Mounting technique for pressure transducers minimizes measurement interferences

Miniaturized transducers are fabricated from commercially available four-arm semiconductor gages; transducers are connected as bridge circuit and mounted on internal face of small diaphragm. Jacket made of conductive plastic may be needed to avoid buildup or static charges

Investigation of the free flow electrophoretic process

The effects of gravity on the free flow electrophoretic process was demonstrated. The free flow electrophoresis chamber used to demonstrate the effects of gravity on the process was of a proprietary design. This chamber was 120 cm long, 16 cm wide, and 0.15 cm thick. Flow in this chamber was in the upward direction and exited through 197 outlets at the top of the chamber. During electrophoresis a stream of sample was injected into the flow near the bottom of the chamber and an electrical field was applied across the width of the chamber. The field caused a lateral force on particles in the sample proportional to the inherent change of the particle and the electric field strength. Particle lateral velocity was then dependent on the force due to viscous drag which was proportional to particle size and particle shape dependent

Attitudes Toward and Perceptions of Pollution by Residents of the Big Stone Lake Area

The objectives of the study were to determine: (1) the attitudes of local residents toward environmental problems; and, (2) whether these attitudes differ when the effects of selected socio-demographic characteristics such as age, education, and income are statiscally controlled in the analysis

Investigation of the free flow electrophoretic process. Volume 1: Executive summary

The effect of gravity on the free flow electrophoretic process was investigated. The demonstrated effects were then compared with predictions made by mathematical models. Results show that the carrier buffer flow was affected by gravity induced thermal convection and that the movement of the separating particle streams was affected by gravity induced buoyant forces. It was determined that if gravity induced buoyant forces were included in the mathematical models, then effective predictions of electrophoresis chamber separation performance were possible

An Exploration of Heterogeneity in Electronic Medical Record Use: Information Technology Use as Emergent and Driven by Values and Expertise

We explore heterogeneity in the use of an organization-wide information technology (IT) by both individuals and groups in a professional organization. We study electronic medical record use by physicians and clinic work groups in two medical practices operating within one multi-specialty health care clinic. Data collection methods include interviews, non-participant observations, and questionnaires. Drawing on theories of professional organizations and complex adaptive systems, we offer as an explanation of heterogeneity in IT use by individuals that IT use is a function of professional values and expertise and of heterogeneity of IT use in groups the insight that IT use at a collective level is an emergent property arising from the interactions of diverse, learning agents. This study contributes to information systems research by enriching current understandings of IT use and by providing new insights about heterogeneous IT use in professional organizations

Are We Putting the Cart Before the Horse? A Microcosm of Intended and Unintended Outcomes of Electronic Medical Record Implementation

Leaders in health care are calling for the implementation of electronic medical records (EMR) systems to help alleviate high costs of care delivery, high error rates, and uneven access to care. However, many of these leaders seem to be overlooking unintended outcomes of EMR implementation. Specifically, they may be overlooking the critical role physician beliefs and relationships play in the use of EMRs and in generating both intended and unintended outcomes. We studied a microcosm of the health care system through a qualitative field study examining EMR use in four clinics operating within a multi-specialty medical organization. We found that beliefs held by physicians about medical practice and the patterns of relationships in clinics influence EMR use behaviors in both expected and unexpected ways. Our contribution is to call attention to unintended outcomes of EMR implementation and to suggest that EMRs can be used as artifacts for learning

Heterogeneity in the growth hormone pituitary gland system of rats and humans: Implications to microgravity based research

The cell separation techniques of velocity sedimentation, flow cytometry and continuous flow electrophoresis were used to obtain enriched populations of growth hormone (GH) cells. The goal was to isolate a GH cell subpopulation which releases GH molecules which are very high in biological activity, it was important to use a method which was effective in processing large numbers of cells over a short time span. The techniques based on sedimentation are limited by cell density overlaps and streaming. While flow cytometry is useful in the analytical mode for objectively establishing cell purity, the numbers of cells which can be processed in the sort mode are so small as to make this approach ineffective in terms of the long term goals. It was shown that continuous flow electrophoresis systems (CFES) can separate GH cells from other cell types on the basis of differences in surface charge. The bioreactive producers appear to be more electrophoretically mobile than the low producers. Current ground based CFES efforts are hampered by cell clumping in low ionic strength buffers and poor cell recoveries from the CFES device

Maternal obesity during pregnancy and lactation influences offspring obesogenic adipogenesis but not developmental adipogenesis in mice

Obesity is an escalating health crisis of pandemic proportions and by all accounts it has yet to reach its peak. Growing evidence suggests that obesity may have its origins in utero. Recent studies have shown that maternal obesity during pregnancy may promote adipogenesis in offspring. However, these studies were largely based on cell culture models. Whether or not maternal obesity impacts on offspring adipogenesis in vivo remains to be fully established. Furthermore, in vivo adipogenic differentiation has been shown to happen at distinct time periods, one during development (developmental adipogenesis—which is complete by 4 weeks of age in mice) and another in adulthood in response to feeding a high-fat (HF) diet (obesogenic adipogenesis). We therefore set out to determine whether maternal obesity impacted on offspring adipocyte hyperplasia in vivo and whether maternal obesity impacted on developmental or obesogenic adipogenesis, or both. Our findings reveal that maternal obesity is associated with enhanced obesogenic adipogenesis in HF-fed offspring. Interestingly, in newly weaned (4-week-old) offspring, maternal obesity is associated with adipocyte hypertrophy, but there were no changes in adipocyte number. Our results suggest that maternal obesity impacts on offspring obesogenic adipogenesis but does not affect developmental adipogenesis

Parallel Quantum Computing Emulation

Quantum computers provide a fundamentally new computing paradigm that promises to revolutionize our ability to solve broad classes of problems. Surprisingly, the basic mathematical structures of gate-based quantum computing, such as unitary operations on a finite-dimensional Hilbert space, are not unique to quantum systems but may be found in certain classical systems as well. Previously, it has been shown that one can represent an arbitrary multi-qubit quantum state in terms of classical analog signals using nested quadrature amplitude modulated signals. Furthermore, using digitally controlled analog electronics one may manipulate these signals to perform quantum gate operations and thereby execute quantum algorithms. The computational capacity of a single signal is, however, limited by the required bandwidth, which scales exponentially with the number of qubits when represented using frequency-based encoding. To overcome this limitation, we introduce a method to extend this approach to multiple parallel signals. Doing so allows a larger quantum state to be emulated with the same gate time required for processing frequency-encoded signals. In the proposed representation, each doubling of the number of signals corresponds to an additional qubit in the spatial domain. Single quit gate operations are similarly extended so as to operate on qubits represented using either frequency-based or spatial encoding schemes. Furthermore, we describe a method to perform gate operations between pairs of qubits represented using frequency or spatial encoding or between frequency-based and spatially encoded qubits. Finally, we describe how this approach may be extended to represent qubits in the time domain as well.Comment: 9 pages, 4 figures, 2018 IEEE International Conference on Rebooting Computing (ICRC

Towards cleaner production: a roadmap for predicting product end-of-life costs at early design concept

The primary objective of the research was to investigate how disposal costs were being incurred in the domain of defence electronic systems by the Original Equipment Manufacturer (OEM) and subsequently to ascertain a novel approach to prediction of their end-of-life (EOL) costs. It is intended that the OEM could utilise this method as part of a full lifecycle cost analysis at the conceptual design stage. The cost model would also serve as a useful guide to aid decision making at the conceptual design stage, so that it may lead to the design of a more sustainable product in terms of recycling, refurbishment or remanufacture with the consideration of financial impact. The novelty of this research is that it identifies the significance of disposal costs from the viewpoint of the OEM and provides a generic basis for evaluation of all the major EOL defence electronic systems. A roadmap has been proposed and developed to facilitate the prediction of disposal costs and this will be used to determine a satisfactory solution of whether the EOL parts of a defence electronic system are viable to be remanufactured, refurbished or recycled from an early stage of a design concept. A selected defence electronic system is used as a case study. Based on the findings, the proposed method offers a manageable and realistic solution so that the OEM can estimate the cost of potential EOL recovery processes at the concept design stag