A Social-Ecological Systems approach to enhance sustainable farming and forestry in the EU

The two concepts of public goods and ecosystem services are often used to describe the same welfare benefits potentially generated by agriculture and forestry, but they originate from different perspectives and each offer only partial analysis of these relationships. A more holistic approach – Social‐Ecological Systems (SES) – has been adapted and applied in new research to understand more fully how the relationships can best be characterised, and beneficial change promoted, through policy reforms and practical action. An important and novel part of the description of a SES, as developed under the PEGASUS project, is the assessment of its ‘valorisation cascade’. Through the mapping and consideration of assets, actors, interactions, drivers and the nature of the valorisation cascade in 34 diverse case studies, the project highlighted the importance of multi‐actor approaches and social processes to foster beneficial change. These include collective action, co‐learning and trust between actors, promoting experimentation and innovation, developing public and/or consumer awareness and identifying new valorisation options, including via commercial supply chains and enhanced community involvement

Etude du rôle des variations de température du manteau dans la structuration et la segmentation des marges continentales passives

TOULOUSE3-BU Sciences (315552104) / SudocTOULOUSE-Observ. Midi Pyréné (315552299) / SudocSudocFranceF

Archéologie du bâti par méthode Géoradar : le cas de la basilique St Seurin

International audienc

Contribution à l'étude de la formolisation des tumeurs malignes (Méthode de O. Laurent)

Thèse : Médecine : Université de Bordeaux : 1913N° d'ordre :

Livedo Reticularis on the Lower Limbs in a Patient with Lupus Erythematosus: A Quiz

Abstract is missing (Quiz

Les politiques régionales de développement rural. Quelles traductions à l’échelle territoriale ?

National audienceCet article analyse les transformations en cours dans la conception et la mise en ½oeuvre des politiques de développement rural à l’échelle de cinq régions européennes. Le champ d’étude correspond au champ du Règlement de Développement Rural (RDR) 2007-2013. Trois principaux résultats sont mis en avant. Le premier concerne la caractérisation des stratégies régionales du point de vue budgétaire et institutionnel. Cette stratégie peut, dans un deuxième temps, être traduite par différents leviers d’intervention. Enfin, une 3ème série de résultats porte sur l'appréciation de la Valeur Ajoutée Territoriale des démarches territoriales et sur celle des déterminants et de la répartition des coûts de transaction inhérents aux mesures de développement rural

Acute Clinical Events Identified as Relapses With Stable Magnetic Resonance Imaging in Multiple Sclerosis

International audienceImportance: Understanding the association between clinically defined relapses and radiological activity in multiple sclerosis (MS) is essential for patient treatment and therapeutic development.Objective: To investigate clinical events identified as relapses but not associated with new T2 lesions or gadolinium-enhanced T1 lesions on brain and spinal cord magnetic resonance imaging (MRI).Design, setting, and participants: This multicenter observational cohort study was conducted between January 2015 and June 2023. Data were extracted on June 8, 2023, from the French MS registry. All clinical events reported as relapses in patients with relapsing-remitting MS were included if brain and spinal cord MRI was performed within 12 and 24 months before the event, respectively, and 50 days thereafter with gadolinium injection.Exposures: Events were classified as relapses with active MRI (RAM) if a new T2 lesion or gadolinium-enhanced T1 lesion appeared on brain or spinal cord MRI or as acute clinical events with stable MRI (ACES) otherwise.Main outcomes and measures: Factors associated with ACES were investigated; patients with ACES and RAM were compared regarding Expanded Disability Status Scale (EDSS) course, relapse rate, confirmed disability accrual (CDA), relapse-associated worsening (RAW), progression independent of relapse activity (PIRA), and transition to secondary progressive (SP) MS, and ACES and RAM rates under each disease-modifying therapy (DMT) were estimated.Results: Among 31 885 clinical events, 637 in 608 patients (493 [77.4%] female; mean [SD] age, 35.8 [10.7] years) were included. ACES accounted for 166 (26.1%) events and were more likely in patients receiving highly effective DMTs, those with longer disease duration (odds ratio [OR], 1.04; 95% CI, 1.01-1.07), or those presenting with fatigue (OR, 2.14; 95% CI, 1.15-3.96). ACES were associated with significant EDSS score increases, lower than those found for RAM. Before the index event, patients with ACES experienced significantly higher rates of relapse (relative rate [RR], 1.21; 95% CI, 1.01-1.46), CDA (hazard ratio [HR], 1.54; 95% CI, 1.13-2.11), and RAW (HR, 1.72; 95% CI, 1.20-2.45). Patients with ACES were at significantly greater risk of SP transition (HR, 2.58; 95% CI, 1.02-6.51). Although RAM rate decreased with DMTs according to their expected efficacy, ACES rate was stable across DMTs.Conclusions and relevance: The findings in this study introduce the concept of ACES in MS, which accounted for one-fourth of clinical events identified as relapses