Imaging Photon Lattice States by Scanning Defect Microscopy

Microwave photons inside lattices of coupled resonators and superconducting qubits can exhibit surprising matter-like behavior. Realizing such open-system quantum simulators presents an experimental challenge and requires new tools and measurement techniques. Here, we introduce Scanning Defect Microscopy as one such tool and illustrate its use in mapping the normal-mode structure of microwave photons inside a 49-site Kagome lattice of coplanar waveguide resonators. Scanning is accomplished by moving a probe equipped with a sapphire tip across the lattice. This locally perturbs resonator frequencies and induces shifts of the lattice resonance frequencies which we determine by measuring the transmission spectrum. From the magnitude of mode shifts we can reconstruct photon field amplitudes at each lattice site and thus create spatial images of the photon-lattice normal modes

Big Bang nucleosynthesis revisited via Trojan Horse Method measurements

Nuclear reaction rates are among the most important input for understanding the primordial nucleosynthesis and therefore for a quantitative description of the early Universe. An up-to-date compilation of direct cross sections of 2H(d,p)3H, 2H(d,n)3He, 7Li(p,alpha)4He and 3He(d,p)4He reactions is given. These are among the most uncertain cross sections used and input for Big Bang nucleosynthesis calculations. Their measurements through the Trojan Horse Method (THM) are also reviewed and compared with direct data. The reaction rates and the corresponding recommended errors in this work were used as input for primordial nucleosynthesis calculations to evaluate their impact on the 2H, 3,4He and 7Li primordial abundances, which are then compared with observations.Comment: 22 pages, 7 figures, accepted for publication in The Astrophysical Journa

A hybrid modified lightweight algorithm for achieving data integrity and confidentiality

Encryption algorithms aim to make data secure enough to be decrypted by an attacker. This paper combines the Speck and the Salsa20 to make it difficult for an attacker to exploit any weaknesses in these two algorithms and create a new lightweight hybrid algorithm called Speck-Salsa20 algorithm for data integrity and confidentiality (SSDIC). SSDIC uses less energy and has an efficient throughput. It works well in both hardware and software and can handle a variety of explicit plaintext and key sizes. SSDIC solves the difficulties of the Speck algorithm. The sequence generated by Speck is not random and fails to meet an acceptable success rate when tested in statistical tests. It is processed by generating a random key using the Salsa20 algorithm. Salsa20 is a high-speed secure algorithm that is faster than advanced encryption standard (AES) and can be used on devices with low resources. It uses a 256-bit key hash function. The recovery of the right half of the original key of the Speck algorithm is also handled by modifying the Speck round function and the key schedule. Simulation results show, according to a National Institute of Standards and Technology (NIST) test, the performance achieved by the SSDIC is increased by nearly 66% more than that achieved from the Speck in terms of data integrity and confidentiality

Quality of life of adolescents with cancer: family risks and resources

PURPOSE: The goal of this study was to evaluate the relative contribution of treatment intensity, family sociodemographic risk, and family resources to health-related quality of life (QOL) of 102 adolescents in treatment for cancer. METHODS: Adolescents and parents completed self-report measures of teen QOL, family functioning, and parent-child bonding. Based on parent report of family sociodemographic variables, an additive risk index was computed. A pediatric oncologist rated treatment intensity. RESULTS: Simultaneous regression analyses demonstrated the significant contribution of roles in family functioning and quality of parent-child relationship to prediction of psychosocial QOL (parent and teen-reported) as well as parent-reported teen physical QOL over and above the contribution of treatment intensity. Family sociodemographic risk did not contribute to QOL in these regression analyses. In additional analyses, specific diagnosis, types of treatment and individual sociodemographic risk variables were not associated with QOL. Parent and teen ratings of family functioning and quality of life were concordant. CONCLUSIONS: Family functioning, including quality of parent-child relationship, are central and potentially modifiable resistance factors in teen QOL while under treatment for cancer. Even more important than relying on diagnosis or treatment, screening for roles and relationships early in treatment may be an important aspect of determining risk for poor QOL outcomes

VIDEO SELF-REFLECTION AND E-MENTORING TO SUPPORT PROFICIENCY IN A HIGH-PERFORMING SCHOOL DISTRICT

Teachers new to a school district are not always equipped with the knowledge, attitudes, and beliefs necessary for expected teacher proficiency and, therefore, need support. The purpose of this concurrent mixed methods convergent design study was twofold: (1) to identify how teacher perceptions about their teaching and self-efficacy changed after content-focused e-mentoring using a teacher development framework and video self-reflection and (2) to investigate whether e-mentoring and video self-reflection supported goal setting, collaboration, and self-reflection. Nine teachers from grades 3-12, with 3-10 years of experience who were new to a high-performing district, met with mentors for an introductory session, four face-to-face sessions, engaged in content-focused asynchronous e-mentoring sessions, and completed video self-reflection. Additional data sources included the Teachers’ Sense of Efficacy Scale and open-ended survey questions. The findings suggest that goal setting, collaboration, and self-reflection occurred and support increases in mentee teacher self-efficacy and professional growth. Furthermore, the findings support the use of a teacher development framework, the Framework for Teaching (Danielson et al., 2009; Danielson, 2011) to guide goal setting in e-mentoring. Most importantly, mentee teachers reflected on the critical incidents from watching a video of their teaching, and were able to identify goals for the future

Erythropoietin and a nonerythropoietic peptide analog promote aortic endothelial cell repair under hypoxic conditions: role of nitric oxide

The cytoprotective effects of erythropoietin (EPO) and an EPO-related nonerythropoietic analog, pyroglutamate helix B surface peptide (pHBSP), were investigated in an in vitro model of bovine aortic endothelial cell injury under normoxic (21% O2) and hypoxic (1% O2) conditions. The potential molecular mechanisms of these effects were also explored. Using a model of endothelial injury (the scratch assay), we found that, under hypoxic conditions, EPO and pHBSP enhanced scratch closure by promoting cell migration and proliferation, but did not show any effect under normoxic conditions. Furthermore, EPO protected bovine aortic endothelial cells from staurosporine-induced apoptosis under hypoxic conditions. The priming effect of hypoxia was associated with stabilization of hypoxia inducible factor-1α, EPO receptor upregulation, and decreased Ser-1177 phosphorylation of endothelial nitric oxide synthase (NOS); the effect of hypoxia on the latter was rescued by EPO. Hypoxia was associated with a reduction in nitric oxide (NO) production as assessed by its oxidation products, nitrite and nitrate, consistent with the oxygen requirement for endogenous production of NO by endothelial NOS. However, while EPO did not affect NO formation in normoxia, it markedly increased NO production, in a manner sensitive to NOS inhibition, under hypoxic conditions. These data are consistent with the notion that the tissue-protective actions of EPO-related cytokines in pathophysiological settings associated with poor oxygenation are mediated by NO. These findings may be particularly relevant to atherogenesis and postangioplasty restenosis

Assessing the presence of Wuchereria bancrofti in vector and human populations from urban communities in Conakry, Guinea

The Global Programme to Eliminate Lymphatic Filariasis was launched in 2000 with the goal of interrupting transmission of lymphatic filariasis (LF) through multiple rounds of mass drug administration (MDA). In Guinea, there is evidence of ongoing LF transmission, but little is known about the most densely populated parts of the country, including the capital Conakry. In order to guide the LF control and elimination efforts, serological and entomological surveys were carried out to determine whether or not LF transmission occurs in Conakry.; The prevalence of circulating filarial antigen (CFA) of Wuchereria bancrofti was assessed by an immuno-chromatography test (ICT) in people recruited from all five districts of Conakry. Mosquitoes were collected over a 1-year period, in 195 households in 15 communities. A proportion of mosquitoes were analysed for W. bancrofti, using dissection, loop-mediated isothermal amplification (LAMP) assay and conventional polymerase chain reaction (PCR).; CFA test revealed no infection in the 611 individuals examined. A total of 14,334 mosquitoes were collected; 14,135 Culex (98.6 %), 161 Anopheles (1.1 %) and a few other species. Out of 1,312 Culex spp. (9.3 %) and 51 An. gambiae (31.7 %) dissected, none was infected with any stage of the W. bancrofti parasite. However, the LAMP assay revealed that 1.8 % of An. gambiae and 0.31 % of Culex spp. were positive, while PCR determined respective prevalences of 0 % and 0.19 %.; This study revealed the presence of W. bancrofti DNA in mosquitoes, despite the apparent absence of infection in the human population. Although MDA interventions are not recommended where the prevalence of ICT is below 1 %, the entomological results are suggestive of the circulation of the parasite in the population of Conakry. Therefore, rigorous surveillance is still warranted so that LF transmission in Conakry would be identified rapidly and adequate responses being implemented