1,573 research outputs found
Stability and Quasinormal Modes of Black holes in Tensor-Vector-Scalar theory: Scalar Field Perturbations
The imminent detection of gravitational waves will trigger precision tests of
gravity through observations of quasinormal ringing of black holes. While
General Relativity predicts just two polarizations of gravitational waves, the
so-called plus and cross polarizations, numerous alternative theories of
gravity predict up to six different polarizations which will potentially be
observed in current and future generations of gravitational wave detectors.
Bekenstein's Tensor-Vector-Scalar (TeVeS) theory and its generalization fall
into one such class of theory that predict the full gamut of six polarizations
of gravitational waves. In this paper we begin the study of quasinormal modes
(QNMs) in TeVeS by studying perturbations of the scalar field in a spherically
symmetric background. We show that, at least in the case where superluminal
propagation of perturbations is not present, black holes are generically stable
to this kind of perturbation. We also make a unique prediction that, as the
limit of the various coupling parameters of the theory tend to zero, the QNM
spectrum tends to times the QNM spectrum induced by scalar
perturbations of a Schwarzschild black hole in General Relativity due to the
intrinsic presence of the background vector field. We further show that the QNM
spectrum does not vary significantly from this value for small values of the
theory's coupling parameters, however can vary by as much as a few percent for
larger, but still physically relevant parameters.Comment: Published in Physical Review
Natural variation in abiotic stress responsive gene expression and local adaptation to climate in Arabidopsis thaliana.
Gene expression varies widely in natural populations, yet the proximate and ultimate causes of this variation are poorly known. Understanding how variation in gene expression affects abiotic stress tolerance, fitness, and adaptation is central to the field of evolutionary genetics. We tested the hypothesis that genes with natural genetic variation in their expression responses to abiotic stress are likely to be involved in local adaptation to climate in Arabidopsis thaliana. Specifically, we compared genes with consistent expression responses to environmental stress (expression stress responsive, "eSR") to genes with genetically variable responses to abiotic stress (expression genotype-by-environment interaction, "eGEI"). We found that on average genes that exhibited eGEI in response to drought or cold had greater polymorphism in promoter regions and stronger associations with climate than those of eSR genes or genomic controls. We also found that transcription factor binding sites known to respond to environmental stressors, especially abscisic acid responsive elements, showed significantly higher polymorphism in drought eGEI genes in comparison to eSR genes. By contrast, eSR genes tended to exhibit relatively greater pairwise haplotype sharing, lower promoter diversity, and fewer nonsynonymous polymorphisms, suggesting purifying selection or selective sweeps. Our results indicate that cis-regulatory evolution and genetic variation in stress responsive gene expression may be important mechanisms of local adaptation to climatic selective gradients
Pleiotropy of FRIGIDA enhances the potential for multivariate adaptation.
An evolutionary response to selection requires genetic variation; however, even if it exists, then the genetic details of the variation can constrain adaptation. In the simplest case, unlinked loci and uncorrelated phenotypes respond directly to multivariate selection and permit unrestricted paths to adaptive peaks. By contrast, 'antagonistic' pleiotropic loci may constrain adaptation by affecting variation of many traits and limiting the direction of trait correlations to vectors that are not favoured by selection. However, certain pleiotropic configurations may improve the conditions for adaptive evolution. Here, we present evidence that the Arabidopsis thaliana gene FRI (FRIGIDA) exhibits 'adaptive' pleiotropy, producing trait correlations along an axis that results in two adaptive strategies. Derived, low expression FRI alleles confer a 'drought escape' strategy owing to fast growth, low water use efficiency and early flowering. By contrast, a dehydration avoidance strategy is conferred by the ancestral phenotype of late flowering, slow growth and efficient water use during photosynthesis. The dehydration avoidant phenotype was recovered when genotypes with null FRI alleles were transformed with functional alleles. Our findings indicate that the well-documented effects of FRI on phenology result from differences in physiology, not only a simple developmental switch
Pressure gradients, shell crossing singularities and acoustic oscillations - application to inhomogeneous cosmological models
Inhomogeneous cosmological models have recently become a very interesting
alternative to standard cosmology. This is because these models are able to fit
cosmological observations without the need for dark energy. However, due to
inhomogeneity and pressure-less matter content, these models can suffer from
shell crossing singularities. These singularities occur when two shell of dust
collide with each other leading to infinite values of the density. In this
Letter we show that if inhomogeneous pressure is included then these
singularities can be prevented from occurring over the period of structure
formation. Thus, a simple incorporation of a gradient of pressure allows for
more comprehensive studies of inhomogeneous cosmological models and their
application to cosmology.Comment: 5 pages, 3 figures. Accepted for publication in MNRA
Gravitational waves from Sco X-1: A comparison of search methods and prospects for detection with advanced detectors
The low-mass X-ray binary Scorpius X-1 (Sco X-1) is potentially the most
luminous source of continuous gravitational-wave radiation for interferometers
such as LIGO and Virgo. For low-mass X-ray binaries this radiation would be
sustained by active accretion of matter from its binary companion. With the
Advanced Detector Era fast approaching, work is underway to develop an array of
robust tools for maximizing the science and detection potential of Sco X-1. We
describe the plans and progress of a project designed to compare the numerous
independent search algorithms currently available. We employ a mock-data
challenge in which the search pipelines are tested for their relative
proficiencies in parameter estimation, computational efficiency, robust- ness,
and most importantly, search sensitivity. The mock-data challenge data contains
an ensemble of 50 Scorpius X-1 (Sco X-1) type signals, simulated within a
frequency band of 50-1500 Hz. Simulated detector noise was generated assuming
the expected best strain sensitivity of Advanced LIGO and Advanced VIRGO ( Hz). A distribution of signal amplitudes was then
chosen so as to allow a useful comparison of search methodologies. A factor of
2 in strain separates the quietest detected signal, at
strain, from the torque-balance limit at a spin frequency of 300 Hz, although
this limit could range from (25 Hz) to (750 Hz) depending on the unknown frequency of Sco X-1. With future
improvements to the search algorithms and using advanced detector data, our
expectations for probing below the theoretical torque-balance strain limit are
optimistic.Comment: 33 pages, 11 figure
Structure of Neutron Stars in Tensor-Vector-Scalar Theory
Bekenstein's Tensor-Vector-Scalar (TeVeS) theory has had considerable success
in explaining various phenomena without the need for dark matter. However, it
is difficult to observationally discern the differences between TeVeS and
predictions made within the Lambda-cold dark matter concordance model. This
implies that alternative tests are required that independently verify which
theory is correct. For this we turn to the strong-field regime of TeVeS. In
particular, we solve the spherically symmetric equations of hydrostatic
equilibrium for a perfect fluid with a realistic equation of state to build
models of neutron stars in TeVeS. We show that causality within the neutron
star is only maintained for certain cosmological values of the scalar field,
which allows us to put constraints on this value independently of cosmological
observations. We also discuss in detail the internal structure of neutron stars
and how each of the free parameters in the theory effects the overall size and
mass of the neutron stars. In particular, the radii of neutron stars in TeVeS
can significantly differ from those in General Relativity for certain values of
the vector field coupling, which allows us to also place extra constraints on
this parameter. Finally, we discuss future observations of neutron stars using
both the electromagnetic and gravitational wave spectrums that will allow for
tests of the appropriate theory of gravity.Comment: Accepted for publication in Phys. Rev.
Epstein - Barr virus latent membrane protein 1 suppresses reporter activity through modulation of promyelocytic leukemia protein-nuclear bodies
The Epstein-Barr virus (EBV) encoded Latent Membrane Protein 1 (LMP1) has been shown to increase the expression of promyelocytic leukemia protein (PML) and the immunofluorescent intensity of promyelocytic leukemia nuclear bodies (PML NBs). PML NBs have been implicated in the modulation of transcription and the association of reporter plasmids with PML NBs has been implicated in repression of reporter activity. Additionally, repression of various reporters in the presence of LMP1 has been noted. This study demonstrates that LMP1 suppresses expression of reporter activity in a dose responsive manner and corresponds with the LMP1 induced increase in PML NB intensity. Disruption of PML NBs with arsenic trioxide or a PML siRNA restores reporter activity. These data offer an explanation for previously conflicting data on LMP1 signaling and calls attention to the possibility of false-positives and false-negatives when using reporter assays as a research tool in cells expressing LMP1
CMB observations in LTB universes: Part I: Matching peak positions in the CMB spectrum
Acoustic peaks in the spectrum of the cosmic microwave background in
spherically symmetric inhomogeneous cosmological models are studied. At the
photon-baryon decoupling epoch, the universe may be assumed to be dominated by
non-relativistic matter, and thus we may treat radiation as a test field in the
universe filled with dust which is described by the Lema\^itre-Tolman-Bondi
(LTB) solution. First, we give an LTB model whose distance-redshift relation
agrees with that of the concordance CDM model in the whole redshift
domain and which is well approximated by the Einstein-de Sitter universe at and
before decoupling. We determine the decoupling epoch in this LTB universe by
Gamow's criterion and then calculate the positions of acoustic peaks. Thus
obtained results are not consistent with the WMAP data. However, we find that
one can fit the peak positions by appropriately modifying the LTB model,
namely, by allowing the deviation of the distance-redshift relation from that
of the concordance CDM model at where no observational data are
available at present. Thus there is still a possibility of explaining the
apparent accelerated expansion of the universe by inhomogeneity without
resorting to dark energy if we abandon the Copernican principle. Even if we do
not take this extreme attitude, it also suggests that local, isotropic
inhomogeneities around us may seriously affect the determination of the density
contents of the universe unless the possible existence of such inhomogeneities
is properly taken into account.Comment: 20 pages, 5 figure
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