused on highlighting in Gérôme’s work signs of a genuine « prefiguration » of cinema, conceived in two principal ways: first, the evident influence of painting on the iconography of spectacular fiction feature films; secondly, more general visual techniques linked to specific filmic effects. This article aims to raise some methodological problems that emerge when discussing this matter from the viewpoint of research in film history

    : Géoprospective territoriale à l'île de La Réunion

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    16 p.National audienceThe objective of this paper is to present an approach for experimenting territorial prospective analysis based on spatial modelling. This approach is carried out in the framework of the DESCARTES project which aims at developing a spatial simulation tool to support the design and analysis of different scenarios for land-use allocation in Reunion Island in terms of environmental services. The spatial modelling tool is composed of two complementary applications: (i) the Ocelet modelling language and its land dynamics simulation environment, and (ii) the Margouill@ platform. The first demonstrator, a model of farm land consumption by urbanization, was developed and presented during workshops in order to test the role of the spatial simulation tool in support of a collaborative innovation process among stakeholders, and to foster new research on social learning, spatial simulation of environmental services, and scale change issues.L'objectif de cet article est de présenter une démarche de construction d'un exercice de prospective territoriale basé sur un outil de modélisation spatiale. Cette démarche est mise en œuvre dans le cadre du projet ANR DESCARTES dont l'objectif est de construire un outil de simulation cartographique pour analyser différents scénarios d'affectation de l'usage des sols à l'Ile de La Réunion, en termes de services environnementaux. La plateforme de simulation cartographique est composée de deux applications complémentaires (i) le langage de modélisation Ocelet et son environnement de simulation de paysages dynamiques, et (ii) la plateforme Margouill@. Le développement puis la présentation, en atelier, d'un premier démonstrateur sur la consommation des terres agricoles par l'urbanisation a permis de tester l'outil cartographique comme support d'un processus d'innovation collective entre les parties prenantes, et d'ouvrir de nouveaux champs de recherche sur l'analyse de la démarche par les apprentissages, la spatialisation et la simulation prospective des services écosystémiques, et la prise en compte du changement d'échelle

    Rainforest transformation reallocates energy from green to brown food webs.

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    Terrestrial animal biodiversity is increasingly being lost because of land-use change1,2. However, functional and energetic consequences aboveground and belowground and across trophic levels in megadiverse tropical ecosystems remain largely unknown. To fill this gap, we assessed changes in energy fluxes across 'green' aboveground (canopy arthropods and birds) and 'brown' belowground (soil arthropods and earthworms) animal food webs in tropical rainforests and plantations in Sumatra, Indonesia. Our results showed that most of the energy in rainforests is channelled to the belowground animal food web. Oil palm and rubber plantations had similar or, in the case of rubber agroforest, higher total animal energy fluxes compared to rainforest but the key energetic nodes were distinctly different: in rainforest more than 90% of the total animal energy flux was channelled by arthropods in soil and canopy, whereas in plantations more than 50% of the energy was allocated to annelids (earthworms). Land-use change led to a consistent decline in multitrophic energy flux aboveground, whereas belowground food webs responded with reduced energy flux to higher trophic levels, down to -90%, and with shifts from slow (fungal) to fast (bacterial) energy channels and from faeces production towards consumption of soil organic matter. This coincides with previously reported soil carbon stock depletion3. Here we show that well-documented animal biodiversity declines with tropical land-use change4-6 are associated with vast energetic and functional restructuring in food webs across aboveground and belowground ecosystem compartments

    Longitudinal ambulatory measurements of gait abnormality in dystrophin-deficient dogs

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    Chantier qualité GAInternational audienceABSTRACT: BACKGROUND: This study aimed to measure the gait abnormalities in GRMD (Golden retriever muscular dystrophy) dogs during growth and disease progression using an ambulatory gait analyzer (3D-accelerometers) as a possible tool to assess the effects of a therapeutic intervention. METHODS: Six healthy and twelve GRMD dogs were evaluated twice monthly, from the age of two to nine months. The evolution of each gait variable previously shown to be modified in control and dystrophin-deficient adults was assessed using two-ways variance analysis (age, clinical status) with repeated measurements. A principal component analysis (PCA) was applied to perfect multivariate data interpretation. RESULTS: Speed, stride length, total power and force significantly already decreased (p < 0.01) at the age of 2 months. The other gait variables (stride frequency, relative power distributions along the three axes) became modified at later stages. Using the PCA analysis, a global gait index taking into account the main gait variables was calculated, and was also consistent to detect the early changes in the GRMD gait patterns, as well as the progressive degradation of gait quality. CONCLUSION: The gait variables measured by the accelerometers were sensitive to early detect and follow the gait disorders and mirrored the heterogeneity of clinical presentations, giving sense to monitor gait in GRMD dogs during progression of the disease and pre-clinical therapeutic trials

    Monitoring Virologic Responses to Antiretroviral Therapy in HIV-Infected Adults in Kenya: Evaluation of a Low-Cost Viral Load Assay

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    A key advantage of monitoring HIV viral load (VL) in persons receiving antiretroviral therapy (ART) is the ability to detect virologic failure before clinical deterioration or resistance occurs. Detection of virologic failure will help clarify the need for enhanced adherence counseling or a change to second- line therapy. Low-cost, locally performable alternates to expensive VL assays are needed where resources are limited.We monitored the response to 48-week ART in 100 treatment-naïve Kenyan adults using a low-cost VL measurement, the Cavidi reverse transcriptase (RT) assay and gold-standard assays, Roche RNA PCR and Bayer Versant HIV-1 RNA (bDNA) assays. In Altman-Bland plots, the mean difference in viral loads between the three assays was small (<0.5 log(10) copies/mL). However, the limits of agreement between the methods exceeded the biologically relevant change of 0.5 log copies/ml. Therefore, the RT assay cannot be used interchangeably with the other assays to monitor individual patients. The RT assay was 100% sensitive in detecting viral loads of > or =400 copies/ml compared to gold-standard assays. After 24 weeks of treatment, viral load measured by the RT assay was undetectable in 95% of 65 patients with undetectable RNA PCR VL (<400 copies/ml), 90% of 67 patients with undetectable bDNA VL, and 96% of 57 patients with undetectable VL in both RNA PCR and bDNA assays. The negative predictive value of the RT assay was 100% compared to either assay; the positive predictive value was 86% compared to RNA PCR and 70% compared to bDNA.The RT assay compared well with gold standard assays. Our study highlights the importance of not interchanging viral load assays when monitoring an individual patient. Furthermore, the RT assay may be limited by low positive predictive values when used in populations with low prevalence of virologic failure

    JWST-TST DREAMS: Quartz Clouds in the Atmosphere of WASP-17b

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    Clouds are prevalent in many of the exoplanet atmospheres that have been observed to date. For transiting exoplanets, we know if clouds are present because they mute spectral features and cause wavelength-dependent scattering. While the exact composition of these clouds is largely unknown, this information is vital to understanding the chemistry and energy budget of planetary atmospheres. In this work, we observe one transit of the hot Jupiter WASP-17b with JWST's MIRI LRS and generate a transmission spectrum from 5-12 μ\rm{\mu}m. These wavelengths allow us to probe absorption due to the vibrational modes of various predicted cloud species. Our transmission spectrum shows additional opacity centered at 8.6 μ\rm{\mu}m, and detailed atmospheric modeling and retrievals identify this feature as SiO2_2(s) (quartz) clouds. The SiO2_2(s) clouds model is preferred at 3.5-4.2σ\sigma versus a cloud-free model and at 2.6σ\sigma versus a generic aerosol prescription. We find the SiO2_2(s) clouds are comprised of small 0.01{\sim}0.01 μ\rm{\mu}m particles, which extend to high altitudes in the atmosphere. The atmosphere also shows a depletion of H2_2O, a finding consistent with the formation of high-temperature aerosols from oxygen-rich species. This work is part of a series of studies by our JWST Telescope Scientist Team (JWST-TST), in which we will use Guaranteed Time Observations to perform Deep Reconnaissance of Exoplanet Atmospheres through Multi-instrument Spectroscopy (DREAMS).Comment: 19 pages, 7 figures, accepted for publication in ApJ

    Altering Mucus Rheology to “Solidify” Human Mucus at the Nanoscale

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    The ability of mucus to function as a protective barrier at mucosal surfaces rests on its viscous and elastic properties, which are not well understood at length scales relevant to pathogens and ultrafine environmental particles. Here we report that fresh, undiluted human cervicovaginal mucus (CVM) transitions from an impermeable elastic barrier to non-adhesive objects sized 1 µm and larger to a highly permeable viscoelastic liquid to non-adhesive objects smaller than 500 nm in diameter. Addition of a nonionic detergent, present in vaginal gels, lubricants and condoms, caused CVM to behave as an impermeable elastic barrier to 200 and 500 nm particles, suggesting that the dissociation of hydrophobically-bundled mucin fibers created a finer elastic mucin mesh. Surprisingly, the macroscopic viscoelasticity, which is critical to proper mucus function, was unchanged. These findings provide important insight into the nanoscale structural and barrier properties of mucus, and how the penetration of foreign particles across mucus might be inhibited
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