6,495 research outputs found
Exploring the Cosmic Evolution of Habitability with Galaxy Merger Trees
We combine inferred galaxy properties from a semi-analytic galaxy evolution
model incorporating dark matter halo merger trees with new estimates of
supernova and gamma ray burst rates as a function of metallicity from stellar
population synthesis models incorporating binary interactions. We use these to
explore the stellar mass fraction of galaxies irradiated by energetic
astrophysical transients and its evolution over cosmic time, and thus the
fraction which is potentially habitable by life like our own. We find that 18
per cent of the stellar mass in the Universe is likely to have been irradiated
within the last 260 Myr, with GRBs dominating that fraction. We do not see a
strong dependence of irradiated stellar mass fraction on stellar mass or
richness of the galaxy environment. We consider a representative merger tree as
a Local Group analogue, and find that there are galaxies at all masses which
have retained a high habitable fraction (>40 per cent) over the last 6 Gyr, but
also that there are galaxies at all masses where the merger history and
associated star formation have rendered galaxies effectively uninhabitable.
This illustrates the need to consider detailed merger trees when evaluating the
cosmic evolution of habitability.Comment: 11 page, 10 figures. MNRAS accepted 13th Dec 2017. Updated to match
accepted version, with additional discussion of metallicity effect
Higher-dimensional Algebra and Topological Quantum Field Theory
The study of topological quantum field theories increasingly relies upon
concepts from higher-dimensional algebra such as n-categories and n-vector
spaces. We review progress towards a definition of n-category suited for this
purpose, and outline a program in which n-dimensional TQFTs are to be described
as n-category representations. First we describe a "suspension" operation on
n-categories, and hypothesize that the k-fold suspension of a weak n-category
stabilizes for k >= n+2. We give evidence for this hypothesis and describe its
relation to stable homotopy theory. We then propose a description of
n-dimensional unitary extended TQFTs as weak n-functors from the "free stable
weak n-category with duals on one object" to the n-category of "n-Hilbert
spaces". We conclude by describing n-categorical generalizations of deformation
quantization and the quantum double construction.Comment: 36 pages, LaTeX; this version includes all 36 figure
Sulfates on Mars as Markers of Aqueous Processes: An Integrated Multidisciplinary Study of Minerals, Mars Analog sites and Recent Mission Data
Our analyses of sulfate minerals, analog sites, and Martian spectra and spectral images is focused on characterization of the Martian surface and in particular identification of aqueous processes there
Twisted equivariant K-theory, groupoids and proper actions
In this paper we define twisted equivariant K-theory for actions of Lie
groupoids. For a Bredon-compatible Lie groupoid, this defines a periodic
cohomology theory on the category of finite CW-complexes with equivariant
stable projective bundles. A classification of these bundles is shown. We also
obtain a completion theorem and apply these results to proper actions of
groups.Comment: 26 page
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The peripheral blood transcriptome in septic cardiomyopathy: an observational, pilot study.
BACKGROUND:Septic cardiomyopathy (SCM) is common in sepsis and associated with increased morbidity and mortality. Left ventricular global longitudinal strain (LV GLS), measured by speckle tracking echocardiography, allows improved identification of impaired cardiac contractility. The peripheral blood transcriptome may be an important window into SCM pathophysiology. We therefore studied the peripheral blood transcriptome and LV GLS in a prospective cohort of patients with sepsis. RESULTS:In this single-center observational pilot study, we enrolled adult patients (age > 18) with sepsis within 48 h of admission to the ICU. SCM was defined as LV GLS > - 17% based on echocardiograms performed within 72 h of admission. We enrolled 27 patients, 24 of whom had high-quality RNA results; 18 (75%) of 24 had SCM. The group was 50% female and had a median (IQR) age of 59.5 (48.5-67.0) years and admission APACHE II score of 21.0 (16.0-32.3). Forty-six percent had septic shock. After filtering for low-expression and non-coding genes, 15,418 protein coding genes were expressed and 73 had significantly different expression between patients with vs. without SCM. In patients with SCM, 43 genes were upregulated and 30 were downregulated. Pathway analysis identified enrichment in type 1 interferon signaling (adjusted p < 10-5). CONCLUSIONS:In this hypothesis-generating study, SCM was associated with upregulation of genes in the type 1 interferon signaling pathway. Interferons are cytokines that stimulate the innate and adaptive immune response and are implicated in the early proinflammatory and delayed immunosuppression phases of sepsis. While type 1 interferons have not been implicated previously in SCM, interferon therapy (for viral hepatitis and Kaposi sarcoma) has been associated with reversible cardiomyopathy, perhaps suggesting a role for interferon signaling in SCM
Multi-taxa consequences of management for an avian umbrella species
Whether management for so-called umbrella species actually benefits co-occurring biota has rarely been tested. Here, we studied consequences for multiple invertebrate taxa of two ground-disturbance treatments designed to support an avian umbrella species (Eurasian stone-curlew, Burhinus oedicnemus), and whether analysing ecological requirements across the regional species pool predicted beneficiaries. Responses were assessed for the abundance of five bird species of conservation concern, and the abundance, species richness and composition of carabids, staphylinids, other beetles (non-carabid, non-staphylinid), true bugs and ants, sampling 31258 individuals of 402 species in an extensively-replicated experiment across the UK’s largest grass-heath. Both treatments provided suitable habitat for the umbrella species, in contrast to controls. Treatment influenced the abundance of only one bird species; but carabid, other beetle and ant richness increased with one or both treatments, while staphylinid richness and abundance increased and true bug richness and abundance decreased with both treatments. Richness of ‘priority’ (rare, scarce or threatened) invertebrates a priori considered to share ecological requirements with the umbrella species (predicted beneficiaries) increased with both treatments. Resampling and rarefaction showed landscapes diversified by treatment supported a greater cumulative species richness of other beetles, ants and true bugs, and importantly priority invertebrates, than a landscape comprising only untreated controls. Such experiments provide strong evidence to assess co-benefits of umbrella species management, but are costly and time consuming. The systematic examination of the autoecological requirements of co-occurring taxa (the ‘Biodiversity Audit Approach’) successfully predicted likely beneficiaries. Demonstrating wider biodiversity benefits strengthens the case for avian conservation management
Core excitations across the neutron shell gap in ²⁰⁷Tl
The single closed-neutron-shell, one proton-hole nucleus 207Tl was populated in deep-inelastic collisions of a 208Pb beam with a 208Pb target. The yrast and near-yrast level scheme has been established up to high excitation energy, comprising an octupol
Cluster Transformation Coefficients for Structure and Dynamics Calculations in n-Particle Systems: Atoms, Nuclei, and Quarks
The structure and dynamics of an n-particle system are described with coupled
nonlinear Heisenberg's commutator equations where the nonlinear terms are
generated by the two-body interaction that excites the reference vacuum via
particle-particle and particle-hole excitations. Nonperturbative solutions of
the system are obtained with the use of dynamic linearization approximation and
cluster transformation coefficients. The dynamic linearization approximation
converts the commutator chain into an eigenvalue problem. The cluster
coefficients factorize the matrix elements of the (n)-particles or
particle-hole systems in terms of the matrix elements of the (n-1)-systems
coupled to a particle-particle, particle-hole, and hole-hole boson. Group
properties of the particle-particle, particle-hole, and hole-hole permutation
groups simplify the calculation of these coefficients. The particle-particle
vacuum-excitations generate superconductive diagrams in the dynamics of
3-quarks systems. Applications of the model to fermionic and bosonic systems
are discussed.Comment: 13 pages, 5 figures, Wigner Proceedings for Conference Wigner
Centenial Pecs, July 8-12, 200
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