9 research outputs found
Methodological approach for farm typology construction in terms of soil health – the EU case
Soil health is a significant problem in agriculture which demands a tailor-made approach. The study aims to develop a methodological approach for farm typology construction in terms of soil health. TUdi project, under which was made this study, aims to transform unsustainable management of soils in key cropping systems in Europe and China, developing an integrated platform of alternatives to reverse soil degradation. Thus, the focus is on small, medium, and large EU farms, which produce in the three key cropping systems - grassland, cereal-based rotation, and tree crops. It was applied principal component analysis based on which it was constructed four factors, related to soil health. The results from this analysis was used to feed up the cluster analysis together with other significant variables. The developed farm typology consists of four farm types. From practical point of view was introduced a methodology which allow to determine the type of each farm according the TUdi typology
Методологичен подход за изграждане на типологията на ферми от гледна точка на здравето на почвата случаят на ЕС
[EN] Soil health is a significant problem in agriculture which demands a tailor-made approach. The study aims to develop a methodological approach for farm typology construction in terms of soil health. TUdi project, under which was made this study, aims to transform unsustainable management of soils in key cropping systems in Europe and China, developing an integrated platform of alternatives to reverse soil degradation. Thus, the focus is on small, medium, and large EU farms, which produce in the three key cropping systems – grassland, cereal-based rotation, and tree crops. It was applied principal component analysis based on which it was constructed four factors, related to soil health. The results from this analysis was used to feed up the cluster analysis together with other significant variables. The developed farm typology consists of four farm types. From practical point of view was introduced a methodology which allow to determine the type of each farm according the TUdi typology.[BG] Здравето на почвата е значим проблем в аграрната икономика, които изисква прилагането на индивидуален подход. Целта на настоящата разработка е да се предложи методология за конструиране на типология на ферми, свързана със здравето на почвата. Анализът е реализиран по проект „Tudi“, който цели трансформирането на неустойчивото управление на почвите в ключови системи в Европа и Китай, разработвайки интегрирана платформа за алтернативи за обръщане на деградацията на почвата. В тази връзка фокусът е насочен към малки, средни и големи ферми от страни, членки на ЕС, които произвеждат продукция в трите ключови системи на земеделието – зърнени култури, трайни насаждения и пасища. Използван е анализ на главните компоненти за конструирането на четири фактора, свързани със здравето на почвата. Тези фактори, заедно с други ключови променливи, са анализирани чрез клъстерен анализ за формирането на четири типа ферми. Предложен е подход за определяне на мястото на всяка една ферма в тази типология.The study was developed with the financial help of the European Union’s Horizon 2020 Research and Innovation action under the project “Transforming Unsustainable management of soils in key agricultural systems in EU and China. Developing an integrated platform of alternatives to reverse soil degradation” – TUdi with grant agreement No 101000224.Peer reviewe
Perinatal aspects of haemophilia
Haemophilia is an X-linked recessive genetic disease of haemostasis. Women carriers may present with a bleeding tendency similar to milder forms of the disease. Haemophilic newborns present risk factors and patterns of bleeding that are challenging. Identification of carriers and genetic counselling before conception is considered optimal to help decide on available conception options and during pregnancy to help minimise bleeding risks for both carrier mother and affected baby. Preimplantation genetic diagnosis is attractive to many couples at risk of having a child with haemophilia and relevant technology is becoming more available although it has both practical and ethical limitations. Pregnancy in carriers should be managed by a multidisciplinary team in a comprehensive treatment centre. The optimal mode of delivery for carriers expecting a baby known to have or being at risk of haemophilia is an issue of great debate. The general consensus among authors is avoidance of instrumental delivery, foetal scalp electrodes and blood sampling in pregnancies at risk of carrying an affected foetus, as well as early recourse to Caesarean section as guided by obstetric indications. Intracranial haemorrhage, although infrequent, is one the most devastating types of bleeding in haemophilic newborns and can occur regardless of the mode of delivery or the severity of haemophilia. Early screening is proposed for all infants with severe or moderate haemophilia who have had traumatic delivery and/or have evidence of extracranial haemorrhage. Women with postpartum haemorrhage should have a bleeding work-up
Hemophilia Care in the Pediatric Age
Hemophilia is the most common of the severe bleeding disorders and if not properly managed since early infancy can lead to chronic disease and lifelong disabilities. However, it enjoys the most efficacious and safe treatment among the most prevalent monogenic disorders. Hemophilia should be considered in the neonatal period in the case of unusual bleeding or in the case of positive family history. Later, hemophilia should be suspected mainly in males because of abnormal bruising/bleeding or unusual bleeding following invasive procedures—for example, tonsillectomy or circumcision. Prophylactic treatment that is started early with clotting-factor concentrates has been shown to prevent hemophilic arthropathy and is, therefore, the gold standard of care for hemophilia A and B in most countries with adequate resources. Central venous access catheters and arterovenous fistulas play an important role in the management of hemophilia children requiring repeated and/or urgent administration of coagulation factor concentrates. During childhood and adolescence, personalized treatment strategies that suit the patient and his lifestyle are essential to ensure optimal outcomes. Physical activity is important and can contribute to better coordination, endurance, flexibility and strength. The present article focuses also on questions frequently posed to pediatric hematologists like vaccinations, day-care/school access and dental care
Prolongated Activated Partial Thromboplastin Time (aPTT) in Pediatric Patients before Surgery—Crying Wolf: Lupus (Anticoagulant) Does Not Always Threaten Children
A prolonged preoperatory aPTT in children is often the cause of a delay of scheduled surgeries and the repetition of multiple blood tests, with the consequent wasting of resources and significant discomfort for children and parents. The aim of this review is to analyze the situations in which an isolated prolongation of aPTT is found during preoperative evaluation in children, especially when it is due to the presence of antiphospholipid antibodies, providing the readers with the keys to interpret this situation and the possibility to correctly evaluate the hemorrhagic risk of a patient
Recommendations for the use of long-term central venous catheter (CVC) in children with hemato-oncological disorders: management of CVC-related occlusion and CVC-related thrombosis. On behalf of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP)
Central venous catheters (CVC), used for the management of children with hemato-oncological disorders, are burdened by a significant incidence of mechanical, infective, or thrombotic complications. These complications favor an increasing risk in prolongation of hospitalization, extra costs of care, and sometimes severe life-threatening events. No guidelines for the management of CVC-related occlusion and CVC-related thrombosis are available for children. To this aim, members of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP) reviewed the pediatric and adult literature to propose the first recommendations for the management of CVC-related occlusion and CVC-related thrombosis in children with hemato-oncological disorders
ABCC6 mutations and early onset stroke: Two cases of a typical Pseudoxanthoma Elasticum
Pseudoxanthoma elasticum (PXE) is a rare genetic disorder characterized by fragmented and mineralized elastic fibers in the mid-dermis of the skin, eye, digestive tract and cardiovascular system. Clinical presentation includes typical skin lesions, ocular angioid streaks, and multisystem vasculopathy. The age of onset varies considerably from infancy to old age, but the diagnosis is usually made in young adults due to frequent absence of pathognomonic skin and ocular manifestations in early childhood. We report two children with PXE presenting with isolated multisystem vasculopathy and early-onset stroke. In the first patient, diagnosis was delayed until typical dermatologic alterations appeared; in the second patient, next-generation sequencing (NGS) study led to early diagnosis and specific follow-up, underlying the crucial role in idiopathic pediatric stroke of early genetic testing using NGS-based panels