Validation of a Clinical Scoring System for Outcome Prediction in Dogs with Acute Kidney Injury Managed by Hemodialysis.

BackgroundA scoring system for outcome prediction in dogs with acute kidney injury (AKI) recently has been developed but has not been validated.HypothesisThe scoring system previously developed for outcome prediction will accurately predict outcome in a validation cohort of dogs with AKI managed with hemodialysis.AnimalsOne hundred fifteen client-owned dogs with AKI.MethodsMedical records of dogs with AKI treated by hemodialysis between 2011 and 2015 were reviewed. Dogs were included only if all variables required to calculate the final predictive score were available, and the 30-day outcome was known. A predictive score for 3 models was calculated for each dog. Logistic regression was used to evaluate the association of the final predictive score with each model's outcome. Receiver operating curve (ROC) analyses were performed to determine sensitivity and specificity for each model based on previously established cut-off values.ResultsHigher scores for each model were associated with decreased survival probability (P < .001). Based on previously established cut-off values, 3 models (models A, B, C) were associated with sensitivities/specificities of 73/75%, 71/80%, and 75/86%, respectively, and correctly classified 74-80% of the dogs.Conclusions and clinical relevanceAll models were simple to apply and allowed outcome prediction that closely corresponded with actual outcome in an independent cohort. As expected, accuracies were slightly lower compared with those from the previously reported cohort used initially to develop the models

Beware the Non-uniqueness of Einstein Rings

We explain how an approximation to the rings formed by the host galaxies in lensed QSOs can be inferred from the QSO data alone. A simple ring image can be made from any lens model by a simple piece of computer graphics: just plot a contour map of the arrival-time surface with closely-spaced contours. We go on to explain that rings should be (a) sensitive to time-delay ratios between different pairs of images, but (b) very insensitive to H_0. We illustrate this for the well-known quads 1115+080 and 1608+656.Comment: To appear in AJ (circa Aug 2001

Microwave ISM Emission in the Green Bank Galactic Plane Survey: Evidence for Spinning Dust

We observe significant dust-correlated emission outside of H II regions in the Green Bank Galactic Plane Survey (-4 < b < 4 degrees) at 8.35 and 14.35 GHz. The rising spectral slope rules out synchrotron and free-free emission as majority constituents at 14 GHz, and the amplitude is at least 500 times higher than expected thermal dust emission. When combined with the Rhodes (2.326 GHz), and WMAP (23-94 GHz) data it is possible to fit dust-correlated emission at 2.3-94 GHz with only soft synchrotron, free-free, thermal dust, and an additional dust-correlated component similar to Draine & Lazarian spinning dust. The rising component generally dominates free-free and synchrotron for \nu >~ 14 GHz and is overwhelmed by thermal dust at \nu > 60 GHz. The current data fulfill most of the criteria laid out by Finkbeiner et al. (2002) for detection of spinning dust.Comment: ApJ in press. 26 pages, 11 figures, figures jpeg compressed to save spac

Cost and Benefit Analysis of Tomato Spotted Wilt Virus (TSWV) Management Technology in Georgia.

Recent trend depicts that tomatoes and tomatoes products rank 2nd most important vegetable crop in the United States after potatoes and potatoes products contributing 20 percent of total vegetable production. More-so, tomato is equally ranked 2nd in the United States in terms of production value, generating $1.3 billion after head lettuce that contributed$1.4 billion in the same time period. In 2006, 422,000 acres of tomatoes were planted in the United States. Tomato is equally an important economic crop in the state of Georgia. In 2008, it ranked 14th in the Georgia vegetable acreage as 3,985 acres were planted. It also ranked 6th in terms of farm gate value in the same time period generating $51.2 million. Thrips-vectored tomato spotted wilt virus (TSWV) is a serious disease capable of causing damages to the plant, fruits, quality and reducing yields drastically. Managing TSWV can be complex. For instance, metalized UV-mulch may significantly reduce TSWV, but delay tomato maturity, potentially affecting price and market window. Also, resistant tomato lines may eliminate damages due to TSWV, but could have negative horticultural attributes that standard TSWV-susceptible hybrids do not. TSWV can induce irregular ripening in fruit after packing, affecting post harvest costs. This study is aimed at providing the optimal return per unit of enterprise using cost and benefit estimates of the combination of available inputs used in the various management strategies. Thereafter, the result of the differentially developed techniques and risk-rated cost and benefit budgets will be used to determine which of the risk-rated thrips, TSWV and IPM decision criteria would provide superior pareto-optimal economic and financial benefit to tomato growersTomatoes production, Tomato Spotted Wilt Virus (TSWV), inputs, fixed cost, variable costs, profitability, cost and benefit., Agribusiness, Agricultural and Food Policy, Agricultural Finance, Crop Production/Industries, Environmental Economics and Policy, Farm Management, Financial Economics, Health Economics and Policy, Marketing, Production Economics, Productivity Analysis, Research and Development/Tech Change/Emerging Technologies, Risk and Uncertainty, Teaching/Communication/Extension/Profession,

Aeroelastic model helicopter rotor testing in the Langley TDT

Wind-tunnel testing of a properly scaled aeroelastic model helicopter rotor is considered a necessary phase in the design development of new or existing rotor systems. For this reason, extensive testing of aeroelastically scaled model rotors is done in the Transonic Dynamics Tunnel (TDT) located at the NASA Langley Research Center. A unique capability of this facility, which enables proper dynamic scaling, is the use of Freon as a test medium. A description of the TDT and a discussion of the benefits of using Freon as a test medium are presented. A description of the model test bed used, the Aeroelastic Rotor Experimental System (ARES), is also provided and examples of recent rotor tests are cited to illustrate the advantages and capabilities of aeroelastic model rotor testing in the TDT. The importance of proper dynamic scaling in identifying and solving rotorcraft aeroelastic problems, and the importance of aeroelastic testing of model rotor systems in the design of advanced rotor systems are demonstrated

Parametric Study of an Ablative TPS and Hot Structure Heatshield for a Mars Entry Capsule Vehicle

The National Aeronautics and Space Administration is planning to send humans to Mars. As part of the Evolvable Mars Campaign, different en- try vehicle configurations are being designed and considered for delivering larger payloads than have been previously sent to the surface of Mars. Mass and packing volume are driving factors in the vehicle design, and the thermal protection for planetary entry is an area in which advances in technology can offer potential mass and volume savings. The feasibility and potential benefits of a carbon-carbon hot structure concept for a Mars entry vehicle is explored in this paper. The windward heat shield of a capsule design is assessed for the hot structure concept as well as an ablative thermal protection system (TPS) attached to a honeycomb sandwich structure. Independent thermal and structural analyses are performed to determine the minimum mass design. The analyses are repeated for a range of design parameters, which include the trajectory, vehicle size, and payload. Polynomial response functions are created from the analysis results to study the capsule mass with respect to the design parameters. Results from the polynomial response functions created from the thermal and structural analyses indicate that the mass of the capsule was higher for the hot structure concept as compared to the ablative TPS for the parameter space considered in this study

Correlation of Fermi photons with high-frequency radio giant pulses from the Crab pulsar

To constrain the giant pulse (GP) emission mechanism and test the model of Lyutikov (2007) for GP emission, we have carried out a campaign of simultaneous observations of the Crab pulsar at gamma-ray (Fermi) and radio (Green Bank Telescope) wavelengths. Over 10 hours of simultaneous observations we obtained a sample of 2.1x10^4 giant pulses, observed at a radio frequency of 9 GHz, and 77 Fermi photons, with energies between 100 MeV and 5 GeV. The majority of GPs came from the interpulse (IP) phase window. We found no change in the GP generation rate within 10-120 s windows at lags of up to +-40 min of observed gamma-ray photons. The 95% upper limit for a gamma-ray flux enhancement in pulsed emission phase window around all GPs is 4 times the average pulsed gamma-ray flux from the Crab. For the subset of IP GPs, the enhancement upper limit, within the IP emission window, is 12 times the average pulsed gamma-ray flux. These results suggest that GPs, at least high-frequency IP GPs, are due to changes in coherence of radio emission rather than an overall increase in the magnetospheric particle density.Comment: 9 pages, 6 figures; to appear in The Astrophysical Journal, February 201

Pulsar Science with the Green Bank 43m Telescope

The 43m telescope at the NRAO site in Green Bank, WV has recently been outfitted with a clone of the Green Bank Ultimate Pulsar Processing Instrument (GUPPI \cite{Ransom:2009}) backend, making it very useful for a number of pulsar related studies in frequency ranges 800-1600 MHz and 220-440 MHz. Some of the recent science being done with it include: monitoring of the Crab pulsar, a blind search for transient sources, pulsar searches of targets of opportunity, and an all-sky mapping project. For the Crab monitoring project, regular observations are searched for giant pulses (GPs), which are then correlated with $\gamma$-ray photons from the \emph{Fermi} spacecraft. Data from the all-sky mapping project are first run through a pipeline that does a blind transient search, looking for single pulses over a DM range of 0-500 pc~cm$^{-3}$. These projects are made possible by MIT Lincoln Labs.Comment: 2 pages, 1 figure, to appear in AIP Conference Proceedings of Pulsar Conference 2010 "Radio Pulsars: a key to unlock the secrets of the Universe", Sardinia, October 201

Constraints on changes in fundamental constants from a cosmologically distant OH absorber/emitter

We have detected the four 18cm OH lines from the $z \sim 0.765$ gravitational lens toward PMN J0134-0931. The 1612 and 1720 MHz lines are in conjugate absorption and emission, providing a laboratory to test the evolution of fundamental constants over a large lookback time. We compare the HI and OH main line absorption redshifts of the different components in the $z \sim 0.765$ absorber and the $z \sim 0.685$ lens toward B0218+357 to place stringent constraints on changes in $F \equiv g_p [\alpha^2/\mu]^{1.57}$. We obtain $[\Delta F/F] = (0.44 \pm 0.36^{\rm stat} \pm 1.0^{\rm syst}) \times 10^{-5}$, consistent with no evolution over the redshift range $0 < z < 0.7$. The measurements have a $2 \sigma$ sensitivity of $[\Delta \alpha/\alpha] < 6.7 \times 10^{-6}$ or $[\Delta \mu/\mu] < 1.4 \times 10^{-5}$ to fractional changes in $\alpha$ and $\mu$ over a period of $\sim 6.5$ Gyr, half the age of the Universe. These are among the most sensitive current constraints on changes in $\mu$.Comment: 4 pages, 3 figures. Final version, with minor changes to match the version in print in Phys. Rev. Let