3,697 research outputs found
Some Major Structural Features of the Taconic Allochthon in the Hoosick Falls Area, New York - Vermont
Guidebook for field trips in New York, Massachusetts and Vermont: 61st annual meeting at the State University of New York at Albany, Albany, New York October 10, 11, 12, 1969: Trip 1
Effective antibiotic conservation by emergency antimicrobial stewardship during a drug shortage
We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged.Infect Control Hosp Epidemiol 2017;38:356–359</jats:p
Effectiveness of Cognitive Behavioral Therapy for Depression and Anxiety in Patients With Cardiovascular Disease:A Systematic Review and Meta-Analysis
Rigid C^*-tensor categories of bimodules over interpolated free group factors
Given a countably generated rigid C^*-tensor category C, we construct a
planar algebra P whose category of projections Pro is equivalent to C. From P,
we use methods of Guionnet-Jones-Shlyakhtenko-Walker to construct a rigid
C^*-tensor category Bim whose objects are bifinite bimodules over an
interpolated free group factor, and we show Bim is equivalent to Pro. We use
these constructions to show C is equivalent to a category of bifinite bimodules
over L(F_infty).Comment: 50 pages, many figure
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Loss of testosterone impairs anti-tumor neutrophil function.
In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent changes in immune cell function account for this effect remains unknown. Here, we show that in castrated male mice, neutrophil maturation and function are impaired, leading to elevated metastatic burden in two models of melanoma. Replacement of testosterone effectively normalized the tumor burden in castrated male mice. Further, the aberrant neutrophil phenotype was also observed in prostate cancer patients receiving androgen deprivation therapy, highlighting the evolutionary conservation and clinical relevance of the phenotype. Taken together, these results provide a better understanding of the role of androgen signaling in neutrophil function and the impact of this biology on immune control of malignancies
Information security policy compliance: a higher education case study
Purpose: The purpose of this case study is to examine the factors that impact higher education employees’ violations of information security policy by developing a research model based on grounded theories such as deterrence theory, neutralization theory and justice theory. Design/methodology/approach: The research model was tested using 195 usable responses. After conducting model validation, the hypotheses were tested using multiple linear regression. Findings: The results of the study revealed that procedural justice, distributive justice, severity and celerity of sanction, privacy, responsibility and organizational security culture were significant predictors of violations of information security measures. Only interactional justice was not significant. Research limitations/implications: As with any exploratory case study, this research has limitations such as the self-reported information and the method of measuring the violation of information security measures. The method of measuring information security violations has been a challenge for researchers. Of course, the best method is to capture the actual behavior. Another limitation to this case study which might have affected the results is the significant number of faculty members in the respondent pool. The shared governance culture of faculty members on a US university campus might bias the results more than in a company environment. Caution should be applied when generalizing the results of this case study. Practical implications: The findings validate past research and should encourage managers to ensure employees are involved with developing and implementing information security measures. Additionally, the information security measures should be applied consistently and in a timely manner. Past research has focused more on the certainty and severity of sanctions and not as much on the celerity or swiftness of applying sanctions. The results of this research indicate there is a need to be timely (swift) in applying sanctions. The importance of information security should be grounded in company culture. Employees should have a strong sense of treating company data as they would want their own data to be treated. Social implications: Engaging employees in developing and implementing information security measures will reduce employees’ violations. Additionally, giving employees the assurance that all are given the same treatment when it comes to applying sanctions will reduce the violations. Originality/value: Setting and enforcing in a timely manner a solid sanction system will help in preventing information security violations. Moreover, creating a culture that fosters information security will help in positively affecting the employees’ perceptions toward privacy and responsibility, which in turn, impacts information security violations. This case study applies some existing theories in the context of the US higher education environment. The results of this case study contributed to the extension of existing theories by including new factors, on one hand, and confirming previous findings, on the other hand
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