Detection of risk factors that influence weight loss in patients undergoing radiotherapy

AbstractAimTo identify risk factors that influence weight loss in patients receiving radiotherapy.BackgroundIt is a well-known fact that cancer patients can be affected by malnutrition at the onset of the disease and during treatment due to the toxicity. Pretreatment weight loss alone does not predict those who will need nutritional supplementation. Instead, a variety of nutritional and tumor related factors needs to be taken into account.Material and methodsA retrospective study was conducted on 129 patients with different tumor locations. Weight loss was evaluated during radiotherapy and one month after treatment. The impact of age, ECOG, chemotherapy, pretreatment weight loss, tumor location, previous surgery and TNM were analyzed. We aimed to identify a high-risk group of patients before starting treatment.ResultsThe average net weight loss during radiotherapy and one month after treatment for this group of patients was 0.68kg and 1.6kg, respectively. Median weight loss during radiotherapy was 2.6 kg for head and neck (HN) patients and 0.27 kg for other tumor sites (p=0.028). Median weight loss one month after radiotherapy was 3.7kg for HN patients and 1.1kg for the rest of the patients (p=0.034). The median weight loss one month after treatment was 3.2 kg for patients receiving chemotherapy and 0.5kg for those patients who did not receive chemotherapy (p<0.001). A regression analysis determined that HN tumor location and the use of chemotherapy were independent risk factors.ConclusionsNutritional status must be monitored and managed before, during and after treatment. A variety of nutritional and tumor-related factors must be considered. According to our results, head and neck tumors and the use of chemotherapy are the only two factors considered statistically significant. Because patients continue to lose weight after treatment, we recommend close surveillance after radiotherapy

International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS

La adivinanza : tradición oral y cultura.Construyendo saberes en la escuela

El proyecto La adivinanza, tradición oral y cultura construyendo saberes en la escuela es un análisis de los procesos de construcción de textos a partir de la composición de adivinanzas en el contexto de un taller de escritura con niños y niñas de cuarto y quinto grado de Educación Básica Primaria. En él se desarrolla la implementación de una propuesta pedagógica, la recopilación y el análisis de datos que contribuyan al acercamiento de prácticas literarias y escritas. El propósito del documento es destacar la pertinencia de las adivinanzas como herramientas para la enseñanza de la escritura, a fin de despertar la creatividad, desde la apropiación de saberes lingüísticos y culturales. Para ello se plantean tres aspectos fundamentales: 1. La importancia de las adivinanzas como representación de la cultura; 2. El reconocimiento de elementos en su estructura que le otorgan valor lingüístico y 3. Propuesta en los procesos y estrategias para la enseñanza de su escritura. El análisis se fundamenta desde diversas consideraciones teóricas de la enseñanza del lenguaje como memoria de la colectividad.PregradoLICENCIADO(A) EN LITERATUR

Detection of risk factors that influence weight loss in patients undergoing radiotherapy

AimTo identify risk factors that influence weight loss in patients receiving radiotherapy.BackgroundIt is a well-known fact that cancer patients can be affected by malnutrition at the onset of the disease and during treatment due to the toxicity. Pretreatment weight loss alone does not predict those who will need nutritional supplementation. Instead, a variety of nutritional and tumor related factors needs to be taken into account.Material and methodsA retrospective study was conducted on 129 patients with different tumor locations. Weight loss was evaluated during radiotherapy and one month after treatment. The impact of age, ECOG, chemotherapy, pretreatment weight loss, tumor location, previous surgery and TNM were analyzed. We aimed to identify a high-risk group of patients before starting treatment.ResultsThe average net weight loss during radiotherapy and one month after treatment for this group of patients was 0.68[[ce:hsp sp="0.25"/]]kg and 1.6[[ce:hsp sp="0.25"/]]kg, respectively. Median weight loss during radiotherapy was 2.6 kg for head and neck (HN) patients and 0.27 [[ce:hsp sp="0.25"/]]kg for other tumor sites (p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.028). Median weight loss one month after radiotherapy was 3.7[[ce:hsp sp="0.25"/]]kg for HN patients and 1.1[[ce:hsp sp="0.25"/]]kg for the rest of the patients (p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.034). The median weight loss one month after treatment was 3.2 kg for patients receiving chemotherapy and 0.5[[ce:hsp sp="0.25"/]]kg for those patients who did not receive chemotherapy (p[[ce:hsp sp="0.25"/]