Variability of cell wall polysaccharides composition and hemicellulose enzymatic profile in an apple progeny

The genetic variability of apple cell walls polysaccharides chemical composition and structure was assessed in a progeny of 141 individuals harvested over 2 years. The variability of the hemicelluloses oligosaccharides released by glucanase was analyzed by MALDI-TOF MS. The genetic contribution was distinguished from harvest year as well as from parental crossing patterns and scab resistance selection. Results showed that harvest year had a major impact on cell wall polysaccharide composition and structure. Within each harvest, genetic effect impact more significantly cell wall polysaccharide chemistry than does reciprocal crossing or early scab selection. Uronic acids, glucose, galactose and xylose contents as well as some glucomannan and xyloglucan structures have a high heritability. This first cell wall chemotyping of an apple progeny opens the way for future searches of genetic markers for the chemical variability of cell wall polysaccharides

Surface state charge dynamics of a high-mobility three dimensional topological insulator

We present a magneto-optical study of the three-dimensional topological insulator, strained HgTe using a technique which capitalizes on advantages of time-domain spectroscopy to amplify the signal from the surface states. This measurement delivers valuable and precise information regarding the surface state dispersion within <1 meV of the Fermi level. The technique is highly suitable for the pursuit of the topological magnetoelectric effect and axion electrodynamics.Comment: Published version, online Sept 23, 201

Evaluation of concrete structures by combining non-destructive testing methods (SENSO project)

The management and maintenance of the built heritage is one of the main interests of the owners of concrete structures. The engineers wish to obtain quantitative information about concrete properties and their variability. Non-destructive testing (NDT) is very popular in this context as it quickly provides relevant information on the integrity and evolution of the material, but several kinds of indicators representative of the concrete condition need to be evaluated. A French Project, named SENSO, aims to develop methods for the non-destructive evaluation of concrete based on a multi-techniques approach. Several families of techniques are concerned (ultrasonic, electromagnetic, electrical, etc.). The main objective is to define the sensitivity of the techniques and the variability of the evaluation for each indicator concerned. To achieve this, a large experimental programme, involving a representative range of concretes and several indicators, has been carried out. A large database, linking the NDT observables and the indicators, allows the different observables to be distinguished in terms of quality (linked to the variability) and in terms of relevance for the characterisation of each indicator. The improvement of the indicator evaluation by means of technique combinatio

Quantifying the Impoverishing Effects of Purchasing Medicines: A Cross-Country Comparison of the Affordability of Medicines in the Developing World

Laurens Niëns and colleagues estimate the impoverishing effects of four medicines in 16 low- and middle-income countries using the impoverishment method as a metric of affordability and show that medicine purchases could impoverish large numbers of people